��pk10��-��360bet.net��-��1946-ope��-(��900bet.net��)-��pk10��-��pk10��-��ms88��-(��bet91.net��)

Advanced

FindZebra Summary is loading...

Organophosphate Poisoning Wikipedia

The effects of OP exposure on infants and children are at this time currently being researched to come to a conclusive finding. [12] [13] Evidence of OP exposure in pregnant mothers are linked to several health effects in the fetus. ... These syndromes result after acute and chronic exposure to OP pesticides. Cholinergic syndrome occurs in acute poisonings with OP pesticides and is directly related to levels of AChE activity. ... Paraoxonase ( PON1 ) is a key enzyme involved in OP toxicity and has been found to be critical in determining an organism's sensitivity to OP exposure. PON1 can inactivate some OPs through hydrolysis. PON1 hydrolyzes the active metabolites in several OP insecticides such as chlorpyrifos oxon, and diazoxon, as well as, nerve agents such as soman, sarin, and VX. ... Measurements of OP metabolites in both the blood and urine can be used to determine if a person has been exposed to organophosphates.

ACHE, BCHE, PEPD, PON1, GSR
Cryptogenic Organizing Pneumonia Orphanet

Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized pathologically by organizing pneumonia (OP) that presents with non-specific flu-like symptoms, as well as cough and dyspnea and where no etiological agent is found. ... Diagnostic methods Diagnosis is based on clinical picture, imaging, histopathology of the lung and the exclusion of all causes of secondary OP. High resolution computed tomographic scan reveals 3 main imaging patterns: multiple patchy alveolar opacities that may migrate (in the majority of cases; typical COP), a solitary focal nodule or mass (focal COP), or diffuse infiltrative opacities (infiltrative or progressive fibrotic COP). Video-assisted thoracoscopy is the method of choice in obtaining lung tissue but transbronchial biopsies, core needle biopsies, and recently transbronchial cryobiopsies are alternate methods. Hallmark histological findings of OP are patchy filling of the lung alveoli and respiratory bronchioles by buds of granulation tissue composed of fibroblasts and myofibroblasts (Masson bodies). ... Differential diagnosis The main differential diagnosis is idiopathic chronic eosinophilic pneumonia. Secondary OP must also be excluded by elimination of its possible causes, including primary biliary cirrhosis, ulcerative colitis, Crohn disease, Sweet syndrome, sarcoidosis, Behçet disease, primary pulmonary lymphoma, drugs, infections, and all connective tissue diseases, especially rheumatoid arthritis and idiopathic inflammatory myopathies.

UNC119, CD68, CRP, NR3C1, HDAC2, CXCL8, TNF, TNFRSF1A, TNFRSF1B, CD163, ING4, COP1, HT, TOMM5, WG, SFTPA1
- Bronchiolitis Obliterans Organizing Pneumonia GARD
  
  Bronchiolitis obliterans organizing pneumonia (BOOP) is a lung disease that causes inflammation in the small air tubes (bronchioles) and air sacs (alveoli). BOOP typically develops in individuals between 40-60 years old; however the disorder may affect individuals of any age. The signs and symptoms of BOOP vary but often include shortness of breath, a dry cough, and fever. BOOP can be caused by viral infections, various drugs, and other medical conditions. If the cause is known, the condition is called secondary BOOP. In many cases, the underlying cause of BOOP is unknown.
- Cryptogenic Organizing Pneumonia Wikipedia
  
  ., fevers , chills , night sweats , fatigue , weight loss) and respiratory (e.g. difficulty breathing , cough ) symptoms in association with filling of the lung alveoli that is visible on chest x-ray . [7] This presentation is usually so suggestive of an infection that the majority of patients with COP have been treated with at least one failed course of antibiotics by the time the true diagnosis is made. [7] Causes [ edit ] Pulmonary infection by bacteria , viruses and parasites Drugs : antineoplastic drugs , erlotinib , amiodarone Chemical exposure, most notably to diacetyl [8] Vaping : On October 17, 2019, the American Journal of Clinical Pathology reported that lung biopsies from patients with vaping-associated pulmonary illness show acute lung injury patterns, including organizing pneumonia. [9] Ionizing radiations [10] [11] Inflammatory diseases Systemic lupus Rheumatoid arthritis (RA-associated COP) Scleroderma Bronchial obstruction Proximal bronchial squamous cell carcinoma [12] SARS-CoV-2 Analysis of COVID-19 CT imaging along with postmortem lung biopsies and autopsies suggest that the majority of patients with COVID-19 pulmonary involvement also have secondary organizing pneumonia (OP) or its histological variant, acute fibrinous and organizing pneumonia, which are both well-known complications of viral infections. [13] It was identified in 1985, although its symptoms had been noted before but not recognised as a separate lung disease. ... "Radio-pathological correlation of organizing pneumonia (OP): a pictorial review" . The British Journal of Radiology . 90 (1071): 20160723. doi : 10.1259/bjr.20160723 .
- Cryptogenic Organizing Pneumonia GARD
  
  Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized by lung inflammation and scarring that obstructs the small airways and air sacs of the lungs (alveoli). Signs and symptoms may include flu-like symptoms such as cough, fever, malaise , fatigue and weight loss. COP often affects adults in midlife (40 to 60 years of age). The exact underlying cause of the condition is unknown (idiopathic). Treatment varies based on the severity of the condition but generally includes glucocorticoids .
Osteoporosis-Pseudoglioma Syndrome OMIM

Frontali and Dallapiccola (1986) likewise concluded that Beighton's ocular osteogenesis imperfecta is osteoporosis-pseudoglioma syndrome, and Beighton (1986) acknowledged the diagnosis. Teebi et al. (1988) described OPS in 2 brothers and a sister whose parents were phenotypically normal first cousins. ... Population Genetics From a review of published cases, Frontali et al. (1985) suggested that OPS may be more frequent in Mediterranean countries. Mapping Gong et al. (1996) analyzed 16 DNA samples (7 affected individuals) from 3 different consanguineous kindreds with OPS. Using a combination of traditional linkage analysis and homozygosity mapping, they assigned the OPS locus to 11q12-q13. ... Gong et al. (1996) found that the most likely location of the OPS gene is in a 3-cM region between GSTP1 (134660) and D11S1296.

LRP5, INPPL1, LRP6, SOST, FN1, GSTP1, LDLR, PTH, FGF19, TCIRG1, TSPAN12, DDX53
- Osteoporosis-Pseudoglioma Syndrome MedlinePlus
  
  Osteoporosis-pseudoglioma syndrome is a rare condition characterized by severe thinning of the bones (osteoporosis) and eye abnormalities that lead to vision loss. In people with this condition, osteoporosis is usually recognized in early childhood. It is caused by a shortage of minerals, such as calcium, in bones (decreased bone mineral density), which makes the bones brittle and prone to fracture. Affected individuals often have multiple bone fractures, including in the bones that form the spine (vertebrae). Multiple fractures can cause collapse of the affected vertebrae (compressed vertebrae), abnormal side-to-side curvature of the spine (scoliosis ), short stature, and limb deformities.
- Osteoporosis-Pseudoglioma Syndrome Orphanet
  
  Osteoporosis pseudoglioma syndrome is a very rare autosomal recessive disorder characterized by congenital or infancy-onset blindness and severe juvenile-onset osteoporosis and spontaneous fractures. Epidemiology The estimated prevalence is 1/2 000 000. Clinical description Additional clinical manifestations may include microphthalmos, abnormalities of the iris, lens or vitreous, cataracts, short stature, microcephaly, ligamental laxity, mental retardation and hypotonia. Etiology The disease is caused by mutations in the low-density lipoprotein receptor related protein 5 gene ( LRP5 ).
Pancreatic Neuroendocrine Tumor GARD

However in some cases, a pancreatic NET occurs outside of the pancreas. A NET arises from cells that produce hormones, so the tumor can also produce hormones. ... Pancreatic NETs are called either functional or nonfunctional. A functional pancreatic NET causes specific symptoms because it makes extra hormones, such as gastrin, insulin, or glucagon. ... Pancreatic NETs can be hard to diagnosis, often not identified until 5 to 10 years after they begin to grow. Most pancreatic NETs are not inherited and occur sporadically in people with no family history of NETs.

MEN1, PCSK1, ATM, BRCA2, C11orf65, IGF2, SST, TP53, CDKN2A, SLC6A2, MTOR, EPHB1, POMC, GH1, GCGR, DAXX, ELK3, KRT19, SSTR2, CHGA, SSTR5, UCHL1, FZD4, GCM2, DLGAP1, DCLK1, SSTR4, INA, STK11, EIF2AK3, TFE3, THBD, CXCR4, PAX8, TSC1, TTR, TYMS, VEGFA, ABO, CNPY2, MRGPRX4, GPR166P, VN1R17P, MIR196A1, GADL1, MRGPRX1, GPRC6A, OXER1, GPR119, GPR151, MRGPRX3, SEMA3A, AZIN2, ACCS, STK33, LGR6, ACSS2, MEG3, NEUROG3, LPAR3, LILRB1, PLA2G15, RET, SLC2A3, INSM1, GRN, FFAR1, GHRH, GAST, FGFR4, F3, EGFR, DHCR24, CSF1, CRH, CHGB, CD44, CCK, CALCA, VPS51, ATRX, ASS1, ASCL1, ANGPT2, HSF1, PDX1, SLC2A2, KIT, SLC2A1, SEA, SDHB, SDHA, AKT1, PYGM, PTH, PTEN, PPY, PTPA, PGR, PCYT1A, PCNA, NFKB1, NEUROD1, MUC1, SMAD4, STMN1, KRAS, H3P10
- Neuroendocrine Tumor Of Pancreas Orphanet
  
  Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma) (see these terms). Epidemiology Prevalence in the U.S. is estimated at 1/4,000-1/3,300 and 1/37,000 in Japan, but this is likely an underestimate due to a low detection rate. Clinical description PNETs, when functional, usually present in the 5th decade of life as various hypersecretion syndromes. These include insulinoma presenting with hyperinsulinemic hypoglycemia; glucagonoma with necrolytic migratory erythema, diabetes mellitus, and thomboembolisms; VIPoma with watery diarrhea, hypokalemia and or hypo/achlorhydia; SSoma with diabetes mellitus, cholelithiasis, steatorrhea and hypochlorhydria; and ZES with severe peptic ulcer disease.
Neuroendocrine Tumor GARD

A neuroendocrine tumor (NET) is a rare type of tumor that arises from specialized body cells called neuroendocrine cells . ... Pancreatic neuroendocrine tumors (also called islet cell tumors) - NETs that typically arise in the pancreas, although they can occur outside the pancreas. A p heochromocytoma is another, rarer type of NET that usually develops in the adrenal gland , but can also arise in other parts of the body. ... Functional NETs produce a specific set of symptoms due to the production of excess hormones, while non-functional NETs generally do not cause specific symptoms. In many cases, a person has no symptoms until the tumor spreads to the liver and/or impairs the function of an organ or system. This can make NETs very hard to diagnose. The majority of NETs are not inherited and occur sporadically in people with no family history of NETs.

PRKAR1A, MEN1, CALCA, RUNX1T1, CDKN1B, CGA, CHGA, FN1, GAST, IGFBP3, PTH, RET, ADAM17, QRSL1, CDC73
- Endocrine Gland Neoplasm Wikipedia
  
  Endocrine gland neoplasm Specialty Oncology , endocrinology An endocrine gland neoplasm is a neoplasm affecting one or more glands of the endocrine system . Examples include: Adrenal tumor Pituitary adenoma The most common form is thyroid cancer . [1] Condition such as pancreatic cancer or ovarian cancer can be considered endocrine tumors, or classified under other systems. Pinealoma is often grouped with brain tumors because of its location. [ citation needed ] See also [ edit ] Multiple endocrine neoplasia References [ edit ] ^ "Thyroid cancer" . Archived from the original on 2007-12-20 . Retrieved 2007-12-22 . External links [ edit ] Classification D ICD - 10 : C73 - C75 D34 - D35 MeSH : D00470 v t e Overview of tumors , cancer and oncology Conditions Benign tumors Hyperplasia Cyst Pseudocyst Hamartoma Malignant progression Dysplasia Carcinoma in situ Cancer Metastasis Primary tumor Sentinel lymph node Topography Head and neck ( oral , nasopharyngeal ) Digestive system Respiratory system Bone Skin Blood Urogenital Nervous system Endocrine system Histology Carcinoma Sarcoma Blastoma Papilloma Adenoma Other Precancerous condition Paraneoplastic syndrome Staging / grading TNM Ann Arbor Prostate cancer staging Gleason grading system Dukes classification Carcinogenesis Cancer cell Carcinogen Tumor suppressor genes / oncogenes Clonally transmissible cancer Oncovirus Carcinogenic bacteria Misc. Research Index of oncology articles History Cancer pain Cancer and nausea v t e Tumours of endocrine glands Pancreas Pancreatic cancer Pancreatic neuroendocrine tumor α : Glucagonoma β : Insulinoma δ : Somatostatinoma G : Gastrinoma VIPoma Pituitary Pituitary adenoma : Prolactinoma ACTH-secreting pituitary adenoma GH-secreting pituitary adenoma Craniopharyngioma Pituicytoma Thyroid Thyroid cancer (malignant): epithelial-cell carcinoma Papillary Follicular / Hurthle cell Parafollicular cell Medullary Anaplastic Lymphoma Squamous-cell carcinoma Benign Thyroid adenoma Struma ovarii Adrenal tumor Cortex Adrenocortical adenoma Adrenocortical carcinoma Medulla Pheochromocytoma Neuroblastoma Paraganglioma Parathyroid Parathyroid neoplasm Adenoma Carcinoma Pineal gland Pinealoma Pinealoblastoma Pineocytoma MEN 1 2A 2B This article about a neoplasm is a stub .
Neuroendocrine Tumor Wikipedia

H&E stain Specialty Endocrine oncology Neuroendocrine tumors ( NETs ) are neoplasms that arise from cells of the endocrine ( hormonal ) and nervous systems . ... G1 and G2 neuroendocrine neoplasms are called neuroendocrine tumors (NETs) – formerly called carcinoid tumours. ... Unsourced material may be challenged and removed. ( November 2015 ) ( Learn how and when to remove this template message ) NETs from a particular anatomical origin often show similar behavior as a group, such as the foregut (which conceptually includes pancreas, and even thymus, airway and lung NETs), midgut and hindgut ; individual tumors within these sites can differ from these group benchmarks: Foregut NETs are argentaffin negative. ... Bone metastasis is uncommon. Hindgut NETs are argentaffin negative and rarely secrete 5-HT, 5-HTP, or any other vasoactive peptides. ... Not all cells are immediately killed; cell death can go on for up to two years. [ citation needed ] PRRT was initially used for low grade NETs. It is also very useful in more aggressive NETs such as Grade 2 and 3 NETs [83] [84] provided they demonstrate high uptake on SSTR imaging to suggest benefit.

MEN1, CDKN1B, SSTR2, DAXX, ATRX, BRAF, TYMS, PTHLH, SSTR3, SSTR1, BAP1, MTOR, SST, GAST, SLC6A2, INSM1, CTNNB1, RET, PIK3CA, DNMT3A, POMC, EPHB1, PIK3CG, PIK3CD, CHGA, ELK3, CHEK2, PIK3CB, GRN, CD274, SMUG1, AKT1, GNA12, TP53, SYP, VEGFA, CDKN2A, ASCL1, BCL2, ENO2, NCAM1, GCG, MYCN, EGFR, MGMT, KIT, RASSF1, VHL, SCLC1, SSTR5, FOLH1, NKX2-1, KRAS, CALCA, CCND1, TAC1, PTPRF, VIP, NTS, PAX5, RHBDF2, GRP, IGF1, SDHD, GOT1, MAP2K7, CCK, ERBB2, DLL3, PPY, CXCL12, TP63, SMAD4, MUC1, INS, GCGR, CKAP4, NEUROD1, ISL1, MYC, NGF, SATB2, GLP1R, HSP90AA1, H3P10, HRAS, CHGB, CALR, NTRK1, TEK, DLK1, CDK4, CDX2, TGFA, UCHL1, RPE65, PGR, PDGFRA, CARTPT, CRH, UVRAG, SLC5A5, CXCR4, IGF1R, OTP, IL6, PHLDA3, TTF1, PAX8, TACR1, STK11, TRIM21, PLA2G15, SCG2, SQLE, SLC18A2, TERT, HDAC9, SLC2A1, PROM1, BCL2L11, NTSR1, PAX6, NAMPT, NOCT, INA, PLCB3, CD200, MKI67, PDX1, MAPK1, NES, HPSE, PTEN, STMN1, ABO, RIPK1, RORC, RAF1, IL1B, TRPV1, GATA3, ANGPT2, FOXM1, PTK2B, SDHAF2, ACCS, BDNF, EPAS1, EGF, ACSS2, MIB1, DNMT1, CCN2, TRPM8, CLDN4, CPE, CD34, CD44, FLNA, CEACAM5, B3GAT1, GH1, GIP, GHSR, GIPR, ADCY2, ALB, H3P28, TPPP2, H4C5, GGH, MIR1290, TMEM209, ELOA3, H4C13, H4C14, GPR151, SRPX, LGR5, TNFSF11, PSMG1, DCBLD2, H4-16, NRP1, MRGPRX4, SOCS1, H4C2, MIR3137, MRGPRX3, TNFRSF25, H3P12, CYYR1, AZIN2, DNER, AK6, MLIP, LMLN, NRP2, GPR68, MIR1246, H4C8, MAFK, MIR150, MIR155, MBOAT4, H4C9, MIR21, POTEKP, VN1R17P, SNORD95, GPR166P, ARID1A, EID3, SLC7A5, MIR375, H4C15, FZD4, MIRLET7C, OXER1, H4C12, HMGA2, H4C3, ARX, ELOA3B, GPRC6A, H4C11, H4C6, C17orf97, POTEM, MRGPRX1, ARMH1, H4C1, GADL1, ACTBL2, H4C4, BRI3, SQSTM1, ISYNA1, GHRL, ACOT7, KLF12, KRT20, SLC27A4, TET2, BCOR, EBNA1BP2, RALBP1, PGRMC1, LAMTOR1, FBXW7, MEG3, MAML3, TMEM127, NTNG1, ATRAID, KHDRBS1, DCTN4, SNORD61, NUP62, SNORD48, NTSR2, LPAR3, MAPK8IP2, SRRM2, BRD4, TRAM1, SPINK4, XIST, PPWD1, RBMS3, SETD1B, ZHX2, TNFSF13B, USE1, MAK16, UBE2Z, ONECUT2, FHL5, GCM2, DCLK1, ZBED1, ARHGEF2, PALB2, ALG9, SNED1, TET1, PDCD1LG2, TMPRSS13, MTA1, RPAIN, H1-10, EEF1E1, LGR6, PRMT5, NEUROD4, YAP1, SCML2, LANCL1, PAK4, RABEPK, ZNF197, CTNNBL1, PNO1, INSL5, EPB41L5, HDAC5, AKT3, CD302, GBA3, DCAF1, ATAT1, SERPINA3, VCL, CGA, ESR1, ERBB4, EPHB2, E2F1, DUSP2, DSG3, DPT, DPP4, DMBT1, DDC, DAD1, VCAN, CREB1, CRABP1, KLF6, CLU, FOXN3, CEACAM7, CEACAM3, ESR2, ETFA, EZH2, GHRH, HSPA4, AGFG1, HMOX1, HMGA1, GTF2H1, GSN, GNAS, GNA15, GFRA1, F3, GDNF, FSHR, FLT4, FLII, FLI1, FOXO1, FHIT, FGFR4, CGB3, CFL1, UQCRFS1, CDKN2C, FAS, APRT, APLP1, XIAP, APC, SLC25A6, SLC25A4, ANGPT1, ALK, AKT2, AFP, PARP1, ADCYAP1R1, ADCYAP1, ACVRL1, ACTN4, ACTG2, ACTG1, ACR, AQP4, ARF1, ATM, CASP3, CDK6, CD40LG, CD36, CD33, CCNE1, CCKBR, SERPINA6, CAV1, CA9, ATOH1, VPS51, C5, BRS3, BRCA2, DST, BAX, AVP, ATP4A, HTC2, HTR2A, TNC, IAPP, SDC1, SCT, SORT1, RNASE3, RARB, PTPRZ1, PTPRM, PTBP1, PSMD7, PSG2, PRKAR1A, PPP4C, POU4F1, PNN, PKD2, PITX2, PCYT1A, SERPINA5, PAX4, SDCBP, SDHB, SDHC, ST2, UBE2I, TPM3, TPH1, TNF, TM7SF2, TERC, TAT, STAT3, SSTR4, SEMA3F, SSR2, SOX11, SOX4, SOX2, SLPI, SLC3A2, SLC1A5, SFRP1, PAK3, PAK1, TNFRSF11B, KIF11, MDK, MAOA, LCN2, RPSA, L1CAM, KRT19, KRT7, KRT5, IL12A, MET, IL9, CXCL8, IL2, IL1A, IGFBP1, IGF2, IFNA13, IFNA1, MDM2, MFAP1, ODC1, MUTYH, NTRK2, NT5E, NRAS, NOTCH3, NPY, NOTCH1, NFKB1, NEFM, MUC4, CD99, NUDT1, COX2, MTAP, MST1R, MST1, MSMB, MMP7, MLH1, PTPRC
- Neuroendocrine Tumors Mayo Clinic
  
  Overview Neuroendocrine tumors are cancers that begin in specialized cells called neuroendocrine cells. Neuroendocrine cells have traits similar to those of nerve cells and hormone-producing cells. Neuroendocrine tumors are rare and can occur anywhere in the body. Most neuroendocrine tumors occur in the lungs, appendix, small intestine, rectum and pancreas. There are many types of neuroendocrine tumors. Some grow slowly and some grow very quickly. Some neuroendocrine tumors produce excess hormones (functional neuroendocrine tumors).
Deafness With Anhidrotic Ectodermal Dysplasia OMIM

Clinical Features Helweg-Larsen and Ludvigsen (1946) reported a kindred of 14 in 5 generations with anhidrosis, 5 of whom had defective hearing with onset between 35 and 45 years of age. ... Inheritance There were several instances of father-son transmission in the family reported by Helweg-Larsen and Ludvigsen (1946), suggesting autosomal dominant inheritance.
Coinfection Wikipedia

Global prevalence or incidence of coinfection among humans is unknown, but it is thought to be commonplace, [1] sometimes more common than single infection. [2] Coinfection with helminths affects around 800 million people worldwide. [3] Coinfection is of particular human health importance because pathogen species can interact within the host. The net effect of coinfection on human health is thought to be negative. [4] Interactions can have either positive or negative effects on other parasites. ... PMID 10386428 . ^ Griffiths, EC; Pedersen, ABP; Fenton, A; Petchey, OP (2011). "The nature and consequences of coinfection in humans" .

GPT, IL10, TNF, IFNA1, IFNA13, IL1B, MBL2, ATAD1, IL6, TLR4, S100A8, NLRP3, IFNG, CRP, TLR2, TMPRSS13, MSMB, MPO, TCN1, MST1, LMLN, CRYL1, GLUD1, UGDH, MYD88, PTPN11, LPL, ALB, H6PD, TP53, CXCL10, UBE2B, STIL, IVNS1ABP, MMP1, TLR9, PMEL, IFNA2, IFNB1, IL2, CXCL8, IL17A, KLRC2, EXT1, SMOX, PDLIM7, ARG1, CACNA1B, BMPER, BRCA1, IL33, CCR5, LINC01194, CD14, MIR146A, CCL2, DEFB4A, AFP, LXN, DEFB4B, COPD, SOAT1, SNAP25, HACD1, SMARCB1, ST13, ST14, IL32, IL1RL1, FCGR2C, STXBP1, HSP90B1, SULT2A1, TAP1, TPO, TPI1, TLR3, UTRN, ZAP70, CXCR4, SLBP, NR4A3, BCAR3, TIMP4, DENR, TGM3, TGFB1, PRDX2, TNFSF10, PROM1, CD163, ARTN, NAT2, PPIG, TICAM1, HAMP, SRR, ERVK-6, MRPL41, RNF34, DNAJC5, UBASH3B, TSLP, HPS4, TRIM69, NLRP6, GDF15, IFNL3, VN1R2, VN1R4, VN1R5, TREML1, MIR20B, KLKP1, CCR2, TRAP, AD12, PGPEP1, RHOF, IER3IP1, HEBP1, TP53I3, APOBEC3B, STAM2, TRIM22, TACC3, SORBS1, C1QL1, METAP2, NT5C2, BRD4, SEC14L2, SUMF2, PARS2, IL17C, PRSS50, RMC1, OBP2A, ERVW-1, IL22, MBL3P, NTM, CAP1, PPARG, CXCL12, F12, DECR1, DHCR7, DHFR, DPP4, E2F1, EGR1, ELANE, ELAVL1, EPHA3, EPRS1, F8, FCGR3A, CXCL11, FCGR3B, FGF2, FGF9, FLNA, GAPDH, CBLIF, GJA1, GLB1, GRN, CXCL1, HDLBP, DAPK1, CYP26A1, CYP3A4, CYP2B6, ACTB, AGRP, AHR, AKT1, AMBP, ANXA6, AZU1, BCL2, OPN1SW, CFB, BMP1, CAV2, CD33, CD38, ENTPD1, CEACAM5, CEACAM3, CEACAM7, CHAT, CHML, COX8A, CRH, CTAA1, CFH, HLA-B, HLA-DQB1, OAS1, PCNA, PF4, SLC25A3, SERPINA1, SERPINB6, SERPINB9, PIK3CA, PIK3CB, PIK3CD, PIK3CG, ABCA1, PRCP, MAP2K1, EIF2AK2, PSEN1, PSG2, PSMB8, PTPN2, RAD51, RAG1, RTN2, SCD, CCL5, SERPINE1, NM, HLA-G, NFKB1, HMOX1, FOXA2, HSPA4, IFNA4, IFNAR2, IL1A, IL4, IL15, IL18, IRF3, ITGA2B, ITPA, KLKB1, KIF22, LNPEP, LTF, LYZ, MBP, CXCL9, MMP9, MUC2, NDUFS3, NFE2L2, ERVK-20
Party And Play Wikipedia

'Social media and drug markets', The internet and drug markets (European Monitoring Centre for Drugs and Drug Addiction: Insights 21), Publications Office of the European Union, Luxembourg. v t e Lesbian , gay , bisexual , and transgender ( LGBT ) slang List Ace Bareback Banjee Bear Beard Beat Bi-curious Boi Top, bottom and versatile Bottom surgery Breeder Bugchasing Bulldagger Butch Castro clone Chicken Chickenhawk Chub Chubby chaser Cottaging Cruising Daddy Down-low Drag Dyke En femme En homme Fag (Faggot) Fag hag Fag stag Faux queen F2M Femme Flagging (hanky code) Friend of Dorothy Fruit Fruit fly Gay-for-pay Gaydar Gaymer Genderfuck Gold star lesbian Glory hole Heteroflexibility Lesbian until graduation Lipstick lesbian M2F Non-op Packing Party and play Passing Poppers Post-op Pre-op Queen RLE Shemale Soft butch Scissoring SRS Stone butch Stealth Swish T Tea-room TERF Top surgery Trache shave Trade Tranny Transfan Transition Tribbing Troll Twink U-Haul lesbian Womyn-born womyn Related Polari LGBT linguistics Terminology of homosexuality Category v t e Methamphetamine Enantiomers Dextromethamphetamine Levomethamphetamine Neuropharmacology Biomolecular targets TAAR1 (agonist) σ1R (agonist) σ2R (agonist) α 2A adrenoceptor (agonist) α 2B adrenoceptor (agonist) α 2C adrenoceptor (agonist) MAO ( competitive inhibitor ) Inhibited transporters DAT NET SERT VMAT1 VMAT2 EAAT1 EAAT2 SLC22A3 SLC22A5 Health Amphetamine dependence Meth mouth Prenatal methamphetamine exposure History and culture Amphetamine Crystal Darkness Crystal Meth Anonymous Faces of Meth History and culture of amphetamines Montana Meth Project No More Sunsets Party and play Rolling meth lab Ya ba Law Legal status Combat Methamphetamine Epidemic Act of 2005 Comprehensive Methamphetamine Control Act of 1996 Illinois Methamphetamine Precursor Control Act Ethnicity and nationality United States Native Americans Australia v t e Sexual slang General Anilingus Banjee Bareback Baseball metaphors for sex Blue balls Bottom Camel toe Chickenhead Circle jerk Cock tease Cornhole Cougar Cunt Deep-throating Dick Dirty Sanchez Dogging Donkey punch Douche Felching Fuck Girlfriend experience Glory hole Hogging Hot Karl Italian profanity Latin profanity Mama-san Mammary intercourse Mat Mile high club Motherfucker Nookie Party and play Pearl necklace Pegging Pirate Pussy Quickie Red wings Rusty trombone Serosorting Shemale Slut Snowballing Soggy biscuit Switch Teabagging Tits Top Top, bottom and versatile Turkey slap Twat Voulez-vous coucher avec moi?
Postural Orthostatic Tachycardia Syndrome Due To Net Deficiency Orphanet

A rare, genetic, primary orthostatic disorder characterized by dizziness, palpitations, fatigue, blurred vision and tachycardia following postural change from a supine to an upright position, in the absence of hypotension. A syncope with transient cognitive impairment and dyspnea may also occur. The norepinephrine transporter deficiency leads to abnormal uptake and high plasma concentrations of norepinephrine.

SLC6A2, SLC12A2
- Orthostatic Intolerance Wikipedia
  
  Human disease Orthostatic intolerance ( OI ) is the development of symptoms when standing upright which are relieved when reclining . [1] There are many types of orthostatic intolerance. OI can be a subcategory of dysautonomia , a disorder of the autonomic nervous system [2] occurring when an individual stands up. [3] There is a substantial overlap between syndromes of orthostatic intolerance on the one hand, and either chronic fatigue syndrome (CFS) or fibromyalgia (FM) on the other. [4] It affects more women than men (female-to-male ratio is at least 4:1), usually under the age of 35. [5] Orthostatic intolerance occurs in humans because standing upright is a fundamental stressor and requires rapid and effective circulatory and neurologic compensations to maintain blood pressure , cerebral blood flow , and consciousness . When a human stands, approximately 750 mL of thoracic blood is abruptly translocated downward. People who suffer from OI lack the basic mechanisms to compensate for this deficit. [1] Changes in heart rate , blood pressure, and cerebral blood flow that produce OI may be caused by abnormalities in the interactions between blood volume control, the cardiovascular system , the nervous system and circulation control system . [6] Contents 1 Signs and symptoms 1.1 Acute OI 1.2 Chronic OI 2 Causes 3 Diagnosis 4 Management 5 Notable case 6 See also 7 References 8 External links Signs and symptoms [ edit ] Orthostatic intolerance is divided, roughly based on patient history, in two variants: acute and chronic . Acute OI [ edit ] Patients who suffer from acute OI usually manifest the disorder by a temporary loss of consciousness and posture , with rapid recovery (simple faints , or syncope ), as well as remaining conscious during their loss of posture.
- Postural Orthostatic Tachycardia Syndrome Wikipedia
  
  Not to be confused with Pott disease . Condition in which a change from lying to standing causes an abnormally large increase in heart rate Postural orthostatic tachycardia syndrome Other names Postural tachycardia syndrome (POTS) Specialty Cardiology , Neurology Symptoms More often with standing: lightheadedness , trouble thinking , tachycardia , weakness, [1] palpitations , heat intolerance , acrocyanosis Usual onset Most common (modal) age of onset is 14 years [2] Duration > 6 months [3] Causes Antibodies against the Alpha 1 adrenergic receptor [4] [5] [6] Risk factors Family history [1] Diagnostic method An increase in heart rate by 30 beats/min with standing [1] Differential diagnosis Dehydration , heart problems, adrenal insufficiency , epilepsy , parkinson disease [7] Treatment Avoiding factors that bring on symptoms, increasing dietary salt and water, compression stockings , exercise, medications [1] Medication Beta blockers , Ivabradine , midodrine , and fludrocortisone . [1] Prognosis ~90% improve with treatment, [8] 25% of patients unable to work [9] Frequency ~ 500,000 (US) [7] Postural orthostatic tachycardia syndrome ( POTS ) is a condition in which a change from lying to standing causes an abnormally large (or higher than normal) increase in heart beat rate . [1] This occurs with symptoms that may include lightheadedness , trouble thinking, blurred vision , or weakness. [1] Other commonly associated conditions include Ehlers–Danlos syndrome , mast cell activation syndrome , irritable bowel syndrome , insomnia , chronic headaches , chronic fatigue syndrome , and fibromyalgia . [1] Contents 1 Causation 2 Signs and symptoms 2.1 Brain fog 3 Causes 3.1 Autoimmunity 3.2 Secondary 4 COVID-19 5 Diagnosis 5.1 Diagnostic criteria 5.2 Autoantibodies against G-protein coupled receptor 5.3 Orthostatic intolerance 5.4 Differential diagnoses 6 Treatment 6.1 Medication 7 Prognosis 8 Epidemiology 9 History 10 Notable cases 11 References 12 Further reading 13 External links Causation [ edit ] The causes of POTS are varied. [10] Often, it begins after a viral infection, surgery, or pregnancy. [8] Risk factors include a family history of the condition. [1] Diagnosis in adults is based on an increase in heart rate of more than 30 beats per minute within ten minutes of standing up that is accompanied by symptoms. [1] Low blood pressure with standing , however, does not occur. [1] Other conditions which can cause similar symptoms, such as dehydration , heart problems, adrenal insufficiency , epilepsy , and parkinson disease , must not be present. [7] Treatment may include avoiding factors that bring on symptoms, increasing dietary salt and water, small and frequent meals, [11] avoidance of immobilization, [11] compression stockings , exercise program, and medications. [12] [13] [1] [14] Medications used may include beta blockers , [15] pyridostigmine , [16] midodrine [17] or fludrocortisone . [1] More than 50% of people whose condition was triggered by a viral infection get better within five years. [8] About 80% have symptomatic improvement with treatment, but 25 percent of patients are still unable to work. [9] [8] Retrospective studies has shown that five years after diagnosis 19% had a full resolution of symptom. [18] It is estimated that 500,000 people are affected in the United States. [19] The average age of onset is 20 years old, and it occurs about five times more frequently in females. [1] Signs and symptoms [ edit ] In adults the primary symptom is an increase in heart rate of more than 30 beats per minute within ten minutes of standing up. [1] [20] The resulting heart rate is typically more than 120 beats per minute. [1] For people aged between 12 and 19, the minimum increase for diagnosis is 40 beats per minute. [21] This symptom is known as orthostatic (upright) tachycardia (fast heart rate). It occurs without any coinciding drop in blood pressure, as that would indicate orthostatic hypotension . [20] Certain medications to treat POTS may cause orthostatic hypotension. It is accompanied by other features of orthostatic intolerance —symptoms that develop in an upright position and are relieved by reclining. [20] These orthostatic symptoms include palpitations , light-headedness , chest discomfort, shortness of breath , [20] nausea, weakness or "heaviness" in the lower legs, blurred vision , and cognitive difficulties. [1] Symptoms may be exacerbated with prolonged sitting, prolonged standing, alcohol, heat, exercise, or eating a large meal. [ citation needed ] In up to one third of people with POTS, [1] fainting occurs in response to postural changes or exercise. [22] Migraine -like headaches are common, sometimes with symptoms worsening in an upright position ( orthostatic headache ). [22] 40-50% of patients with POTS develop acrocyanosis of extremities, a reddish-purple color in the legs and/or hands when they stand (indicative of blood pooling). [23] [22] [24] 48% of people with POTS report chronic fatigue and 32% report sleep disturbances . [25] [26] [27] [28] Others exhibit only the cardinal symptom of orthostatic tachycardia. [22] Additional symptoms are varied, and may include excessive sweating, a lack of sweating, heat intolerance, digestive issues such as bloating, nausea, indigestion, constipation, and diarrhea, a flu-like feeling, coat-hanger pain, forgetfulness, brain fog, and presyncope . [29] Brain fog [ edit ] One of the most disabling and prevalent symptoms in POTS is " brain fog ", [30] a term used by patient to describe the cognitive difficulties they experience. In one survey of 138 POTS patients, brain fog was defined as “forgetful” (91%), “difficulty thinking” (89%), and “difficulty focusing” (88%). Other common description was "Difficulty processing what others say" (80%), Confusion (71%), Lost (64 %), and "Thoughts moving too quickly" (40%) [31] The same survey described the most common triggers of brain fog to be fatigue (91%), lack of sleep (90%), prolonged standing (87%) and dehydration (86%). [ citation needed ] Neuropsychological testing has shown that a POTS-patient has reduced attention (Ruff 2&7 speed and WAIS-III digits forward), short-term memory ( WAIS-III digits back), cognitive processing speed ( Symbol digits modalities test ) and executive function ( Stroop word color and trails B ). [32] [33] [34] A potential cause for brain fog is a decrease in cerebral blood flow (CBF), especially in upright position. [35] [36] [37] Another theory is that interoception of excessive autonomic activity causes interoceptive prediction errors (PE) to occur. [38] A prediction error is the mismatch between a prior expectation and reality. [39] This would cause anxiety which then overwhelms the consciousness of pots-patient causing cognitive-affective symptoms.
- Orthostatic Intolerance OMIM
  
  A number sign (#) is used with this entry because of evidence that orthostatic intolerance is caused by heterozygous mutation in the gene encoding the norepinephrine transporter (SLC6A2; 163970) on chromosome 16q12. One such family has been reported. Clinical Features Orthostatic intolerance is a syndrome characterized by adrenergic symptoms that occur when an upright posture is assumed: the heart rate increases by at least 30 beats per minute, without orthostatic hypotension (Jacob et al., 1997). Most patients with orthostatic intolerance are women between the ages of 20 and 50 years (Low et al., 1995). This syndrome, first described by Da Costa (1871), has been called soldiers heart (Fraser and Wilson, 1918), neurocirculatory asthenia (Wooley, 1976), and mitral valve prolapse syndrome (Boudoulas et al., 1980). It is similar in many respects to chronic fatigue syndrome (Schondorf and Freeman, 1999).
Neuroendocrine Neoplasm Of Esophagus Orphanet

A group of esophageal epithelial neoplasms characterized by neuroendocrine differentiation, comprising well-differentiated neuroendocrine tumors (NETs), poorly differentiated neuroendocrine carcinomas (NECs), and mixed neuroendocrine-non-neuroendocrine neoplasms, an umbrella category including mixed adenoneuroendocrine carcinoma. ... NECs may also arise in other parts of the esophagus. On endoscopy, NETs usually appear as small polypoid or nodular submucosal masses, while NECs are large, infiltrative, and ulcerated. Patients most commonly present with dysphagia, pain, weight loss, and sometimes melena. Metastatic NETs may be associated with carcinoid syndrome.
Arteries, Anomalies Of OMIM

Gates (1946) cited a family in which the grandfather showed bilaterally a radial artery that passed over the supinator longus muscle 3 to 4 cm above the wrist and ran over the radial extensors above the styloid process. ... This was clearly the family cited by Gates (1946). Inheritance - Autosomal dominant Vascular - Abnormal radial, ulnar, or interosseous artery ▲ Close
Idiopathic Interstitial Pneumonia Wikipedia

There are seven recognized distinct subtypes of IIP. [2] Contents 1 Diagnosis 2 Development 3 References 4 External links Diagnosis [ edit ] Classification can be complex, [3] and the combined efforts of clinicians , radiologists , and pathologists can help in the generation of a more specific diagnosis. [4] [5] Idiopathic interstitial pneumonia can be subclassified based on histologic appearance into the following patterns: [6] [7] Histology Clinical Correlates Desquamative interstitial pneumonia (DIP) DIP Diffuse alveolar damage (DAD) ARDS , AIP , TRALI Nonspecific interstitial pneumonia (NSIP) NSIP Respiratory bronchiolitis RB-ILD Usual interstitial pneumonia (UIP) CVD , IPF , drug toxicity , pneumoconiosis Organizing pneumonia Cryptogenic organizing pneumonia Lymphoid interstitial pneumonia (LIP) LIP Usual interstitial pneumonia is the most common type. [8] Development [ edit ] Table 1: Development of the (histologic) idiopathic interstitial pneumonia classification Leibow et al. (1969) Katzenstein (1998) [9] ATS/ERS (2002) [7] UIP UIP UIP DAD DAD NSIP NSIP DIP DIP/RB DIP RB BIP OP OP LIP ( LPD ) LIP GIP (HMF) (HMF) UIP=usual interstitial pneumonia; DAD=diffuse alveolar damage; NSIP=non-specific interstitial pneumonia; DIP=desquamative interstitial pneumonia; RB=respiratory bronchiolitis; BIP=bronchiolitis obliterans interstitial pneumonia; OP=organizing pneumonia; LIP=lymphoid interstitial pneumonia; LPD= lymphoproliferative disease (not considered a diffuse lung disease); GIP= giant cell interstitial pneumonia ; HMF=heavy metal fibrosis, no longer grouped with diffuse lung disease Lymphoid interstitial pneumonia was originally included in this category, then excluded, then included again. [10] References [ edit ] ^ Richard K.

IL13, IL4, MUC5B, MUC1, SFTPC, HNF4A, SFTPD, FAM13A, CD163, RECK, CXCR4, NKX2-1, USF2, TIAL1, THBD, TGFB1, TERT, TERC, CXCL13, ANGPT2, POSTN, SELE, SRRM2, RBMS3, FOXP3, PI15, RTEL1, TLR9, PNO1, MAK16, RTKN2, MUC21, SFTPA1, PSIP1, SDC4, CXCL12, IL13RA2, CD34, CHI3L1, CRP, VCAN, CCN2, DCN, DSG3, EGFR, ELANE, HNRNPD, IFNG, IL4R, MPO, BMP3, NCL, OVGP1, SERPINE1, PARN, PCBP2, PPARG, PTBP1, PTEN, PTPRC, CCL2, CCL7, CCL18, SFTPA2
Familial Gastric Type 1 Neuroendocrine Tumor Orphanet

A rare neoplastic disease characterized by occurrence of atypical and aggressive gastric type 1 neuroendocrine tumors (NET) in early adulthood. The tumors often show nodal infiltration requiring total gastrectomy. ... Patients present high serum gastrin concentrations and iron-deficiency anemia (rather than megaloblastic anemia, which is a typical feature in patients with sporadic gastric type 1 NET, where the tumor usually arises on the background of autoimmune atrophic gastritis).
X-Linked Congenital Stationary Night Blindness GeneReviews

Electroretinogram Findings in Complete and Incomplete X-Linked Congenital Stationary Night Blindness View in own window ERG Finding Complete ( NYX X-linked CSNB) Incomplete ( CACNA1F X-linked CSNB) Scotopic rod b-wave Severely reduced or absent Reduced Mixed scotopic a-wave Normal Slightly reduced Mixed scotopic b-wave Reduced Reduced Scotopic OP Absent Slightly reduced Photopic a-wave Normal, slightly reduced, sawtooth (square) shaped Reduced Photopic b-wave Slightly reduced Reduced Photopic OP Lost, except for OP4 All OPs are lost. 30-Hz flicker Normal / slightly reduced Reduced w/double peak OP = oscillatory potential Note: Pupillary responses have been described in the literature and in textbooks as "paradoxic" (i.e., miosis of pupils when lights are turned off, as opposed to dilation). ... X-linked CSNB should be suspected in a female proband with the following ERG findings (observed in some heterozygous females): Reduced oscillatory potentials (OPs) associated with rod activity [Rigaudière et al 2003] Reduced b-wave amplitudes (with unaffected OPs) in one heterozygous female [Rigaudière et al 2003] Establishing the Diagnosis Male proband.

CACNA1F, NYX, PDE6B, LRIT3, SLC24A1, SAG, RHO, GPR179, GNB3, GRM6, GNAT1, TRPM1, TIMP1, OTC, CNGA3, DYNLT3, RP2, MYBPC1, NR2E3, MAPRE3, CRB1, CABP4, PLXNA2, SEC16B, DMD, RPGR
Blackwater Fever Wikipedia

Cultural references [ edit ] Out of Africa , a 1985 film based on the experiences of author Isak Dinesen The Power of One , a 1992 film based on the book of the same name The Bridge on the River Kwai , a 1957 film about prisoners of war in a jungle environment At Play in the Fields of the Lord , a 1965 novel by Peter Matthiessen West with the Night (1942), African memoir by aviator Beryl Markham Burmese Days , a 1934 novel by George Orwell ; several associates of Flory are noted to have died of blackwater fever in chapter 5 Showdown , a 1946 novel by Errol Flynn The Heart of the Matter , a 1948 novel by Graham Greene Green Hills of Africa , a 1935 novel by Ernest Hemingway The Book of Secrets , a 1994 novel by M. ... External links [ edit ] Classification D ICD - 10 : B50 ICD - 9-CM : 084.8 MeSH : D001742 DiseasesDB : 7751 v t e Malaria Biology Malaria Cerebral Quartan fever Blackwater fever Pregnancy-associated Plasmodium biology life cycle vivax falciparum ovale malariae knowlesi Anopheles mosquito Lifecycle Schizont Merozoite Hypnozoite Gametocyte Control and prevention Public health DDT Mosquito net Malaria prophylaxis Mosquito control Sterile insect technique Genetic resistance Duffy antigen Sickle-cell anaemia Thalassemia G6PDH deficiency Malaria vaccine RTS,S Diagnosis and treatment Diagnosis of malaria Malaria culture Blood film Malaria antigen detection tests Antimalarials Artemisinin Mefloquine Proguanil Society and malaria Diseases of poverty Millennium Development Goals History of malaria Roman fever National Malaria Eradication Program World Malaria Day Epidemiology Malaria and the Caribbean Malaria Atlas Project Organisations Malaria Consortium Against Malaria Foundation Bill & Melinda Gates Foundation Imagine No Malaria Malaria No More Africa Fighting Malaria African Malaria Network Trust South African Malaria Initiative African Leaders Malaria Alliance Amazon Malaria Initiative The Global Fund to Fight AIDS, Tuberculosis and Malaria Medicines for Malaria Venture Category v t e Protozoan infection : SAR and Archaeplastida SAR Alveolate Apicomplexa Conoidasida / Coccidia Coccidia : Cryptosporidium hominis / Cryptosporidium parvum Cryptosporidiosis Cystoisospora belli Isosporiasis Cyclospora cayetanensis Cyclosporiasis Toxoplasma gondii Toxoplasmosis Aconoidasida Plasmodium falciparum / vivax / ovale / malariae / knowlesi Malaria Blackwater fever Babesia Babesiosis Ciliophora Balantidium coli Balantidiasis Heterokont Blastocystis Blastocystosis Pythium insidiosum Pythiosis Archaeplastida Algaemia : Prototheca wickerhamii Protothecosis
Ear Flare OMIM

'Near-head,' intermediate, and 'flare' types can be recognized. The data of Kloepfer (1946) suggested complex genetics. Inheritance - ?
Foot Fetishism Wikipedia

Fenichel, The Psychoanalytic Theory of Neurosis (1946) p. 327 ^ O. Fenichel, The Psychoanalytic Theory of Neurosis (1946) p. 343 ^ Georges Bataille, Visions of Excess (1985) p. 23 ^ AJ Giannini et al., op. cit. ^ Shaw, WJ (1979).
Burning Feet Syndrome Wikipedia

Indian Medical Gazette, Calcutta, 1946, 81: 22-26. Journal of the American Medical Association, Chicago, 1946, 131: 1177.
Malaria Wikipedia

The mosquitoes remain on the wall until they fall down dead on the floor. Insecticide treated nets [ edit ] A mosquito net in use. Mosquito nets help keep mosquitoes away from people and reduce infection rates and transmission of malaria. Nets are not a perfect barrier and are often treated with an insecticide designed to kill the mosquito before it has time to find a way past the net. Insecticide-treated nets are estimated to be twice as effective as untreated nets and offer greater than 70% protection compared with no net. [73] Between 2000 and 2008, the use of ITNs saved the lives of an estimated 250,000 infants in Sub-Saharan Africa. [74] About 13% of households in Sub-Saharan countries owned ITNs in 2007 [75] and 31% of African households were estimated to own at least one ITN in 2008. ... That number increased to 20.3 million (18.5%) African children using ITNs in 2007, leaving 89.6 million children unprotected [76] and to 68% African children using mosquito nets in 2015. [77] Most nets are impregnated with pyrethroids , a class of insecticides with low toxicity . ... According to the WHO and UNICEF, deaths attributable to malaria in 2015 were reduced by 60% [77] from a 2000 estimate of 985,000, largely due to the widespread use of insecticide-treated nets and artemisinin-based combination therapies. [74] In 2012, there were 207 million cases of malaria.

ICAM1, FCGR2B, HBB, CD36, NOS2, FCGR2A, TNF, CR1, G6PD, CRP, HP, ACKR1, GYPA, SLC4A1, GYPB, NCR3, TIRAP, GYPC, LTBR, CISH, IFNG, HMOX1, PKLR, ABO, ANK1, AQP4, ATP2B4, HBG2, CYTB, ENOSF1, MSMB, MST1, ZNF536, LINC00944, SMARCB1, DHODH, PDR, TREML4, ZNF804A, OR51F1, OR51B5, CDH13, PROCR, SPATA3, OR51N1P, DHFR, DDT, RECQL4, FAM155A, IGHG3, IL4, MMP26, IL6, IL10, TLR9, HLA-DRB1, CSMD1, HBE1, DNAJC5, TMPRSS13, KLHL3, HDGFL2, TLR4, ATAD1, LMLN, TENM3-AS1, MECP2, POMGNT2, MBL2, TFRC, TGFB1, MIF, HLA-B, HAMP, DHPS, SERPINA3, TLR2, IL1B, FOXP3, FHL5, ACOT7, POTEKP, POTEM, GEM, KIR3DL1, RN7SL263P, ACTG2, ACTG1, ACTB, ACTBL2, HBA2, CYP2B6, HSPA4, LSAMP, TRAP, FCGR3B, HSP90AA1, IL1A, LAMP3, CD81, OR10A4, CCL5, ABCB1, FAS, CD40LG, TEP1, CXCL8, IARS1, HLA-G, CTLA4, HBA1, INSRR, ANGPT2, TYMS, CFH, GSTP1, IFNAR1, AGT, GYPE, FCGR3A, TXN, IL13, HSPB3, APOE, MTCO2P12, ISYNA1, FCGR2C, FYB1, VDR, HLA-A, GSTM1, GSR, ATR, MBL3P, LAIR1, PNP, IL12B, MNAT1, IL1RN, CYP2D6, IGF1, CD55, ACHE, DECR1, COX2, IL3, CCL2, MAPK1, NLRP3, FBXW7, HAVCR2, THBD, VPS51, EMP1, ITGA2B, PTGS2, ANC, IL10RA, XPO1, VNN1, PLEK, UMPS, IL2, IL2RA, TPPP, VWF, ISG20, ADAMTS13, IRF1, IL7R, AIMP2, IL12RB1, CLEC11A, METAP2, CDK5R1, ING1, IL18R1, PGD, HAP1, H6PD, PRDX5, GRAP2, CXCL9, MMP9, MPO, TAP1, CCL4L2, COX1, EBI3, ITGAX, COX3, TLR6, CXCL11, MTHFR, NFKB2, NFYA, NOS1, TBC1D9, ORC1, MCF2, AKAP13, RNF19A, TLR7, NT5C3A, IRAK4, KIR2DS1, CCL4, KIR3DL2, ICOS, COQ2, PSIP1, PECAM1, TPT1, RNASE3, ARTN, TP53, POLDIP2, PDCD1, TLR1, AHSA1, UBL4A, AQP3, AGRP, H3C9P, CYP2C8, CYP2C19, GTF2H4, CRK, RNA18SN5, ANXA2, H3P37, CASP1, NANP, CCL4L1, MAPK14, CXCR3, GNAS, GLO1, FCN2, SMIM10L2B, FKBP4, CD27, FOXO3, RBM45, HM13, IL33, HK1, CCR5, IFNA13, IFNA1, H3P42, DNAJB1, CHIT1, CYP3A4, SMIM10L2A, EGF, CHI3L1, CAT, EPHA2, NSFL1C, ADRB2, MYMX, COX8A, GAPDH, ABCB6, NR1I3, TREML1, PUM3, FMN1, TICAM2, TRIM13, BMS1, FZD4, RABEPK, LANCL1, FUT9, TNFSF13B, DCTN6, CXCR6, ARL6IP5, MRGPRX1, ZNRD2, ASPM, KAT5, RAB7B, CIB1, SEMA3C, ARMH1, STING1, CFDP1, CPQ, MYLK4, DLC1, AKR1A1, PIEZO1, TMPRSS11D, HDAC9, CARTPT, DEFB4B, TIMELESS, SPHK1, TMED7-TICAM2, PSC, VNN2, PROM1, UPK3B, H3P23, H3P28, TNFRSF11A, TNFRSF18, TP63, PDXK, CNTNAP1, DHX16, STK24, H3P19, LOH19CR1, WASHC1, WASH6P, LPAR2, MIR146A, APOBEC3B, SPAG6, CLOCK, ATG5, MIR142, AIM2, ABCG2, PCSK9, MIR155, NCF1, PPIG, MIR29A, VN1R17P, GPR166P, CD163, MIR451A, CXADRP1, ARHGEF2, CERS1, SPINK5, MASP2, GEMIN4, ACD, TLR8, MPPE1, MCPH1, HSPA14, RNF34, TMED7, ARMC9, PPP1R2C, IL22, TRAF3IP2, A1CF, PDCD1LG2, SLC44A4, SGSM3, MCAT, HPGDS, B3GAT1, ROPN1L, PHGDH, RAB14, IL23A, ABCG4, IFIH1, CFC1, BTNL2, MARCHF1, POLE4, CMC2, TMED9, ACKR3, PDXP, RHOF, AICDA, POLD4, RBM25, TOLLIP, TREM1, LGR6, ADA2, BACH2, ERAP1, GOLPH3, PARS2, KRT88P, TRIM5, IL17RE, CHP1, GPR151, NRSN1, EIF5AL1, CD160, APCDD1, ERFE, OXER1, DNAJB1P1, DSTN, GPRC6A, CCNI, ADIRF, EBNA1BP2, TMED2, EHD1, RNPS1, HPSE, SEPTIN9, SCLT1, NT5C2, SLC25A21, LEO1, NLRP12, TIMD4, CDCA5, DBA2, CARD16, PTPMT1, CGAS, RAB39B, TADA1, MRGPRX3, MRGPRX4, PGLS, PANX1, SPO11, LPAR3, CBX5, POFUT2, SPPL3, NBEAL2, LUC7L, PTPRC, FGF23, EIF5, FLT3LG, FLT1, FECH, FBN2, FBN1, FANCD2, F3, EPO, ENO2, ADGRE1, ELK4, ELF4, EIF5A, EIF4G2, CXADR, EGR3, EDNRA, EDN1, S1PR3, RCAN1, ATN1, DNMT1, DEFB4A, DHX9, ACE, DBP, CYP1A2, CYC1, GABPA, GCHFR, GDF1, GPR42, IL4R, IL1R1, IGFBP1, IFNGR1, IFNB1, IFNA2, IFI27, IDE, HTN3, HSPA9, HSD11B1, HRES1, HPRT1, HPR, HPGD, HMGB1, HLA-DOA, UBE2K, HGF, SERPIND1, HBG1, GTF3A, GSTT1, GSN, GPX1, GPT, GRK5, CYBB, CTSL, IL9, ANXA1, C3, BSG, BRS3, BRCA2, PRDM1, BCL2, BAX, ASPA, ASIP, ARR3, NUDT2, ANXA7, ANXA4, ANPEP, CSH2, AMBP, ALOX5, ALB, AHR, AFP, ADSL, ADRA2B, ADRA1A, ADORA2A, ADH1B, ADA, ACP1, ACACA, CAST, CASR, CD1B, CD1C, CSH1, CSF1R, CSF1, CS, CRYZ, CREM, CR2, CLDN4, CPB1, CNTF, CCR4, CLU, ERCC8, CTSC, CEL, CDC25C, CD69, CD68, CD40, ENTPD1, CD34, CD28, CD19, CD14, CD9, CD1E, CD1D, IL5, IL12A, FOSL1, SELE, SPTA1, SPP1, SPINK1, SPG7, SOD3, SOD1, SMN1, SLC16A1, SLC11A1, SLC6A7, SLC2A1, SGCG, SET, SEA, ABCA1, SDC1, CXCL5, CCL22, CCL18, CCL3L1, CCL3, CCL1, SAFB, SORT1, RPS19, RBP2, RANBP2, PEX19, SSR2, SSTR4, DENND2B, STAT6, DDX39B, PRRC2A, PFBI, RAB7A, CXCR4, MOGS, ZBTB16, TRPV1, VCP, USP1, TYRP1, TTR, TTPA, TRPC1, TRP-AGG2-5, TPO, TPH1, TNFRSF1B, TLR3, TGFB2, TRBV20OR9-2, TCN2, HNF1A, TADA2A, ADAM17, TAC1, STK3, PTPRH, PTHLH, IL15, KIR3DS1, MAL, MAF, LTB, LTA, LMAN1, LEPR, LDLR, LCN2, LBR, RPSA, LAG3, KRT13, KNG1, KIR2DS5, PSMD9, KIR2DL3, KIR2DL2, KDR, KCNG1, KARS1, ITPA, ITGB2, ITGAM, ITGAL, CXCL10, IDO1, ILF3, IL18, MAP2, MAP6, MEFV, MVD, PSMD7, PSMD2, PSMB9, PSEN1, PSAP, PRSS1, PROC, MAP2K1, PRKG1, PRKAR1A, PPP1R1A, PPARG, SEPTIN4, PLP1, PGM1, PGAM1, P2RX7, SLC22A18, TNFRSF11B, OMD, ODC1, NOS3, NQO2, NFE2L2, NEK2, MYD88, MYC, H3P5
- Malaria, Susceptibility To OMIM
  
  A reduction in mortality greater than that attributable directly to malaria had been observed after the prevention of malaria by insecticides, chemoprophylaxis, and insecticide-impregnated bed nets. Previous observations that direct malaria mortality cannot account for observed hemoglobin S gene frequencies suggest that the findings of this study may apply equally to other malaria resistance genes. ... Although the relative strength of the protection is less than that of the sickle-cell variant, the greater frequency of the DQB1 (see HLA-DQB1; 604305) polymorphism makes the net effect on resistance to malaria comparable.
- Malaria Orphanet
  
  A life-threatening parasitic disease caused by Plasmodium ( P. ) parasites that are transmitted by Anophles mosquito bites to humans and is typically clinically characterized by attacks of fever, headache, chills and vomiting.
- Malaria GARD
  
  Malaria is a serious and sometimes fatal disease caused by a parasite that commonly infects a certain type of mosquito which feeds on humans. Infection with malaria parasites may result in a wide variety of symptoms, ranging from absent or very mild symptoms to severe disease and even death. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. In general, malaria is a curable disease if diagnosed and treated promptly and correctly. Treatment depends on many factors including disease severity, the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.
- Malaria Mayo Clinic
  
  To reduce malaria infections, world health programs distribute preventive drugs and insecticide-treated bed nets to protect people from mosquito bites. The World Health Organization has recommended a malaria vaccine for use in children who live in countries with high numbers of malaria cases. Protective clothing, bed nets and insecticides can protect you while traveling. ... Sprays containing permethrin are safe to apply to clothing. Sleep under a net. Bed nets, particularly those treated with insecticides, such as permethrin, help prevent mosquito bites while you are sleeping.