Extragonadal Teratoma

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Retrieved

2021-01-23

Source

Orphanet

Trials

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Genes

BCL10, CTNNB1, KIT, STK11, POU5F1, NANOG, SETBP1, FGFR3, POU5F1P4, POU5F1P3, ATN1, SOX2, IGHV1-12, TP53, TRRAP, HSP90B1, PLSCR4, KLF4, DMRT1, AFP, RPE65, SRRM2, GRN, SLC22A3, HDAC1, KRAS, CKAP4, MYC, PSMD10, PTBP1, TP63, UVRAG, PNO1, RBMS3, CDX2, MAK16, BMP2, DND1, LIN28A, MSC, NOG, PRPF4, TIPRL, MBD2, ATOH8, PROM1, FSD1L, CREG1, LHX2, ZFP42, REXO1, NANOS3, MVP, UTF1, GFI1B, LBX1-AS1, HMGA2, XIST, MIR367, MIR373, CHAC2, MIR375, SYCE1L, NKX2-1, PLAA, KLF2, KLHL1, KAT5, CHD7, FBXW7, LSM2, IMP3, MKS1, ESRP1, DDX4, DCDC2, GMNN, DNMT3L, GAS5, TGFB1, PRDM14, FSD1, METTL8, CBX5, SIRT1, MESD, TDGF1P6, CBX3, ASXL3, ITFG1, GADD45G, HPSE, NES, TIMP1, AAVS1, TFAP2C, ERCC1, ABCC2, CSE1L, CSF2RA, DAZL, DHCR24, EGR1, ELF4, ESR1, TCF12, GPC4, FGF2, FHIT, FOXO3, FMOD, NR5A1, FUT1, CISH, CDKN2B, CDKN2A, CDH1, NR0B1, ALPP, ALPG, BIRC5, AQP4, AR, ATM, BAX, BCL2, BRCA1, BRAF, CALD1, CD1A, CD34, CDK1, GABPA, GATA2, GATA6, MRC1, NHS, NOTCH1, PGM1, PIN1, PMAIP1, PTEN, RB1, SLC3A2, SLC5A5, ACAT1, SNAI1, SNRPN, SRY, SSTR2, ZEB1, NFE2L2, MMP9, GDNF, KITLG, GFRA1, GSTP1, HIF1A, MNX1, HMGA1, IL3, JAG2, KRT10, KRT18, LNPEP, EPCAM, MAT1A, MCL1, ME1, MEFV, PSC

Drugs

Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpesvirus-6, Epstein Barr virus and adenovirus, haematopoietic stem cells and blood progenitors umbilical cord-derived expanded with (1R, 4R)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine dihydrobromide dihydrate

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Extragonadal teratoma is an extremely rare, benign or malignant germ cell tumor characterized, clinically, by a teratoma presenting in an extragonadal location (e.g. retroperitoneum, mediastinum, craniofacial or sacrococcygeal region, intraosseous, solid organs) and, histologically, by displaying well-differentiated structures, as well as immature elements. Presenting symptoms are variable depending on size and location of tumor.