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2018 Amesbury Poisonings
Wikipedia
Retrieved 5 September 2018 . ^ Marlow, Jeremy (27 September 2018). ... BBC News . 5 July 2018 . Retrieved 5 July 2018 . ^ Bannock, Caroline; Dodd, Vikram; Morris, Steven (6 July 2018). ... Metropolitan Police . 13 July 2018 . Retrieved 19 July 2018 . ^ Dodd, Vikram; Morris, Steven (13 July 2018). ... South China Morning Post . 4 September 2018. ^ Tobin, Olivia (5 September 2018). ... Archived from the original on 19 July 2018 . Retrieved 19 July 2018 . ^ Tryhorn, Faye (19 July 2018).
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Abortion In Queensland
Wikipedia
Queensland Government. 23 October 2018 . Retrieved 24 October 2018 . ^ Caldwell, Felicity (17 October 2018). ... Fairfax Media . Retrieved 22 October 2018 . ^ Smee, Ben (17 October 2018). ... The Guardian . Retrieved 25 October 2018 . ^ Horn, Allyson (16 October 2018). ... Queensland Law Reform Commission. June 2018 . Retrieved 25 October 2018 . ^ Layt, Stuart (22 August 2018). ... News.com.au . News Corp Australia. 16 October 2018 . Retrieved 25 October 2018 . ^ Smee, Ben (9 October 2018).
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Hodophobia
Wikipedia
Retrieved 7 June 2018 . "HealthCentral: Hodophobia" . Archived from the original on 12 June 2018 . ... Archived from the original on 12 June 2018 . Retrieved 21 June 2018 . ^ "WebMD_The Fear Factor: Phobias" . ... Archived from the original (PDF) on 2018-06-25 . Retrieved 2018-06-25 . ^ a b c "HealthCentral: Hodophobia" . Archived from the original on 12 June 2018 . Retrieved 7 June 2018 . ^ Bozman, Edward. ... Archived from the original on 21 June 2018 . Retrieved 21 June 2018 . ^ * "CommonPhobias: Hodophobia" .
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Notch2 N-Terminal-Like R
OMIM
Description NOTCH2NLR appears to be a nonfunctional pseudogene derived from a partial duplication of the NOTCH2 gene (600275) (Fiddes et al., 2018). Cloning and Expression Independently, Fiddes et al. (2018) and Suzuki et al. (2018) identified 4 NOTCH2 paralogs in the human genome resulting from segmental duplications of the ancestral NOTCH2 gene that they called NOTCH2NLA (618023), NOTCH2NLB (618024), NOTCH2NLC (618025), and NOTCH2NLR. NOTCH2NLA, NOTCH2NLB, and NOTCH2NLC encode functional NOTCH2-like proteins. Fiddes et al. (2018) determined that NOTCH2NLR is likely a transcribed pseudogene. ... Using RNA sequencing analysis, Suzuki et al. (2018) found that NOTCH2NLA and NOTCH2NLB were expressed throughout corticogenesis in human fetal cortices, with NOTCH2NLB showing higher expression than NOTCH2NLA. ... Gene Structure Independently, Fiddes et al. (2018) and Suzuki et al. (2018) determined that the NOTCH2NL genes, including NOTCH2NLR, contain 5 exons. ... Mapping Independently, Fiddes et al. (2018) and Suzuki et al. (2018) mapped the NOTCH2NLR pseudogene to chromosome 1p11.2, near the NOTCH2 gene.
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Female Genital Mutilation In India
Wikipedia
The Guardian . Retrieved 9 November 2018 . ^ a b c Neeraj, Vartika (23 July 2018). ... "It was a memory I had blocked out, says activist Masooma Ranalvi" . The Hindu . Retrieved 9 November 2018 . ^ Ravishanker, Reshma (8 February 2018). ... Retrieved 9 November 2018 . ^ STP Team (18 February 2017). ... Retrieved 9 November 2018 . ^ Julios, Christina (2018). Female Genital Mutilation and Social Media . ... Hindustan Times . Retrieved 9 November 2018 . ^ "SC refers to five-judge bench plea against female genital mutilation" . 24 September 2018 .
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Havana Syndrome
Wikipedia
Reuters . January 9, 2018. Archived from the original on April 7, 2018 . ... Archived from the original on April 22, 2018 . Retrieved April 22, 2018 . ^ a b c Alexander L. ... Newsweek . Retrieved February 26, 2018 . ^ Bartholomew, Robert E. (January 16, 2018). ... Archived from the original on April 7, 2018 . Retrieved April 7, 2018 . ^ Bartholomew, Robert E. ... Reuters . June 7, 2018. ^ Achenbach, Joel (June 8, 2018).
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Acute Flaccid Myelitis
Wikipedia
Centers for Disease Control and Prevention (CDC) . 17 December 2018. Archived from the original on 21 December 2018 . ... Archived from the original on 22 December 2018 . Retrieved 22 December 2018 . ^ Bitnun, A; Yeh, EA (29 June 2018). ... Centers for Disease Control and Prevention (CDC) . 22 October 2018. Archived from the original on 22 October 2018 . ... Archived from the original on 1 November 2018 . Retrieved 31 October 2018 . ^ Suresh, Sneha; Forgie, Sarah; Robinson, Joan (2018). ... Archived from the original on 2018-11-27 . Retrieved 2018-11-27 . Medicine portal
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Intellectual Developmental Disorder, Autosomal Recessive 70
OMIM
Mild facial dysmorphism, febrile seizures, and behavioral abnormalities have been reported in some patients (Maddirevula et al., 2018; Perez et al., 2018). Clinical Features Maddirevula et al. (2018) described 3 affected children from a consanguineous Malaysian family with cognitive impairment, no dysmorphic features, and normal brain MRIs. One sib was reported to have had febrile seizures. Perez et al. (2018) described a consanguineous Bedouin kindred with 5 children who presented with apparently autosomal recessive severe global developmental delay with no regression, impaired intellectual development with speech delay, aberrant behavior, and mild generalized hypotonia. ... Inheritance The transmission pattern of MRT70 in the families reported by Maddirevula et al. (2018) and Perez et al. (2018) was consistent with autosomal recessive inheritance. Molecular Genetics Maddirevula et al. (2018) reported 3 sibs with MRT70 with a homozygous nonsense mutation in the RSRC1 gene (R90X; 613352.0001). Perez et al. (2018) reported 5 sibs with MRT70 with a homozygous nonsense mutation in the RSRC1 gene (R69X; 613352.0002).
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Abortion In Venezuela
Wikipedia
Guttmacher Institute . Retrieved 13 November 2018 . ^ https://www.un.org/esa/population/publications/abortion/doc/venezuela.doc ^ Kelly, Annie (2018-08-09). ... Brookings . Retrieved 19 October 2018 . ^ Marillier, Lou; Squires, Daisy. ... Reuters . Retrieved 20 October 2018 . ^ a b Zuniga, Mariana (28 November 2017). ... Mayo Clinic . Retrieved 3 October 2018 . ^ Capozza, Korey (December 1998). ... The Telegraph . Retrieved 3 October 2018 . ^ Capozza, Korey (December 1998).
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Rapid Onset Gender Dysphoria Controversy
Wikipedia
Quillette . Archived from the original on 2018-09-23. ^ Littman, Lisa (August 16, 2018). ... Brown University. Archived from the original on 2018-08-19. ^ a b Melchior, Jillian Kay (September 9, 2018). ... ISSN 0099-9660 . Archived from the original on 2018-09-25. ^ "Brown University Statement — Monday, Aug. 27, 2018" . ... ISSN 0307-1235 . Archived from the original on 2018-08-28. ^ Paxson, Christina (September 9, 2018). ... Pediatric and Adolescent Gender Dysphoria Working Group . 2018. Archived from the original on 2018-08-03.
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Deafness, Autosomal Recessive 111
OMIM
Description DFNB111 is characterized by early-onset, moderate to severe sensorineural hearing loss with no vestibular involvement (Wesdorp et al., 2018; Bademci et al., 2018). Clinical Features Wesdorp et al. (2018) reported 8 patients from 3 consanguineous families, 1 Dutch (W05-682) and 2 Turkish (W16-0195, W16-0451), with autosomal recessive nonsyndromic hearing loss. ... There was no vestibular involvement. Bademci et al. (2018) reported 8 patients from 3 unrelated consanguineous families, 2 Turkish and 1 Iranian, with autosomal recessive nonsyndromic sensorineural hearing loss. ... Molecular Genetics By homozygosity mapping and whole-exome sequencing in a consanguineous Dutch family (W05-682) segregating autosomal recessive nonsyndromic hearing loss, Wesdorp et al. (2018) identified homozygosity for a 1-bp deletion (c.72del; 604873.0001) in the MPZL2 gene. ... In affected members of 3 consanguineous families from Turkey and Iran with DFNB111, Bademci et al. (2018) identified homozygosity for the previously identified c.72delA founder mutation in the MPZL2 gene. The mutation segregated with the phenotype in all families. Animal Model Wesdorp et al. (2018) showed that Mpzl2 mutant mice displayed early-onset progressive sensorineural hearing loss that was more pronounced at high frequencies.
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Nipah Virus Infection
Wikipedia
Archived from the original on 23 May 2018 . Retrieved 23 May 2018 . ^ "Prevention Nipah Virus (NiV)" . ... Hindustan Times . 27 May 2018 . Retrieved 28 May 2018 . ^ "After the outbreak" . ... Archived from the original on 22 May 2018 . Retrieved 21 May 2018 . ^ Balan, Sarita (21 May 2018). "6 Nipah virus deaths in Kerala: Bat-infested house well of first victims sealed" . ... The Indian Express . 20 May 2018 . Retrieved 20 May 2018 . ^ "Deadly Nipah virus claims victims in India" . BBC News . 21 May 2018 . Retrieved 11 December 2018 – via www.bbc.com. ^ a b "Kerala Govt Confirms Nipah Virus, 86 Under Observation" .
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Amyotrophic Lateral Sclerosis, Susceptibility To, 25
OMIM
Clinical Features Nicolas et al. (2018) reported 19 patients from 9 unrelated families with ALS associated with heterozygous loss-of-function (LOF) variants in the KIF5A gene. ... Two patients with sporadic disease were also reported: they had onset at ages 50 and 52 years, respectively. Brenner et al. (2018) reported 3 unrelated probands with ALS25. ... Nicolas et al. (2018) speculated that KIF5A variants cause disease by disrupting axonal transport. ... In 3 unrelated probands with familial ALS25, Brenner et al. (2018) identified 3 different mutations in the KIF5A gene (see, e.g., 602821.0017). ... The variants identified were similar to a c.3020+1G-A variant reported in the ALS Variant Server database. Brenner et al. (2018) postulated haploinsufficiency as the pathogenic mechanism.
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Cerebellar Degeneration
Wikipedia
Retrieved 2018-10-09 . ^ "Stroke - Symptoms and causes" . ... Retrieved 2018-10-19 . ^ "Nutritional Deficiencies" . www.clinicaladvisor.com . Retrieved 2018-10-19 . ^ "Alcohol consumption" . ... Retrieved 2018-10-09 . ^ "Cerebellar Disorders - Neurologic Disorders" . Merck Manuals Professional Edition . Retrieved 2018-10-09 . ^ Salman MS (February 2018).CDR1, ATM, CDR2, ATXN3, AKR1C4, PRNP, RUNX1T1, ATXN1, GRM1, MRE11, HSPA5, CACNA1A, PNKP, SYNE1, FLVCR1, CDR2L, SHQ1, TDP1, PNPLA6, NPC2, CTNNBL1, AGTPBP1, PARP1, SAR1A, SLC2A4RG, ZFYVE9, CARD14, ALKBH7, CNTN4, VWA3B, C9orf72, TGM6, MIR148B, MIR202, MIR671, ABCB6, PRDX2, ARHGEF2, HSPB1, APP, C4BPA, CASP3, CSTB, DAB1, ELANE, FRAXA, GABRA3, GRM5, LY6E, AAAS, NPC1, ATXN2, SOX3, SPTBN2, SRY, AP2B1, TOP1, UBA1, UBE2I, AAA1
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Camel Spongiform Encephalopathy
Wikipedia
It was discovered by the Algerian veterinarian Baaissa Babelhadj, Lecturer-researcher Semir Bechir Suheil GAOUAR (university of Tlemcen) and a colleague in Ouargla , in collaboration with Italian researchers. [1] This infection is a form of prion disease ( transmissible spongiform encephalopathy , TSE) that affects camels. [2] [3] References [ edit ] ^ " maghrebemergent.info Deux chercheurs algériens découvrent la maladie du " dromadaire fou " à Ouargla" . Archived from the original on 2018-05-24 . Retrieved 2018-05-27 . ^ " huffpostmaghreb.com Deux chercheurs algériens découvrent la maladie du "chameau fou" à Ouargla" . Archived from the original on 2018-05-24 . Retrieved 2018-05-27 . ^ Babelhadj, B; Di Bari, MA; Pirisinu, L; Chiappini, B; Gaouar, SBS; Riccardi, G; Marcon, S; Agrimi, U; Nonno, R; Vaccari, G (June 2018).
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Rapid ʻōhiʻa Death
Wikipedia
Initially reported by landowners in Puna in 2010, ROD spread quickly across tens of thousands of acres on Hawaii Island : [1] [2] to date, hundreds of thousands of ʻōhiʻa have died from this fungal disease on Hawaii Island alone. [3] In April 2018, the cause of Rapid ʻŌhiʻa Death was identified as two species of Ceratocystis previously unknown to science: Ceratocystis huliohia and Ceratocystis lukuohia . [4] By May 2018, infected ʻōhiʻa trees were found on the island of Kauai , prompting requests that members of the public limit transportation of ʻōhiʻa products within the island. [5] The less aggressive of the two fungus species, C. huliohia , has been confirmed on Hawaii Island , Kauai , Maui , and Oahu . [3] According to experts, the fungus is likely to have been carried between the islands by tourists, on their shoes or hiking boots, but it can also be transmitted by dirty tools, animals or through the wind. [6] In 2019 a documentary titled Saving ʻŌhiʻ’a: Hawaii's Sacred Tree, produced by Club Sullivan and funded by a grant from the Hawaiʻi Invasive Species Council, was released, providing an in-depth look into the cultural and ecological importance of ʻōhiʻa and the impact of the ROD epidemic. The film was nominated for six Emmys and received three awards from the National Academy of Television Arts and Sciences Pacific Southwest Chapter. [7] In 2020, the Rapid ʻŌhiʻa Death Working Group released a "Strategic Response Plan for 2020-2024" laying out management, research, and public engagement priorities to contain the disease and calling for $4 million a year in funding over the next five years to “continue progress toward understanding and addressing the fungal disease that has seriously impacted Hawaii’s native forests.” [8] References [ edit ] ^ Nemo, Leslie (2018-09-20). "Hawaii's "rapid ohia death" disease is killing the forest canopy, and there's no end in sight" . ... University of Hawaiʻi System News . 2018-04-17 . Retrieved 2020-02-06 . ^ Bernardo, Rosemarie (2018-05-11). ... Honolulu Star-Advertiser . Archived from the original on 2018-05-15 . Retrieved 2018-05-14 . ^ "Sacred Hawaiian tree is under threat as tourists are asked to help save it" .
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Mental Retardation, Autosomal Recessive 65
OMIM
Clinical Features Faundes et al. (2018) reported 3 unrelated boys, aged 10, 11, and 18 years, with moderate to severe developmental delay and intellectual disability. ... None had seizures. Martin et al. (2018) reported a 7-year-old boy (Decipher ID 259532) with developmental delay and specific learning disability, attention deficit disorder, sleep disturbance, and generalized joint laxity. ... Inheritance The transmission pattern of MRT65 in the families reported by Faundes et al. (2018) was consistent with autosomal recessive inheritance. Molecular Genetics In 3 unrelated patients with MRT65, Faundes et al. (2018) identified homozygous or compound heterozygous mutations in the KDM5B gene (605393.0001-605393.0004). ... Heterozygous Mutations Martin et al. (2018) reported 9 patients (6 males and 3 females) from the DDD study with de novo heterozygous mutations in the KDM5B gene.
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Nervous System Disease
Wikipedia
See also [ edit ] Central nervous system disease Peripheral neuropathy References [23] [ edit ] ^ "Nervous System Diseases – Neurologic Diseases" . MedlinePlus . Retrieved 2018-02-02 . ^ Breedlove, S. Mark (2018). ... PMID 23097374 . ^ Breedlove, S. Mark (2018). Behavioral Neuroscience . 198 Madison Avenue, New York, NY 10016, USA: Oxford University Press. p. 208. ... S2CID 96435953 . ^ Breedlove, S. Mark (2018). Behavioral Neuroscience . 198 Madison Avenue, New York, NY 10016, USA: Oxford University Press. p. 49. ... S2CID 220112630 . ^ Breedlove, S. Mark (2018). Behavioral Neuroscience . 198 Madison Avenue, New York, NY 10016, USA: Oxford University Press. p. 361. ... PMID 29483778 . ^ Breedlove, S. Mark (2018). Behavioral Neuroscience . 198 Madison Avenue, New York, NY 10016, USA: Oxford University Press. p. 35.TNF, BDNF, GFAP, SCN8A, ACHE, NGF, SOD1, TYMS, SLC2A1, SLC6A3, ABCB1, CASP3, NOTCH1, DPYD, TTPA, CSF3, CHRNA4, PTGS2, PRODH, MTHFR, DHFR, PENK, TTC19, NOS1, ATF3, SELENOP, SLC10A2, CASP9, ASCL1, GUSB, SLC18A2, KCNQ2, SLC19A1, SHMT1, HES5, NOD1, ABCC2, ABCG2, ATXN8OS, FOXG1, NEUROD1, NFATC2, ID3, CYP2C8, CYP2C9, ARFGAP1, MTRR, ADRB2, PNPLA6, FOS, EN1, SERPINE1, CAMKK1, TP53, TARDBP, SNCA, MECP2, HTT, MAPT, CACNA1A, NEFL, ATF7IP, APOE, AQP4, PRNP, NFE2L2, FXN, VEGFA, ATP1A3, CDK5, PRRT2, C9orf72, FMR1, TSPO, EPO, C20orf181, IL6, GAD1, NPC1, GRIN2B, HCRT, GABPA, UBE3A, ARX, L1CAM, TOR1A, OPA1, ACTB, IL10, GLP1R, MTOR, SLC1A2, REST, COMT, MAOA, THBS1, REN, MAOB, CSF2, SETX, APP, DRD2, GCG, LAMC2, MFN2, GLRA1, AR, CSF1R, POLG, PLAT, VCP, MOG, ALB, SIRT1, MIR21, CD46, HMGB1, ENO2, CNTNAP2, ERVW-1, UCHL1, BCHE, CDKL5, HPRT1, ATXN1, FUS, TPI1, WWOX, CHI3L1, SLC12A5, PIK3CA, PIK3CB, TNFRSF1B, MIR146A, DYRK1A, PIK3CD, SNAP25, LGI1, IL1B, PIK3CG, NR2E1, MCF2L, ERVK-20, EHMT1, LCN2, PLA2G6, HDAC6, ZGLP1, IGF1, GCH1, P2RX7, ABCC8, IL17A, XPA, SPTLC1, RELN, CP, CTNNB1, TTR, SCN1A, GAD2, CNR2, CNR1, ABCD1, GNAO1, AHR, ATL1, LRP2, MPZ, FTO, PNKP, AKT1, GRN, NLRP3, PPARG, GRM5, ATM, MGLL, HTR1A, NEFH, HTR7, IFNG, CYFIP2, NDUFS4, IDO1, NCL, EXOSC3, TOLLIP, ITPR1, KCNC3, KIF5A, IL2RB, APTX, LMNB1, GEMIN4, SIGLEC7, CXXC1, MMP9, PYCARD, MSMB, ATP6, DISC1, IGFALS, ITIH4, PSEN1, HSPB8, STXBP3, RIDA, SIGMAR1, TRBV20OR9-2, TCF3, MICU1, SURF1, CFDP1, AAVS1, SPAST, SOX10, SOX2, SLC9A6, SMPD1, SLC12A2, DNM1L, SLC12A6, TOP1, TRPM2, HDAC9, VRK2, ZIC1, SLC6A5, MANF, SLC7A5, EIF2S2, EIF2B2, EIF2B4, DENR, KHSRP, HDAC3, RNMT, CTCF, CCL5, SACS, PITX2, SIRT2, SV2C, PTPA, PLP1, PLG, CYFIP1, NCS1, CCL2, PAFAH1B1, NR4A2, AUTS2, NOVA1, NOTCH3, NHS, MAPK1, MAPK3, PSPN, SMPD3, PSMD2, PSPH, PTEN, PTN, PVALB, PSIP1, REG1A, RIT2, PPARGC1A, SORT1, S100B, ATXN2, SCT, VPS13D, BANF1, FRAXA, GRM2, EPHA4, CASP1, ERCC6, FAAH, CALCA, FANCD2, DDHD1, DDR1, BRCA2, PINK1, AVP, ATP7B, GLUL, ERVK-6, SLC25A19, CHCHD10, APOD, IGLON5, SEMA6A, EIF4G2, EIF2B1, MTDH, CRP, CST3, CUX1, CX3CR1, RBM45, CSH2, CSH1, DAPK1, HSPA4, ACE, DPYSL2, BPIFA2, CREB1, DECR1, DLG3, CLN3, DNMT1, TPP1, CLU, MIR132, CSTB, HDAC2, HDAC1, HLA-DQB1, ADAM10, HCLS1, NRG1, HLA-DRB1, MIR27B, CXCR6, PDIK1L, ARTN, CERS1, HSPB3, CELF2, NRG3, RGPD2, AP3D1, OGA, PROM2, AHSA1, MANEAL, NPC2, MAP7, PLB1, ZSWIM2, PPM1K, ABCA13, AMOT, CXCL13, CBLL2, KAT5, DNAAF4, MIR574, MARCHF10, OXER1, WASF1, NRG4, SEPTIN9, ERVK-18, SYNGAP1, PDCD10, POLG2, ERVK-32, FMR1-IT1, PROM1, WDR45, TPPP, ALKBH1, UPK3B, ACMSD, CDK5R1, IMMT, TCERG1, GPR151, GLIS3, NR1I2, TAAR1, PDE10A, TRIM40, NEU3, MIR147B, CDKN2B-AS1, PIWIL4, TTC36, OR2AG1, CPLX2, FBXL14, PWAR1, GCOM1, SEMA4D, USP14, RLS1, PIWIL1, MALAT1, RAPGEF5, KIAA0319, SV2A, TGM6, KBTBD11, VN1R17P, GRAP2, NACA2, CACNA2D2, SYT10, GPR166P, ABCB5, RAB7B, HDAC4, KRTAP10-1, ADGRG1, EFTUD2, CDNF, MAD2L1BP, CLOCK, LITAF, KL, MIR17HG, PICK1, ADIPOQ, MIR148A, GSTO1, MIR155, MIR212, NTN1, AKT3, LIN9, SRA1, NALCN, MPEG1, ZUP1, HAX1, TOMM40, RBM14, GPRC6A, ANKK1, TUBB4A, USP6, INA, HGS, MFSD8, ATXN7L3B, TUBB3, BDNF-AS, SLC9A9, IRF9, TUBA1B, MRGPRX1, IS1, EXOSC8, H19, PGP, PIGW, MPHOSPH6, PQBP1, BTBD8, ABCB6, LPAR2, SH2B3, PI4K2A, MORC2, NEU4, NGB, SLC40A1, CELF5, GAS5, LGR6, SHANK1, TRPV4, DMRT3, GBA2, NLRP1, TBC1D24, NDUFA13, SEPSECS, TLR7, RXFP3, DACT1, TRPV2, UBQLN1, UBQLN2, GPSM2, CXorf56, REEP1, TPK1, NOX1, NMNAT1, AGO2, CPEB1, HPGDS, ROBO3, TMEM97, NOD2, TRIB2, SLC39A8, GOLPH3, ACAD9, STRN4, MCOLN1, TRAPPC4, DCDC2, RNF20, KLHL7, TRPM7, TDP1, IARS2, VAC14, PRPF40A, SLC25A38, ANO1, AGGF1, ANO10, OSGEP, SLC30A10, DARS2, ASIC4, SHQ1, NDE1, TRPM4, PELI1, TMED9, ANO2, SLC17A7, TDP2, PDXP, ACKR3, UFM1, FAM20C, LGALS14, CD244, SUCLA2, ATP8A2, TREM2, RETREG1, CELF4, GTPBP2, STK33, SCNM1, METRN, KDM1A, SLC26A8, SMG1, SLC52A3, NMNAT2, ERC1, CDCA5, KIF1B, IQSEC2, FOXP2, CADPS2, SARM1, KANK1, MTG1, PMPCA, UBXN11, TNIK, NT5C2, SHANK3, SHANK2, WDR81, CANT1, JDP2, CNKSR2, LRRK2, NLGN1, RLN3, SLC16A10, MRGPRX4, WDR37, RPH3A, TRAK1, RAB3GAP1, MRGPRX3, GRIN3A, IL33, CNDP1, SLC52A2, EID1, QPCT, RNF19A, ARMC10, AKR1E2, NDEL1, WNT5B, POLDIP2, ABHD12, DGCR5, COL18A1, SRCIN1, SLC19A3, OPA3, UBA5, MUL1, CIZ1, FRRS1L, DDHD2, IBGC1, GPT2, BICD2, USP22, ATP13A2, SIRT5, ZNF469, CARD11, BRD4, SLC39A14, LPAR3, SETD3, SMUG1, SLITRK6, DAPK2, DTNBP1, AARS1, CXCL12, TNFRSF14, FGF2, FOXM1, FLNA, FOLH1, FRAXE, GABRA3, GABRG3, B4GALNT1, GAP43, GBA, GC, GCDH, GCHFR, GDF1, GGTA1P, GJB1, GLB1, GLRA2, GLUD1, GPI, FOXE1, FCN2, CXCR3, FABP7, DLX6, DNM1, DNM2, DPP4, DRD4, RCAN1, EBF1, ECM1, EDNRA, EEF1A2, ELK3, EMX2, EPHB1, EPHB2, ERBB4, ERCC2, ERG, ESR1, F2R, GPM6B, GPER1, RIPK1, HLA-DQB2, HMOX1, HNRNPA1, AGFG1, AGFG2, HRES1, HSPA9, HSPB1, HSPB2, HTC2, HTR2A, IDH3A, IDS, IDUA, IFNB1, IGF2, IL2, IL2RA, IL4, IL12A, HLA-DRB6, HLA-DQA1, GPR35, HLA-A, GPR42, GPX1, GPX4, GRIA2, GRIA3, GRIK1, GRIN2A, GRIN2D, GRM1, GRP, GRPR, GSK3B, H2AZ1, HSD17B10, HARS1, HCFC1, HCRTR2, HIP1, HK1, DLG4, DLD, NQO1, ANPEP, ANXA2, BIRC3, FAS, FASLG, ARNTL, ARSA, ASPA, ATP1A2, KIF1A, B2M, BACH1, BCS1L, BLM, DST, BRS3, BST2, BTN1A1, CACNA1D, CACNA1F, ANXA1, ANK3, CYB5R3, ALPL, ABCA1, ABCA2, ABO, ACR, ADAR, ADCYAP1, ADCYAP1R1, PARP1, ADRA1A, ADRA2B, GRK2, ADSL, AGER, JAG1, AGT, AGTR1, AHSG, ALDH3A2, ALOX15, CACNB4, CALB1, CALR, CAMK2B, COMP, COX15, CPE, CREBBP, CRK, CRMP1, CRYBB1, MAPK14, NCAN, CTLA4, CTSB, CYP1A2, CYP2B6, CYP2D6, CYP27A1, DARS1, DBH, DBN1, DCTN1, COL9A3, COL9A2, COL9A1, CD68, CAPN1, CAPN2, CAST, CASP6, CAV1, SERPINH1, CD1D, CD40LG, CDH13, CCR5, CDKN2A, CDKN2B, CEBPB, CEBPD, CHD2, ERCC8, CLCN2, CCR4, IL18, ILF2, CXCL10, SMARCA1, SNCG, SOD2, SPTAN1, SRY, SSTR4, STAT1, STAT3, ELOVL4, SULT1A1, VAMP1, TAC1, TBP, TERT, TGFBR2, TGM2, TH, THM, TIMP1, NKX2-1, SMARCA4, SLC22A4, NECTIN1, SLC6A2, QARS1, QDPR, RAB27A, RANBP2, RET, RGS4, RPA1, RPS27, S100A1, S100A6, SCN2A, CCL17, SFRP2, SLAMF1, SLC1A1, SLC1A3, SLC4A3, SLC2A4, SLC6A1, TLR2, TLR4, TMSB4X, CLEC3B, CXCR4, SCLC1, RAB7A, ST8SIA4, AIMP2, GAN, TAF15, AKAP1, FZD4, PLA2G10, ULK1, CUL1, SEMA7A, PIK3R3, DEGS1, KMO, TP63, PDE5A, BECN1, TUBA1A, ZIC2, YWHAZ, TXN, TNFAIP1, TPH1, TPO, TRPC3, TRPC6, TSC2, TTK, TWIST1, TXNRD1, YWHAG, UBB, UCP2, UTRN, VDAC1, VDR, VRK1, WNT1, XRCC1, ALDH18A1, PVR, INS, MITF, MME, MNAT1, MOV10, MPO, MST1R, COX1, ND6, MTR, RNR2, MYLK, NAGA, NCAM1, NDUFV1, NFKB1, NGFR, NQO2, NMT1, NOS2, NOVA2, ATXN3, MAP3K5, PURA, MEFV, INPPL1, ISG20, ITPR3, KCNJ5, KCNQ1, KIFC1, LEP, LIG4, LRPAP1, LTBP3, SH2D1A, LYZ, MAB21L1, MAG, MANBA, MAP1B, MDK, MEF2A, MEF2C, PNP, NPTX2, NRGN, NTF3, POLD2, POMC, PON1, PPARA, PPP2R2B, PPT1, PREP, PRF1, PRKCA, PRKCB, PRKD1, MAPK8, MAPK9, MAPK10, MAP2K7, EIF2AK2, HTRA1, PSMA1, PTX3, PMP22, PLA2G4A, PLA2G2A, PCSK2, DDR2, NTS, OGDH, OXA1L, P2RY6, PAK1, PRKN, PARN, PDE7A, PLA2G1B, PDGFB, PDGFRB, ENPP2, PDYN, SERPINF1, PEX1, PEX6, PITX3, STIN2-VNTR
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Hypotonic-Hyporesponsive Episode
Wikipedia
Hypotonic-hyporesponsive episode (HHE) Symptoms Hypotonia , hyporesponsiveness, pallor , cyanosis . [1] [2] Usual onset 1 minute to 48 hours post-vaccination. [1] Duration 1 minute to 14 days (median 10 hours). [1] Causes Vaccination , most commonly pertussis vaccine . [1] Diagnostic method Based on symptoms. [1] [3] Differential diagnosis Vasovagal syncope , seizure Prevention Those who experience an HHE after pertussis vaccination may avoid further pertussis vaccines. [1] [4] Treatment Usually resolves on its own, management involves checking the airway, breathing, and circulation, and hospitalization for observation and to rule out other conditions. [5] [1] [6] Deaths None reported A hypotonic-hyporesponsive episode (HHE) is defined as sudden onset of poor muscle tone , reduced consciousness , and pale or bluish skin occurring within 48 hours after vaccination , most commonly pertussis vaccination . [2] An HHE is estimated to occur after 1 in 4,762 to 1 in 1,408 doses of whole cell pertussis vaccine, and after 1 in 14,286 to 1 in 2,778 doses of acellular pertussis vaccine. [3] References [ edit ] ^ a b c d e f g "Hypotonic, hyporesponsive episode (HHE)" (PDF) . 7 January 2006 . Retrieved 2018-01-24 . ^ a b "Hypotonic–Hyporesponsive Episodes Reported to the Vaccine Adverse Event Reporting System (VAERS), 1996–1998 | ELECTRONIC ARTICLE" . Pediatrics . Retrieved 2018-01-22 . ^ a b "Hypotonic-hyporesponsive episode (HHE) as an adverse event following immunization in early childhood: Case definition and guidelines for data collection, analysis, and presentation | Jan Bonhoeffer" . Academia.edu . Retrieved 2018-02-01 . ^ "Pinkbook | Pertussis | Epidemiology of Vaccine Preventable Diseases" . CDC . Retrieved 2018-01-24 . ^ http://www.medsafe.govt.nz/profs/puarticles/8.htm ^ "Hypotonic–Hyporesponsive Episodes Reported to the Vaccine Adverse Event Reporting System (VAERS), 1996–1998 | ELECTRONIC ARTICLE" . Pediatrics . Retrieved 2018-01-24 .
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Logorrhea (Psychology)
Wikipedia
CCM Health . Archived from the original on 2018-04-10 . Retrieved 9 April 2018 . ^ Hallowell, Brooke (2008). ... Brain Injury Help . Archived from the original on 2018-04-10 . Retrieved 9 April 2018 . ^ Bogousslavsky J, Ferrazzini M, Regli F, Assal G, Tanabe H, Delaloye-Bischof A (January 1988). ... CCM Health . Archived from the original on 2018-04-10 . Retrieved 9 April 2018 . ^ "Clinical Management of Bipolar Disorder" . ... Archived from the original on 10 April 2018 . Retrieved 9 April 2018 . ^ "Logorrhea" . CCM Health . Archived from the original on 2018-04-10 . Retrieved 9 April 2018 .
