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Confabulation
Wikipedia
Additionally, research suggests that confabulation can be seen in patients with frontal lobe syndrome, which involves an insult to the frontal lobe as a result of disease or traumatic brain injury (TBI). [31] [32] [33] Finally, rupture of the anterior or posterior communicating artery, subarachnoid hemorrhage, and encephalitis are also possible causes of confabulation. [13] [34] Location of brain lesions [ edit ] Confabulation is believed to be a result of damage to the right frontal lobe of the brain. [3] In particular, damage can be localized to the ventromedial frontal lobes and other structures fed by the anterior communicating artery (ACoA), including the basal forebrain, septum, fornix, cingulate gyrus, cingulum, anterior hypothalamus, and head of the caudate nucleus. [35] [36] Developmental differences [ edit ] While some recent literature has suggested that older adults may be more susceptible than their younger counterparts to have false memories, the majority of research on forced confabulation centers around children. [37] Children are particularly susceptible to forced confabulations based on their high suggestibility. [38] [39] When forced to recall confabulated events, children are less likely to remember that they had previously confabulated these situations, and they are more likely than their adult counterparts to come to remember these confabulations as real events that transpired. [40] Research suggests that this inability to distinguish between past confabulatory and real events is centered on developmental differences in source monitoring. ... P.; Freedman, M (1984). "Amnesia after anterior communicating artery aneurysm rupture". Neurology . 34 (6): 752–57. doi : 10.1212/wnl.34.6.752 . ... "Memory disturbances following anterior communicating artery rupture". Annals of Neurology . 31 (5): 473–80. doi : 10.1002/ana.410310503 .
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Personality Disorder
Wikipedia
Alternately moody and irritable, then sullen and withdrawn. Withhold emotions. Will not communicate when there is something problematic to discuss. [33] [ unreliable medical source? ... This group have been termed the Type R, or treatment-resisting personality disorders, as opposed to the Type S or treatment-seeking ones, who are keen on altering their personality disorders and sometimes clamor for treatment. [35] The classification of 68 personality disordered patients on the caseload of an assertive community team using a simple scale showed a 3 to 1 ratio between Type R and Type S personality disorders with Cluster C personality disorders being significantly more likely to be Type S, and paranoid and schizoid (Cluster A) personality disorders significantly more likely to be Type R than others. [39] Presentation [ edit ] Comorbidity [ edit ] There is a considerable personality disorder diagnostic co-occurrence. ... Milieu therapy , a kind of group-based residential approach, has a history of use in treating personality disorders, including therapeutic communities . The practice of mindfulness that includes developing the ability to be nonjudgmentally aware of unpleasant emotions appears to be a promising clinical tool for managing different types of personality disorders. [69] [70] There are different specific theories or schools of therapy within many of these modalities. ... On the one hand, an individual may not consider themselves to have a mental health problem, while on the other, community mental health services may view individuals with personality disorders as too complex or difficult, and may directly or indirectly exclude individuals with such diagnoses or associated behaviors. [71] The disruptiveness that people with personality disorders can create in an organisation makes these, arguably, the most challenging conditions to manage.SLC6A4, DRD2, GABRB3, MTA2, CHD2, SCN1A, MAPK10, KCTD17, SPG21, DNM1, CBS, CUX2, XK, TOR1A, SGCE, MAOA, SFSWAP, ITSN2, TPH2, SNAP25, PRL, WASF2, BRAP, ZNF185, CPSF4, THAS, SOX4, SPOCK3, KCNIP4, AMPD1, NHS, NRAS, LMNA, CHRNA7, COMT, CRP, CYP2D6, DPYD, DRD3, DRD4, TSC22D3, FGF9, NR3C1, HTR1A, HTR1B, HTR2A, IL6, IMPA1, DDX53
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Col1a1/2 Osteogenesis Imperfecta
Gene_reviews
The sensitivity of biochemical testing is approximately 90% in individuals with clinically confirmed OI [Wenstrup et al 1990; PH Byers, personal communication]. Biochemical analysis is essentially no longer used clinically with the advances in molecular diagnostics. ... Methods used may include quantitative PCR, long-range PCR, multiplex ligation-dependent probe amplification (MLPA), and a gene-targeted microarray designed to detect single-exon deletions or duplications. 6. PH Byers, personal communication 7. Sequence analysis of COL1A1 and COL1A2 cDNA to detect pathogenic variants in the coding sequence and sequence analysis of COL1A1 and COL1A2 genomic DNA to detect pathogenic variants that alter either sequence or stability of mRNA identify close to 100% of pathogenic variants in these two genes. 8. van Dijk et al [2010] and data derived from Human Gene Mutation Database [Stenson et al 2017] Clinical Characteristics Clinical Description The severity of COL1A1/2 osteogenesis imperfecta ( COL1A1/2 -OI) ranges from perinatal lethality to individuals with severe skeletal deformities, mobility impairments, and very short stature to nearly asymptomatic individuals with a mild predisposition to fractures, normal stature, and normal life span.COL1A1, COL1A2, SERPINF1, CRTAP, P3H1, SPARC, WNT1, TMEM38B, PLOD2, P4HB, MESD, PPIB, SERPINH1, TENT5A, TAPT1, SMPD3, SMAD4, SUCO, CREB3L1, FKBP10, BMP1, IFITM5, SOST, PPP1R2C, BGLAP, DMD, BEST1, GH1, ACVR2B, SEC24D, PNPLA2, FGFR3, AGA2, PLS3, COX8A, DCN, LRP5, TLL1, PDIA2, GPATCH8, RER, WWTR1, MTCO2P12, PADI1, EFEMP2, PLA1A, MBTPS2, GPR180, NBAS, MED18, LINC01672, TRAP, MIR29B2, MIR29B1, MIR145, SP7, ACTB, EIF2AK3, TNC, ALPL, BAAT, BGN, TSPO, KRIT1, CD38, CD44, CHRM3, COL3A1, COL5A1, CSF2, DLX3, FN1, MSTN, IGF1, TNFSF11, LAMC2, LOX, LRP6, COX2, PPP1CB, PTH, PTGS2, RNASE1, SRSF2, SLC6A2, TNXB, TSC1, TSHR, CXCR4, LOC107984355
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Niemann-Pick Disease Type C
Gene_reviews
Speech & language Comprehensive communication eval by speech & language therapist Assess for need for speech therapy &/or Augmentative and Alternative Communication. ... Assess: Use of community or online resources such as Parent to Parent; Need for social work involvement for parental/caregiver support; Need for advance care planning. ... Speech & language Speech therapy Consider eval for alternative means of communication (e.g., Augmentative and Alternative Communication) for those w/expressive language difficulties. ... Consultation with a developmental pediatrician is recommended to ensure the involvement of appropriate community, state, and educational agencies (US) and to support parents in maximizing quality of life. ... Speech & language Comprehensive communication eval by speech & language therapist Ophthalmology assessment Document progression of saccadic eye movement velocity & presence of gaze palsy, response to miglustat therapy.NPC1, LIPA, NPC2, PDLIM7, APP, SMPD1, PSMB9, ABCA1, RASSF1, CDKN2A, TNF, CHIT1, LINC01193, ERCC2, FCER2, IFNG, LAMP1, LDLR, CD274, MAPT, VEGFA, BACE1, PTCH1, CCL2, SOX2, TP53, ERCC1, H3P10, ATM, CKS1B, SRRM2, APOE, POSTN, APOD, WIF1, CUL9, NBEAL2, SIRT1, TARDBP, SEZ6L, SCO2, ARL2BP, DDX58, APC, TRIM29, DKK3, PDCD4, TMEM97, ANXA6, HDAC6, RAB9A, ATP7B, CD163, TRAF1, UBE2N, UGCG, VHL, VIM, VIP, ZNF154, BSND, ARID1A, ULK1, NR0B2, BECN1, CDK5R1, PER2, ST3GAL5, SPHK1, ARF6, FOXP3, ZMYND10, GDE1, MIR185, NEGR1, NPCA1, H19, STPG4, CELIAC2, ANXA1, MIR10B, MIR130A, MIR203A, RTRAF, MIR31, POU5F1P3, POU5F1P4, UCA1, MIR663A, APOBEC3A_B, UPK3B, CNE-2, NPB, APOBEC3A, ARHGAP42, CKS1BP7, NLK, OTUD4, NLRP2, LPAR5, GBA2, OVOL2, NEUROG2, ROBO3, GORASP1, WNK1, SPNS1, HAVCR2, FATE1, SCGB3A1, CDCA5, SEZ6, OSCP1, TP73, B2M, CP, CD58, GCHFR, GFAP, HCRT, HDAC2, HLA-A, HOXC6, HSPB1, HSP90AA1, IGFBP6, XRCC6, IL1A, IL1B, IL12A, IL17A, JAK2, JUN, JUNB, JUND, GBA, FOSB, THBS1, EGR1, CPT1A, CRP, CTLA4, CTNNB1, DAP, DAPK1, TYMP, S1PR3, EPHA2, FOS, EIF4E, CDKN2B, CDK5, FASN, CDH1, FCN2, FGF2, FOXM1, CD40, SCARB1, LGALS9, SLC6A8, RBM3, RELA, REST, SATB1, BSG, ALB, CCL18, SFRP1, SLPI, CCK, BMP2, BCL2, STAR, STAT3, SYT1, TRBV20OR9-2, TERT, TGFBR1, PLAAT4, PVALB, PTPN12, PTPN6, CAV1, MGMT, MLH1, MMP1, MNAT1, MYC, NBN, CASP8, OSM, OTC, PAK1, ABCB1, PIK3CA, POU5F1, CALR, CALCR, PTK2, CCL5
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Skin Condition
Wikipedia
Of these, keratinocytes are the major component, constituting roughly 95% of the epidermis. [16] This stratified squamous epithelium is maintained by cell division within the stratum basale, in which differentiating cells slowly displace outwards through the stratum spinosum to the stratum corneum, where cells are continually shed from the surface. [16] In normal skin, the rate of production equals the rate of loss; about two weeks are needed for a cell to migrate from the basal cell layer to the top of the granular cell layer, and an additional two weeks to cross the stratum corneum. [23] Dermis [ edit ] Main article: Dermis The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis . [24] The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone. [24] Structural components of the dermis are collagen , elastic fibers , and ground substance also called extra fibrillar matrix. [24] Within these components are the pilosebaceous units, arrector pili muscles, and the eccrine and apocrine glands . [21] The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. [21] [25] The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound healing. [26] [27] Subcutaneous tissue [ edit ] Main article: Subcutaneous tissue The subcutaneous tissue is a layer of fat between the dermis and underlying fascia . [5] This tissue may be further divided into two components, the actual fatty layer, or panniculus adiposus , and a deeper vestigial layer of muscle, the panniculus carnosus . [16] The main cellular component of this tissue is the adipocyte , or fat cell. [5] The structure of this tissue is composed of septal (i.e. linear strands) and lobular compartments, which differ in microscopic appearance. [21] Functionally, the subcutaneous fat insulates the body, absorbs trauma, and serves as a reserve energy source. [5] Diseases of the skin [ edit ] For a comprehensive list, see List of cutaneous conditions . ... Diagnoses [ edit ] The physical examination of the skin and its appendages, as well as the mucous membranes, forms the cornerstone of an accurate diagnosis of cutaneous conditions. [29] Most of these conditions present with cutaneous surface changes termed "lesions," which have more or less distinct characteristics. [30] Often proper examination will lead the physician to obtain appropriate historical information and/or laboratory tests that are able to confirm the diagnosis. [29] Upon examination, the important clinical observations are the (1) morphology, (2) configuration, and (3) distribution of the lesion(s). [29] With regard to morphology, the initial lesion that characterizes a condition is known as the "primary lesion", and identification of such a lesions is the most important aspect of the cutaneous examination. [30] Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions". [1] However, with that being stated, the lack of standardization of basic dermatologic terminology has been one of the principal barriers to successful communication among physicians in describing cutaneous findings. [21] Nevertheless, there are some commonly accepted terms used to describe the macroscopic morphology, configuration, and distribution of skin lesions, which are listed below. [30] Lesions [ edit ] Primary lesions [ edit ] Chigger bites on human skin showing characteristic welts Macule and patch Papule and plaque Nodules Vesicles and bulla Fissures, erosions and ulcers A pustule on the cheek Macule : A macule is a change in surface color, without elevation or depression and, therefore, nonpalpable, well or ill-defined, [10] variously sized, but generally considered less than either 5 [10] or 10 mm in diameter at the widest point. [30] Patch : A patch is a large macule equal to or greater than either 5 or 10 mm across, [30] depending on one's definition of a macule. [1] Patches may have some subtle surface change, such as a fine scale or wrinkling, but although the consistency of the surface is changed, the lesion itself is not palpable. [29] Papule : A papule is a circumscribed, solid elevation of skin with no visible fluid, varying in size from a pinhead to less than either 5 [10] or 10 mm in diameter at the widest point. [30] Plaque : A plaque has been described as a broad papule, or confluence of papules equal to or greater than 10 mm, [30] or alternatively as an elevated, plateau-like lesion that is greater in its diameter than in its depth. [29] Nodule : A nodule is morphologically similar to a papule in that it is also a palpable spherical lesion less than 10 mm in diameter.FYN, COL7A1, KRT10, DUH1, FLCN, ECM1, IKBKG, ATP2A2, KRT1, USB1, ADAR, KRT9, KRT5, PKP1, POMP, EBP, ADA, MBTPS2, SLC29A3, DSP, TRPV3, KRT14, FOXP3, SASH1, SPINK5, UBL5, FERMT1, SLURP1, CHST8, SUV39H2, HSDL1, GJB4, TMC8, FLG2, GJB6, TGM1, ABCB6, GJB2, BRAF, CDSN, CTSC, COL17A1, DSG1, EDA, ERCC2, GJA1, GJB3, HAND2, IGFBP3, ITGA6, ITGB4, KRT16, PTCH1, FZD6, CRLF1, SNAP29, GTF2H5
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Junctional Epidermolysis Bullosa
Gene_reviews
Biallelic pathogenic variants in ITGB4 are a rare cause of JEB [Author, personal communication]. 8. Care must be taken to sequence the genomic region of the longest transcript of LAMA3 (NM_198129 .2) rather than one of the shorter transcript variants. 9. ... Carrier risk of all forms of JEB in the US population has been calculated as 1:270 [Author, personal communication]. Carrier risk of JEB generalized severe has been calculated as 1:781 [Nakano et al 2000, Pfendner et al 2001].
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Conduct Disorder
Wikipedia
A number of interactive risk and protective factors exist that can influence and change outcomes, and in most cases conduct disorder develops due to an interaction and gradual accumulation of risk factors. [25] In addition to the risk factors identified under cause, several other variables place youth at increased risk for developing the disorder, including child physical abuse, [25] prenatal alcohol abuse and maternal smoking during pregnancy . [26] Protective factors have also been identified, and most notably include high IQ , being female, positive social orientations, good coping skills, and supportive family and community relationships. [27] However, a correlation between a particular risk factor and a later developmental outcome (such as conduct disorder) cannot be taken as definitive evidence for a causal link. ... Transactional models propose that youth may resort to violence more often as a result of exposure to community violence, but their predisposition towards violence also contributes to neighborhood climate.
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Multiple Sulfatase Deficiency
Gene_reviews
Attenuated infantile MSD is characterized by a slower clinical course in which affected individuals are noted to have growth deficiency (1.5-3 SD below the mean), feeding difficulties, and developmental delay [Ahrens-Nicklas et al 2018], with cognitive disability and neurodegeneration identified in the second year of life (range 3-36 months). The ability to ambulate and communicate with a limited vocabulary may be preserved into late childhood (age 3-9 years), although by age nine most have significant impairments. ... The oldest known person with the condition survived until the fourth decade of life [Author, personal communication]. Individuals with juvenile MSD can retain the ability to walk into their teenage years. ... Special efforts should be made to maintain mobility and social communication skills until such skills are lost.
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Excoriation Disorder
Wikipedia
One U.S. telephone survey found that 16.6% of respondents "picked their skin to the point of noticeable tissue damage" and that 1.4% would qualify as meeting the requirements of excoriation disorder. Another community survey found a rate of 5.4% had excoriation disorder. ... "Prevalence and heritability of skin picking in an adult community sample: A twin study". American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 159B (5): 605–610. doi : 10.1002/ajmg.b.32067 . ... "Prevalence and heritability of skin picking in an adult community sample: A twin study". American Journal of Medical Genetics Part B: Neuropsychiatric Genetics . 159B (5): 605–610. doi : 10.1002/ajmg.b.32067 .
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Meningococcal Disease
Wikipedia
IRIN Africa news has been providing the number of deaths for each country since 1995, [43] [44] [45] [46] and a mass vaccination campaign following a community outbreak of meningococcal disease in Florida was done by the CDC . [47] History and etymology [ edit ] From the Greek meninx (membrane) + kokkos (berry), meningococcal disease was first described by Gaspard Vieusseux during an outbreak in Geneva in 1805. ... "Mass vaccination campaign following community outbreak of meningococcal disease" .CFHR3, CFH, ACE, CFD, ADAM32, FBXO15, CNTNAP5, ZMIZ1, GRM5, PRDM11, OLA1, ALCAM, NUP62, MYO16, TMPRSS15, IL4I1, CES1, SERPINE1, MBL2, TLR4, TNF, IL10, ST11, IL1A, C7, IL1RN, TLR2, IL1B, CD46, FCGR2C, CFP, ABO, SFTPA2, IL4, FCGR2A, FCGR2B, CPB2, DHPS, DEFA4, C5AR2, BPIFA1, TLR9, ENAH, AP2M1, CD14, SERPING1, C11orf40, CEACAM1, CFB, ADRB1, SFTPA1, DEFB1, CXCL10, EGFR, F3, GAPDH, SLC11A1, SFTPD, CXCL11, RELA, CFHR1, PLG, IGHA1, PC, IL1R1, NMB, MIF, ADD1, ALKBH1
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Alcohol Dependence
Wikipedia
There are two major differences between alcohol dependence and alcoholism as generally accepted by the medical community. Alcohol dependence refers to an entity in which only alcohol is the involved addictive agent. ... Dependence Concepts Physical dependence Psychological dependence Withdrawal Disorders Drugs Alcoholism Amphetamine Barbiturate Benzodiazepine Caffeine Cannabis Cocaine Nicotine Opioid Non-drug stimuli Tanning dependence Treatment and management Detoxification Alcohol detoxification Drug detoxification Behavioral therapies Cognitive behavioral therapy Relapse prevention Contingency management Community reinforcement approach and family training Motivational enhancement therapy Motivational interviewing Motivational therapy Physical exercise Treatment programs Drug rehab Residential treatment center Heroin-assisted treatment Intensive outpatient program Methadone maintenance Smoking cessation Nicotine replacement therapy Tobacco cessation clinics in India Twelve-step program Support groups Addiction recovery groups List of twelve-step groups Harm reduction Category:Harm reduction Drug checking Reagent testing Low-threshold treatment programs Managed alcohol program Moderation Management Needle exchange program Responsible drug use Stimulant maintenance Supervised injection site Tobacco harm reduction See also Addiction medicine Allen Carr Category:Addiction Discrimination against drug addicts Dopamine dysregulation syndrome Cognitive control Inhibitory control Motivational salience Incentive salience Sober companion Category v t e Treatment of drug dependence ( N07B ) Nicotine dependence Bupropion Cytisine Lobeline Mecamylamine Varenicline AA ( Clonidine ) Alcohol dependence AD inhibitor ( Disulfiram Calcium carbimide Hydrogen cyanamide ) Acamprosate Opioid antagonists Naltrexone Nalmefene ) κ-Opioid receptor antagonists Aticaprant Topiramate AA ( Clonidine ) Baclofen Phenibut Opioid dependence AA ( Clonidine Lofexidine ) Ibogaine Opioids Buprenorphine ( +naloxone ) Levacetylmethadol Methadone Dihydrocodeine Dihydroetorphine Hydromorphone (extended-release) Morphine (extended-release) Opioid antagonists ( Naltrexone Nalmefene ) Benzodiazepine dependence AA ( Clonidine ) Benzodiazepines ( Diazepam Lorazepam Chlordiazepoxide Oxazepam ) Barbiturates ( Phenobarbital ) Research Salvia divinorum v t e Alcohol and health Alcohol use Alcohol-related crimes Drunk drivers Alcohol-related traffic crashes in the United States Driving under the influence (DUI) Drunk driving in the United States Public intoxication Rum-running Adulterated moonshine / Denatured alcohol List of methanol poisoning incidents Alcoholism Alcohol and Native Americans Alcoholism in adolescence Alcoholism in family systems Collaborative Study on the Genetics of Alcoholism College student alcoholism Disease theory of alcoholism High-functioning alcoholic (HFA) Seeing pink elephants Chemistry Beer chemistry Congener Alcohol congener analysis Ethanol Blood alcohol content Breathalyzer Fusel alcohol Wine chemistry Effects Short-term effects of alcohol consumption Long-term effects of alcohol On memory Subjective response to alcohol Interactions Aging Brain Cancer breast cancer Cortisol Pregnancy Sleep Tolerance / intolerance Weight Beverage-specific Beer: Potomania Red wine: Red wine headache Social issues Alcohol advertising on college campuses Sex Alcohol myopia Alcohol abuse among college students Binge drinking Epidemiology Blackout (alcohol-related amnesia) Blackout Wednesday Drinking game list pregaming Drinking in public Drunk dialing Drunk walking Drunkorexia Dry drunk French paradox Hair of the dog Nightcap Pantsdrunk Passive drinking Binge drinking devices Beer bong Yard of ale Routes of administration Alcohol enema Alcohol inhalation Sconcing Surrogate alcohol Related issues Balconing Suicide History Dionysian Mysteries Dipsomania Gin Craze List of deaths through alcohol Rum ration Speakeasy General Beer day Drinking culture Apéritif and digestif Hangover remedies Health effects of wine Wine and food matching Long-distance race involving alcohol List of countries by alcohol consumption per capita Alcohol consumption by youth in the United States Nip joint Alcohol control Alcohol law Administrative license suspension (ALS) Alcohol packaging warning messages Drunk driving law by country DWI court Field sobriety testing Hip flask defence Ignition interlock device Legal drinking age Age controversy in US Underage drinking in US List of alcohol laws of US Alcohol prohibition List of countries with alcohol prohibition Neo-prohibitionism Temperance movement Sobriety Alcohol detoxification Alcohol-free zone Dry campus United States open-container laws Designated driver Alcohol rehabilitation Drunk tank Managed alcohol program Non-alcoholic drink List of cocktails List of mixed drinks Spritzer Malt drinks Teetotalism Temperance bar Twelve-step groups Al-Anon/Alateen Alcoholics Anonymous (AA): Adult Children of Alcoholics (ACA) Alcohol limitation 0-0-1-3 Alcohol education Alcohol server training FRAMES Dry January Foundation for Advancing Alcohol Responsibility Campaigns Get Your Sexy Back Liquor license Low-alcohol drinks Fermented tea Low-alcohol beer Low-alcoholic malt drinks Small beer Measurement Alcoholic spirits measure Standard drink Recommended maximum intake of alcoholic beverages Addiction medicine Disulfiram-like drugs : disulfiram , calcium carbimide , cyanamide .GABRA2, ALDH2, HTR2A, ADH1C, ADH1B, CYP2E1, OPRM1, NPY, PDYN, SLC6A4, SNCA, CHRNA5, GABBR1, TACR1, TAS2R38, CCKAR, CHRNA3, NPY2R, GABRG2, SLC29A1, SHBG, TACR3, GGT1, ADH4, FTO, SERINC2, CTNNA2, KIAA0040, PKNOX2, LINC02694, KCNJ6, THSD7B, AKR1A1, BDNF, CHRM2, POMC, DBH, MAOA, ANKK1, HTR1B, DRD2, DRD3, DRD4, CRHR1, COMT, SLC6A3, OPRK1, CRH, ALDH1A1, MAOB, GRIN2B, CNR1, TPH1, ADH7, HTR2C, TH, HTR1A, MTHFR, NFKB1, TRH, GATA4, GAD1, APOE, GRIN2A, OPRL1, GABRB1, IL6, GABRA6, HTR3A, CCK, MPDZ, GABRB3, GABRA1, HTR7, SGIP1, IL1RN, IL10, GRM8, LEP, IL1B, GRIN1, MMP9, OPRD1, NR4A2, GLUL, GH1, NTRK2, GAL, GAD2, GABRG1, DRD1, HNMT, SLC6A2, ADH1A, CLOCK, HTR3B, CHRNB4, ADH5, ARSA, CHRNA4, ZNF699, SLC18A2, GRIK1, SNRNP70, GABRB2, SRD5A1, TAC1, CDH11, CDH13, GABRG3, ACE, GRIK3, SLC1A2, TP53, GRM1, TTC12, PTP4A1, ADRA2A, IL1R1, IL1A, SGCE, AKR1C3, SDHAF3, ABO, HMGB1, TKT, CAT, FYN, NTSR1, PHF3, CNTNAP2, DKK2, OXT, CREB1, CHRNB3, CRHBP, NTS, GHS, SLC6A5, RFX4, PENK, XRCC5, KPNA3, AGO1, LRP8, UBAP2, SEMA5A, CXCL8, SLC17A5, GEMIN4, TESK2, TIPARP, PIK3R1, SAT1, LILRA1, KLF11, GALR3, MGLL, GALR2, ZCCHC14, ANKRD7, ARC, RGS4, NRXN3, SLCO3A1, NCAM1, NQO2, TAS2R16, SIGMAR1, KANK1, SLC6A9, C1D, IPO11, SRD5A2, HERPUD1, PCDH12, NEUROD2, PDE10A, AGO2, TFAP2B, SPG21, CYTL1, CARTPT, NRDC, MOG, MOBP, HOMER1, SLC6A1, NPY5R, CNTN6, NAT1, DSCAML1, EPHX1, GRM3, GABRR1, GRM2, CAMK2A, NKAIN1, THEMIS, DPYSL2, OSBPL5, CYP2A13, CDH12, CDH15, GNB3, CNTN4, GLI2, GHSR, GABRA5, AKR1C4, CNR2, NKAIN2, GAPDH, GAP43, GALR1, CALCA, CAMK4, DUSP8, PTK2B, HLA-DRA, PER3, ADCY7, ADH6, NLGN4X, STON2, HAMP, ALDH3B2, ALK, GSTM1, DTNBP1, AR, GRM7, FABP2, CASC4, ASTN1, GABRR2, EP300, EGF, RFC1, CYP2B6, SLC46A1, EGFR, RASGRF2, ECHS1, PDE4B, REN, CDK20, RACK1, CFTR, ADCY5, TBX19, VWF, PHLDA2, SNORA54, NPS, BAG3, MIR382, BHMT, TF, ST18, CARS1, GPHN, NPSR1, CDH5, CDH8, CDH9, EPHA8, CDH18, CDH10, GGH, FOLR1, MMP2, MBP, NAP1L4, FKBP5, LHB, GFAP, IL17A, FSHB, ANAPC1, TAGLN3, PCDH10, PPP1R1B, HDAC2, NMUR2, SLC22A18, AVPR1B, BRAP, SEMA3A, UTP20, ARL15, AGBL4, STAT3, RARA, PECR, LHPP, MREG, ANKS1B, KLF12, PML, STK40, C1orf220, CCSER1, FIP1L1, NCALD, FSTL5, AVP, NUMA1, NRXN1, PPP1R16B, RHOG, SLC39A8, GSS, STX18-AS1, TRPC4AP, LINC02268, ZBTB16, FAM162A, LINC01818, LINC02661, ESRRG, RN7SL697P, ADAMTSL1, AOX3P, PLGRKT, NSG1, AOX3P-AOX2P, STAT5B, BCOR, MBNL2, SLC6A6, C15orf32, NPM1, GCKR, STAG3, CSRNP3, IGSF22, IGSF9B, PRKAR1A, IRF2BP2, SETD5, TBL1XR1, GRK5, MICB, NCOA6, LYZ, MAP3K4, PLCL2, NABP1, RHBDL2, TMEM260, C16orf72, GRM5, ALLC, DDX53, LINC02210-CRHR1, LOC110806262, PRL, TSPO, SAGE1, GLP1R, GYPE, GYPB, GYPA, TPH2, FLNA, OR2AG1, FAAH, MIR21, ADIPOQ, KL, PER2, PPARA, F9, PNOC, TDO2, CCKBR, APRT, RET, TLR4, SMPD1, SMARCA1, PER1, CFP, PRDM2, NGF, CYP2A6, CCDC6, PTCH1, ESR1, DMTN, F2, EBPL, EPO, IL18R1, WDR20, ELK3, FAT1, PLCD3, EDNRB, ATN1, NLRP3, DNASE1L3, MRGPRF, DBI, OPN4, NPL, FGF2, PARP9, HTT, PCDH19, HCRTR1, CPNE5, HARS1, GUSB, GSTT1, GSR, DCLRE1C, GSK3B, NR3C1, GRIN2C, EFHD2, GPT, GM2A, GDNF, OPA3, EFHC2, PNPLA3, SLC19A3, GCG, CYP3A5, FN1, CYP19A1, COL6A3, CNIH3, AGT, ARNTL, LINC00273, GGTLC5P, GGTLC3, GGT2, GGTLC4P, AIRE, MIR4456, ALDH1B1, THRA1/BTR, MDD2, AGER, AP2B1, ADCYAP1, RN7SL263P, ADCY9, ADCY1, ADA, STIN2-VNTR, LOC111216288, OPN1SW, MDD1, TMEM161B, CDK5, CRP, ZNF366, HHEX, CHRNB1, H19, CHRM5, BTBD8, EYS, CHM, CD40, DST, CD36, CACNA1C, DAGLA, BRCA1, MIR126, MIR141, MIR155, MIR183, MIR19A, NLN, RETN, SLC17A6, PTPN11, RXRB, ARFGEF2, PDLIM5, RNU1-4, BRD2, PPARGC1A, PRSS21, RAB40B, SPACA9, SCN11A, SRSF5, MAPK8, PPAT, KDM6B, PPARG, PPARD, ABAT, PLG, HEY2, RBFOX2, SORT1, SLC1A3, TFIP11, TIMP1, NOL3, ST8SIA4, HGS, XRCC4, UMOD, DLGAP2, PPIG, TYR, TNF, THRA, SMS, THOP1, TGFB1, TFF3, TAT, SYN2, HDAC6, EBI3, SST, DHRS9, PIK3CG, PIK3CD, HLA-B, IL16, MFAP1, MEF2C, MC4R, MARK1, LOX, ABLIM1, KCNN3, KCNK3, IMPA1, IL12B, GDAP1, HTR1E, ACSS2, HSPG2, NPDC1, KCNK13, ARHGEF7, HSD11B2, HRAS, HP, MYC, MYT1, PIK3CB, HPGDS, PIK3CA, AUTS2, PHEX, PGC, PECAM1, PDGFRB, PDE4A, SALL3, PC, OXTR, NF1, NUCB2, NRGN, NPY1R, NOS3, HDGFL3, NGFR, ASCC1, HERC5, NF2, H3P40
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Iron Overload
Wikipedia
Starting during the Mesolithic era , communities of people lived in an environment that was fairly sunny, warm and had the dry climates of the Middle East. ... Over many generations, the human body became well-adapted to a high level of iron content in the diet. [32] In the Neolithic era , significant changes are thought to have occurred in both the environment and diet. Some communities of foragers migrated north, leading to changes in lifestyle and environment, with a decrease in temperatures and a change in the landscape which the foragers then needed to adapt to.HAMP, CP, SLC40A1, BMP6, FTH1, CYBRD1, TF, IREB2, MAPT, ATP2A2, ENTPD1, GGT1, SLC11A2, CHMP2B, HFE, TFR2, TFRC, DMRT1, FXN, HJV, ALAS2, TMPRSS6, EPO, ERFE, UROD, ROS1, IL6, ADIPOQ, EPAS1, NFE2L2, HEPH, FTL, CRP, PGF, ABCB7, HP, HLA-A, GABPA, HMOX1, STAT3, CDAN1, FBXL5, SNCA, CAT, APP, B2M, GDF15, CCL2, ICAM1, HBB, MIR122, HIF1A, SF3B1, DNM1L, PIEZO1, NCOA4, GNPAT, PIK3CG, TP53, TNF, TGFB1, LCN2, GPX4, SLC11A1, PIK3CA, PIK3CB, PIK3CD, SHBG, GSTM1, MAPK8, RN7SL263P, CASP3, COL11A2, APOE, PARP1, RUNX2, RNF19A, SIRT1, SEC23B, AHSA1, CCL27, POLDIP2, WDR45, CUL9, ATRNL1, PRDX5, ISCU, SLC39A14, AQP4, DAPK2, APOC3, DIANPH, GDF11, CASP8AP2, ABCB6, APC, AIMP2, BDNF, BCS1L, DENR, TP63, SOCS1, EIF3A, APLN, PER2, PCSK7, BCL2L1, GRAP2, BCL2, TBPL1, CCL4L2, BAX, ATHS, PTPN22, SLC17A5, VEGFA, AHR, ASRGL1, SESN2, REPS1, GGTLC1, FTMT, SFXN1, SPNS2, SLCO6A1, AGTR1, HAVCR1, AGT, GSTK1, CCL4L1, ACVR1, MIR374A, BOLA2, MIR455, LOC102724197, AKT1, HHIPL2, PINK1, NOD2, PDLIM3, HPGDS, ALPP, NOX4, TRNT1, GLRX5, SLC25A37, PRRX2, UGT1A1, SLC25A38, NAT10, STAB2, SUCNR1, BDH2, MFF, MCOLN1, ALOX5, TRPV1, GPT, UTRN, LEP, SMAD4, SMAD6, SMAD7, SMAD9, DGUOK, MPO, COX2, MUC3A, MUC7, MYD88, NEO1, DES, NGF, NMBR, NPPB, DECR1, PAEP, LRPAP1, NQO1, SERPINA1, IRS1, HBA1, HBA2, GPER1, HTT, GPI, G6PD, MTOR, HLA-B, FOXO3, FDXR, HPX, FANCC, F3, CXCL8, IL10, CXCL10, EPHB2, DDIT3, PIGA, GSTM2, SPP1, CD59, STAT5A, STAT5B, SYP, ADAM17, TBXAS1, TDGF1P3, PRDX2, TERF2, CD38, CBS, CASR, TIMP3, TLR2, TLR4, BMPR1A, BGLAP, SPRR2A, SOD2, CYBB, CD68, CTNNB1, MAPK14, CRMP1, PRB1, PREP, MAPK1, ACO1, REN, CRK, RPE, SERPINB3, SCT, CREB1, CCL4, CCL18, CHIT1, SLPI, USF2
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Atypical Hyperplasia Of The Breast
Mayo_clinic
Ask your doctor about support groups in your community. Another option is online message boards.
- Adjustment Disorders Mayo_clinic
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Cat Body-Type Mutation
Wikipedia
] v t e Domestic cats Felinology Anatomy Genetics Dwarf cat Kitten Odd-eyed cat Squitten Coat genetics Bicolor cat Black cat Calico cat Tabby cat Tortoiseshell cat Health Aging Declawing Diet dental health senior Neutering Spaying Vaccination Behavior Body language Catfight Catnip valerian Communication Meow Purr Kneading Intelligence Play and toys Righting reflex Senses Human–cat interaction Ailurophobia Animal-assisted therapy Bodega cat Cat cafés Cat massage Cat meat Cat-scratch disease Cat show Cats in ancient Egypt Cultural depictions Internet Farm cat Feral cat Cats and Islam Lolcat National Cat Day Puppy cat Ship's cat Zoonosis Registries American Cat Fanciers Association Associazione Nazionale Felina Italiana Canadian Cat Association Cat Aficionado Association Cat Fanciers' Association Fédération Internationale Féline Governing Council of the Cat Fancy Southern Africa Cat Council The International Cat Association World Cat Congress World Cat Federation Breeds ( full list ) ( experimental ) Fully domestic Abyssinian American Curl American Shorthair Balinese Brazilian Shorthair British Shorthair Birman Bombay Burmese Burmilla California Spangled Chartreux Chinese Li Hua Colorpoint Shorthair Cornish Rex Cymric Devon Rex Donskoy Egyptian Mau European Shorthair Exotic Shorthair German Rex Himalayan Japanese Bobtail Javanese Khao Manee Korat Kurilian Bobtail Lykoi Maine Coon Manx Munchkin Norwegian Forest Ocicat Ojos Azules Oriental Shorthair Persian Peterbald Pixie-bob Raas Ragdoll Ragamuffin Russian Blue Scottish Fold Selkirk Rex Siamese Siberian Singapura Snowshoe Somali Sphynx Thai Traditional Persian Tonkinese Toyger Turkish Angora Turkish Van Hybrid Bengal Chausie Highlander Savannah Serengeti Landraces Aegean Cyprus Domestic long-haired Domestic short-haired Kellas Sokoke Van Diseases and disorders Acne Asthma Calicivirus Congenital sensorineural deafness Feline corneal sequestrum Flea Heartworm Hepatic lipidosis Hypertrophic cardiomyopathy Immunodeficiency virus Infectious peritonitis Leukemia virus Lower urinary tract disease Panleukopenia Polydactyly Rabies Ringworm Roundworm Skin disorders Tick Toxoplasmosis Viral rhinotracheitis Book Category
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Craniosynostosis
Mayo_clinic
Ask your health care provider about support groups in your community. If a group isn't for you, maybe your provider can put you in touch with a family who has dealt with craniosynostosis.FGFR2, FGFR1, MSX2, NELL1, TWIST1, EFNB1, TCF12, ERF, SMAD6, ZIC1, ALX4, WDR35, ZNF462, IFT122, RUNX2, BMP2, BBS9, MN1, FREM1, EZH2, AXIN2, FGFR3, GLI3, CDC45, RAB23, POR, CYP26B1, IL11RA, FLNA, PHEX, SMO, TNFSF11, STAT3, RSPRY1, LRP5, ATR, FBN1, PTEN, SNX10, LIG4, ORC6, CENPJ, WDR19, SETD2, RTTN, PSAT1, IL6, FLNB, HNRNPK, GMNN, IFT52, H3-3A, GTF2E2, GRIN2B, LEMD3, MAGEL2, NSUN2, DONSON, PRKAR1A, SPECC1L, CEP152, SLC12A6, NR1I3, MED12, ADAMTS3, RBBP8, SKI, SON, SPG7, KAT6A, MAP3K7, RNF113A, TGFBR1, TGFBR2, TNF, TRPS1, TAS2R38, MASP1, HUWE1, ENPP1, NFIX, TLK2, NPR2, PLK4, ORC4, PCNT, COLEC10, GPC6, TCIRG1, APC2, TRAIP, TRIM13, PPP1CB, PPP3CA, ORC1, SLC35A2, ERCC3, DPH1, CXADR, COLEC11, SLC2A10, CDT1, ATRIP, DMP1, COL10A1, CLCN7, ERCC2, CENPE, CDH11, GNPTAB, CDC6, CD19, NSD1, ARR3, ESCO2, AKT1, ALPL, CXADRP1, MEGF8, SCARF2, GTF2H5, FAT4, MPLKIP, CCBE1, IFT43, CASR, B3GLCT, SLC39A8, POSTN, IL4, MMP9, IL13, IFNG, MUC5AC, SCGB1A1, IL10, IL17A, IL5, RNASE3, CFTR, TLR9, CAMP, CXCL8, PDGFRA, S100A7, S100A8, JAG1, TSLP, IL1B, IL1A, ZMYND10, SPINK5, KRAS, PTGDS, SIRT1, SLC26A4, ABCB1, AHSA1, NDRG1, IFIH1, HLA-DRB1, HMGB1, TNFRSF11B, NT5E, NM, GJA1, MMRN1, CHI3L1, GJB2, OSM, BDNF, MAPK1, KMT2D, AHR, TLR2, DEFB4B, MUC5B, AIMP2, SPP1, EGFR, SHOC2, SNAI1, S100A12, EFNA4, S100A9, NOG, RECQL4, MYDGF, GRAP2, FGF4, FGF8, GPC3, FGF9, CLC, IL2, CRP, CRK, IL22, CSF2, LAMB1, MAPK14, HPGDS, RNF19A, IGF1R, CYP2B6, DEFB4A, POLDIP2, HGF, CYP26A1, IL19, IL6ST, LYZ, KAT6B, IL25, MMP1, PRKRA, MIR150, KCNQ5, PLA2G10, SMC1A, MMP23A, DUOX1, NR1I2, MIR146A, TP63, IL1RL2, ALX1, TRPA1, IL1RL1, TLR7, BPIFA1, CAMKMT, BCL11B, RGS21, SFTPA1, SLC25A24, PGA3, LOC102724971, LOC102723407, UVRAG, VCAM1, TAS2R13, TRPV4, MIR4492, VDR, VIM, TRPV1, OCLN, VWF, GATAD2B, SFTPA2, NOX4, IRAK4, CRLF2, DUOX2, PGA4, SCARA3, MAP1LC3B, CPP, FNDC3B, IL37, CHD7, AGO2, PLA2G2D, B3GAT3, SOX6, KHDRBS1, POLD3, PARS2, SLC52A1, CYSLTR1, CARTPT, GFM1, GJB6, MORF4, CKAP4, PART1, NUDT6, PTGDR2, PPP1R9B, BCL2L12, FGFRL1, TINAGL1, MXD3, CCL26, TFG, IFNL3, TAS2R20, FGFBP1, IGHV3-69-1, MED13L, RAB14, IGHV3OR16-7, CST8, SGSM3, RASD1, ADAMDEC1, RBM45, CST9, LRRK2, SCGB3A2, LRPPRC, NLRP3, SPRY1, AHDC1, GLCCI1, NOD2, IL33, AGER, TNNI3, CYP11B1, FGF2, FES, FCGR3A, ACSL3, F3, F2RL1, ERBB2, EPHA1, EGR2, EGF, DUSP4, DSG3, RCAN1, DPP4, DNASE1, DNAH5, DMBT1, DLX5, DDX5, FGF3, FGF14, FGFR4, GRK5, HSD11B1, HOXD13, HLA-DQB1, HLA-DQA1, MNX1, H2AX, GZMB, CXCL1, GPC1, GAD2, GNB3, GNAS, GLP1R, GLI1, GJB1, GH1, GDF2, GATA3, CYP24A1, CTLA4, IGF1, CCN2, CCND1, BAX, AZGP1, ATP4A, ATP12A, ARSA, ARG2, ARG1, AQP5, AOAH, ANXA7, ANXA6, ANK1, ALX3, ALOX15, ALOX5AP, ALOX5, AGTR1, AGT, BCL2, TNFRSF17, BGLAP, CD8A, CSTA, CST3, CST1, CPB2, COL17A1, CFL1, CD52, CD34, KRIT1, BMP6, SERPINH1, CAV1, CASP3, CALM3, CALM2, CALM1, CAD, BMPR1A, HSPA4, IGH, TLR3, PIK3CG, SCN4A, RPE65, ROS1, REN, RAF1, PTPRO, PTPN11, PTH2R, PTGS2, PTGER4, KLK6, MAPK8, PRG2, POMC, PRRX1, PLG, PLAT, PLA2G2A, PLA2G1B, CCL5, CCL18, CCL21, SPARC, TGFB2, TGFA, TFF1, TAPBP, TAP2, TAP1, SPRR2A, SPRR1B, SMN2, CCL25, SMN1, SIPA1, SFTPD, SFTPB, SFRP4, SDC1, CXCL5, CXCL6, PIN1, PIK3CD, IGHD, PIK3CB, LMX1B, LMNA, LDLR, LCN2, LBP, L1CAM, KCNMA1, JAK1, ITGA3, IRS1, IRF6, CXCL10, TNFRSF9, IL15, IL11, IL9R, IL9, IL6R, IHH, LRPAP1, LTF, CD180, NOS3, PIK3CA, PGA5, PCDH1, PRDX1, OMP, NTRK1, NPPC, NPY, NOS1, SMAD3, NHS, NGF, NFKBIA, MYB, MUC7, COX2, MRC1, MET, MTCO2P12
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Musical Perfect Pitch
Omim
The subjects were selected from the musical communities of 4 large metropolitan areas.
- Leukoencephalopathy, Hereditary Diffuse, With Spheroids Omim
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Rhinorrhea
Wikipedia
External links [ edit ] Coping with colds and flu (NHS Direct) Classification D ICD - 10 : J34.8 ICD - 9-CM : 478.19 DiseasesDB : 26380 External resources MedlinePlus : 003051 v t e Common cold Viruses Adenovirus Coronavirus Enterovirus Rhinovirus Symptoms Cough Fatigue Fever Headache Loss of appetite Malaise Muscle aches Nasal congestion Rhinorrhea Sneezing Sore throat Weakness Complications Acute bronchitis Bronchiolitis Croup Otitis media Pharyngitis Pneumonia Sinusitis Strep throat Drugs Antiviral drugs Pleconaril (experimental) v t e Diseases of the respiratory system Upper RT (including URTIs , common cold ) Head sinuses Sinusitis nose Rhinitis Vasomotor rhinitis Atrophic rhinitis Hay fever Nasal polyp Rhinorrhea nasal septum Nasal septum deviation Nasal septum perforation Nasal septal hematoma tonsil Tonsillitis Adenoid hypertrophy Peritonsillar abscess Neck pharynx Pharyngitis Strep throat Laryngopharyngeal reflux (LPR) Retropharyngeal abscess larynx Croup Laryngomalacia Laryngeal cyst Laryngitis Laryngopharyngeal reflux (LPR) Laryngospasm vocal cords Laryngopharyngeal reflux (LPR) Vocal fold nodule Vocal fold paresis Vocal cord dysfunction epiglottis Epiglottitis trachea Tracheitis Laryngotracheal stenosis Lower RT / lung disease (including LRTIs ) Bronchial / obstructive acute Acute bronchitis chronic COPD Chronic bronchitis Acute exacerbation of COPD ) Asthma ( Status asthmaticus Aspirin-induced Exercise-induced Bronchiectasis Cystic fibrosis unspecified Bronchitis Bronchiolitis Bronchiolitis obliterans Diffuse panbronchiolitis Interstitial / restrictive ( fibrosis ) External agents/ occupational lung disease Pneumoconiosis Aluminosis Asbestosis Baritosis Bauxite fibrosis Berylliosis Caplan's syndrome Chalicosis Coalworker's pneumoconiosis Siderosis Silicosis Talcosis Byssinosis Hypersensitivity pneumonitis Bagassosis Bird fancier's lung Farmer's lung Lycoperdonosis Other ARDS Combined pulmonary fibrosis and emphysema Pulmonary edema Löffler's syndrome / Eosinophilic pneumonia Respiratory hypersensitivity Allergic bronchopulmonary aspergillosis Hamman-Rich syndrome Idiopathic pulmonary fibrosis Sarcoidosis Vaping-associated pulmonary injury Obstructive / Restrictive Pneumonia / pneumonitis By pathogen Viral Bacterial Pneumococcal Klebsiella Atypical bacterial Mycoplasma Legionnaires' disease Chlamydiae Fungal Pneumocystis Parasitic noninfectious Chemical / Mendelson's syndrome Aspiration / Lipid By vector/route Community-acquired Healthcare-associated Hospital-acquired By distribution Broncho- Lobar IIP UIP DIP BOOP-COP NSIP RB Other Atelectasis circulatory Pulmonary hypertension Pulmonary embolism Lung abscess Pleural cavity / mediastinum Pleural disease Pleuritis/pleurisy Pneumothorax / Hemopneumothorax Pleural effusion Hemothorax Hydrothorax Chylothorax Empyema/pyothorax Malignant Fibrothorax Mediastinal disease Mediastinitis Mediastinal emphysema Other/general Respiratory failure Influenza Common cold SARS Coronavirus disease 2019 Idiopathic pulmonary haemosiderosis Pulmonary alveolar proteinosis
- Multiple Mitochondrial Dysfunctions Syndrome 3 Omim