G1 and G2 neuroendocrine neoplasms are called neuroendocrine tumors (NETs) – formerly called carcinoid tumours. ... Unsourced material may be challenged and removed. ( November 2015 ) ( Learn how and when to remove this template message ) NETs from a particular anatomical origin often show similar behavior as a group, such as the foregut (which conceptually includes pancreas, and even thymus, airway and lung NETs), midgut and hindgut ; individual tumors within these sites can differ from these group benchmarks: Foregut NETs are argentaffin negative. ... Not all cells are immediately killed; cell death can go on for up to two years. [ citation needed ] PRRT was initially used for low grade NETs. It is also very useful in more aggressive NETs such as Grade 2 and 3 NETs [83] [84] provided they demonstrate high uptake on SSTR imaging to suggest benefit. ... AJCC Cancer Staging Manual (8 ed.). Springer . pp. 415–16. ISBN 978-3-319-40617-6 . ^ Kimura W, Kuroda A, Morioka Y (July 1991). ... Archived from the original on January 8, 2010. ^ a b Langley, K. (1994). "The Neuroendocrine Concept Today".

However in some cases, a pancreatic NET occurs outside of the pancreas. A NET arises from cells that produce hormones, so the tumor can also produce hormones. ... Pancreatic NETs are called either functional or nonfunctional. A functional pancreatic NET causes specific symptoms because it makes extra hormones, such as gastrin, insulin, or glucagon. ... Pancreatic NETs can be hard to diagnosis, often not identified until 5 to 10 years after they begin to grow. Most pancreatic NETs are not inherited and occur sporadically in people with no family history of NETs.

A neuroendocrine tumor (NET) is a rare type of tumor that arises from specialized body cells called neuroendocrine cells . ... Pancreatic neuroendocrine tumors (also called islet cell tumors) - NETs that typically arise in the pancreas, although they can occur outside the pancreas. A p heochromocytoma is another, rarer type of NET that usually develops in the adrenal gland , but can also arise in other parts of the body. ... Functional NETs produce a specific set of symptoms due to the production of excess hormones, while non-functional NETs generally do not cause specific symptoms. In many cases, a person has no symptoms until the tumor spreads to the liver and/or impairs the function of an organ or system. This can make NETs very hard to diagnose. The majority of NETs are not inherited and occur sporadically in people with no family history of NETs.

The mosquitoes remain on the wall until they fall down dead on the floor. Insecticide treated nets [ edit ] A mosquito net in use. Mosquito nets help keep mosquitoes away from people and reduce infection rates and transmission of malaria. Nets are not a perfect barrier and are often treated with an insecticide designed to kill the mosquito before it has time to find a way past the net. Insecticide-treated nets are estimated to be twice as effective as untreated nets and offer greater than 70% protection compared with no net. [73] Between 2000 and 2008, the use of ITNs saved the lives of an estimated 250,000 infants in Sub-Saharan Africa. [74] About 13% of households in Sub-Saharan countries owned ITNs in 2007 [75] and 31% of African households were estimated to own at least one ITN in 2008. ... That number increased to 20.3 million (18.5%) African children using ITNs in 2007, leaving 89.6 million children unprotected [76] and to 68% African children using mosquito nets in 2015. [77] Most nets are impregnated with pyrethroids , a class of insecticides with low toxicity . ... In April 1894, a Scottish physician, Sir Ronald Ross , visited Sir Patrick Manson at his house on Queen Anne Street, London.

Many Phlebotomine sandfly attacks occur at sunset rather than at night, so it may also be useful to put nets over doors and windows or to use insect repellents . ... Travel Medicine and Infectious Disease . 5 (3): 150–8. doi : 10.1016/j.tmaid.2006.09.004 . ... Caister Academic Press. ISBN 978-1-904455-28-8 . Archived from the original on 23 April 2008. [ page needed ] ^ Dacie JV, Bain BJ, Bates I (2006). ... The Cochrane Database of Systematic Reviews (8): CD008736. doi : 10.1002/14651858.CD008736.pub2 . ... Archived from the original on 10 December 2015 . Retrieved 8 December 2015 . ^ Birsel R (28 June 2002).

PanNETs are a type of neuroendocrine tumor , representing about one third of gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Many PanNETs are benign , while some are malignant . ... Contents 1 Types 2 Signs and symptoms 3 Diagnosis 4 Staging 5 Treatment 6 Genetics 7 References 8 External links Types [ edit ] The majority of PanNETs are benign , while some are malignant . ... However, morphological imaging alone is not sufficient for a definite diagnosis [14] [16] On biopsy , immunohistochemistry is generally positive for chromogranin and synaptophysin . [17] Genetic testing thereof typically shows altered MEN1 and DAXX / ATRX . [17] Staging [ edit ] The 2010 WHO classification of tumors of the digestive system grades all the neuroendocrine tumors into three categories, based on their degree of cellular differentiation (from well-differentiated "NET G1" through to poorly-differentiated "NET G3"). ... However, there are some specific differences, which are discussed here. [8] In functioning PanNETs, octreotide is usually recommended prior to biopsy [8] : 21 or surgery [8] : 45 but is generally avoided in insulinomas to avoid profound hypoglycemia . [8] : 69 PanNETs in Multiple endocrine neoplasia type 1 are often multiple, and thus require different treatment and surveillance strategies. [8] Some PanNETs are more responsive to chemotherapy than are gastroenteric carcinoid tumors. ... The ASCO Post. May 15, 2011, Volume 2, Issue 8 "Archived copy" . Archived from the original on 2013-01-17 .

A rare, genetic, primary orthostatic disorder characterized by dizziness, palpitations, fatigue, blurred vision and tachycardia following postural change from a supine to an upright position, in the absence of hypotension. A syncope with transient cognitive impairment and dyspnea may also occur. The norepinephrine transporter deficiency leads to abnormal uptake and high plasma concentrations of norepinephrine.

A group of esophageal epithelial neoplasms characterized by neuroendocrine differentiation, comprising well-differentiated neuroendocrine tumors (NETs), poorly differentiated neuroendocrine carcinomas (NECs), and mixed neuroendocrine-non-neuroendocrine neoplasms, an umbrella category including mixed adenoneuroendocrine carcinoma. ... NECs may also arise in other parts of the esophagus. On endoscopy, NETs usually appear as small polypoid or nodular submucosal masses, while NECs are large, infiltrative, and ulcerated. Patients most commonly present with dysphagia, pain, weight loss, and sometimes melena. Metastatic NETs may be associated with carcinoid syndrome.

Alani et al. (1994) reported a British family from Blackburn with a previous diagnosis of spherocytosis (SPH; see 182900) in which the proband, 2 of his sibs, and his son exhibited temperature-sensitive pseudohyperkalemia. ... Studies of the temperature dependence of passive permeability showed that the minimum in the passive permeability, which was seen in normal cells at 8-10 degrees centigrade, was shifted up to 23 degrees centigrade in these abnormal cells, such that the permeability at 0 degrees centigrade exceeded that at 37 degrees centigrade. ... Further investigation revealed a red cell potassium leak that was 8-fold higher than control and a 2- to 3-fold increase in activity of the sodium/potassium pump, resulting in a diagnosis of cryohydrocytosis. ... Molecular Genetics Bruce et al. (2005) studied 11 pedigrees with dominantly inherited hemolytic anemias, 3 spherocytic (see SPH4, 612653) and 8 stomatocytic, including families previously reported by Coles et al. (1999, 1999), Haines et al. (2001), and Gore et al. (2004). ... Unidirectional K(+) influx measurements showed that the patient's cells had abnormally high activities of the K(+)Na(+)/H(+) exchanger (KNHE) and the K(+),Cl(-) cotransporter (KCC), which could account for the observed net movements of cations. Neither chloride nor cation conductance in patient RBCs differed from that of healthy donors.

Of 650 arrested in New York City, the government managed to deport just 43. [12] When Palmer replied to the Senate's questions of October 17, he reported that his department had amassed 60,000 names with great effort. ... Chapin on the South Bend News-Times – November 8, 1919 As Attorney General Palmer struggled with exhaustion and devoted all his energies to the United Mine Workers coal strike in November and December 1919 , [14] Hoover organized the next raids. ... Palmer replied that he could not use individual arrests to treat an "epidemic" and asserted his own fidelity to constitutional principles. ... Then, in testimony before the House Rules Committee on May 7–8, Post proved "a convincing speaker with a caustic tongue" [23] and defended himself so successfully that Congressman Edward W. ... ISBN 978-1-84989-944-4 . ^ a b c d e f Avrich, Paul, Sacco and Vanzetti: The Anarchist Background , Princeton University Press, ISBN 0-691-02604-1 (1991), pp. 140–143, 147, 149–156 ^ "Plotter Here Hid Trail Skillfully; His Victim Was A Night Watchman", The New York Times, 4 June 1919 ^ "Wreck Judge Nott's Home", The New York Times, 3 June 1919 ^ Hagedorn, 229–30; Coben, 211 ^ Pietruszka, 146–7 ^ Coben 217–8 ^ Coben, 207–9 ^ Coben, 214–5 ^ Coben, 219–21; Post, 28–35.

The disease was first linked to malaria by the Sierra Leonean physician Dr John Farrell Easmon in his 1884 pamphlet entitled The Nature and Treatment of Blackwater Fever. ... Prominent victims [ edit ] Prior to his photography career, Henri Cartier-Bresson [6] contracted blackwater fever while hunting in Western Africa. Expecting to die, he sent instructions to his family on his wishes for a funeral. ... He was misdiagnosed four times and required airlift to Uganda, where he narrowly recovered from severe symptoms. [8] Aeneas, Jeannie Gunn 's husband, is described as having died from Blackwater Fever or Malarial Dysentry at Elsey Station in the Northern Territory in 1903. [ citation needed ] She later authored the classic account We of the Never Never . ... Clinical Infectious Diseases . 32 (8): 1133–1140. doi : 10.1086/319743 .

The kidney plays a key role in this homeostasis under normal circumstances, owing to its ability to vary bicarbonate reclamation and net acid excretion over a wide range. ... Seedat (1964) reported a family with 8 affected members in 4 generations. ... In another first-cousin marriage, 4 of his half sibs were affected. Kuhlencordt et al. (1967) observed affected monozygotic twins whose parents were first cousins. ... Molecular Genetics Karet et al. (1998) analyzed the SLC4A1 gene (109270) in 17 families with autosomal recessive distal RTA but found no mutations. In 8 of 9 renal tubular acidosis kindreds with normal audiometry linked to the ATP6N1B locus, Smith et al. (2000) identified homozygous mutations in the ATP6N1B gene (ATP6V0A4; 605239).

One prominent such usage was by Roger Scruton in his 2004 book England and the Need for Nations . Contents 1 In psychiatry 2 Southey's usage 3 Political usage 4 See also 5 References In psychiatry [ edit ] In psychiatric usage, oikophobia may narrowly refer to fear of the physical space of the home interior, where it is especially linked to the fear of household appliances , baths , electrical equipment , and other aspects of the home perceived to be potentially dangerous. [2] In this psychiatric context, the term is properly applied to fear of the objects within the house , whereas the fear of the house itself is referred to as domatophobia . [2] In the post-World War II era, some commentators used the term to refer to a supposed "fear and loathing of housework " experienced by women who worked outside of the home and who were attracted to a consumerist lifestyle . [4] Southey's usage [ edit ] In his Letters from England (1808), Robert Southey describes oikophobia as a product of "a certain state of civilisation or luxury." referring to the habit among wealthy people to visit spa towns and seaside resorts in the summer months. He also mentions the fashion for picturesque travel to wild landscapes, such as the highlands of Scotland . [5] Southey's link of oikophobia to wealth and the search for new experiences was taken up by other writers, and cited in dictionaries . [6] A writer in 1829 published an essay about his experience witnessing the aftermath of the Battle of Waterloo , saying: [7] [T]he love of locomotion is so natural to an Englishman that nothing can chain him home, but the absolute impossibility of living abroad. ... In 1959, Anglo-Egyptian author Bothaina Abd el-Hamid Mohamed used Southey's concept in his book Oikophobia: or, A literary craze for education through travel . [8] Political usage [ edit ] Part of a series on Discrimination General forms Age Class ( Caste ) Physical Disability Education Economic Employment Genetics Hair texture Height Housing Language Looks Race / Ethnicity / Nationality Rank Religion Sanity Sex Sexual orientation Size Skin color Specific forms Social Acephobia Adultism Amatonormativity Anti-albinism Anti-autism Anti-homelessness Anti-intellectualism Anti-intersex Anti-left handedness Anti-Masonry Antisemitism (Judeophobia) Aporophobia Audism Biphobia Clannism Cronyism Drug use Elitism Ephebiphobia Fatism Gerontophobia Heteronormativity Heterosexism HIV/AIDS stigma Homophobia Leprosy stigma Lesbophobia Misandry Misogyny Nepotism Pedophobia Perpetual foreigner Pregnancy Reverse Sectarianism Supremacism Black White Transphobia Non-binary Transmisogyny Vegaphobia Xenophobia Religious Ahmadiyya Atheism Baháʼí Faith Buddhism Catholicism Christianity post–Cold War era Druze Falun Gong Hinduism Persecution Islam Persecution Jehovah's Witnesses Judaism Persecution LDS or Mormon Neopaganism Eastern Orthodox Oriental Orthodox Copts Protestantism Rastafarianism Shi'ism Sufism Sunnism Zoroastrianism Ethnic/national African Albanian American Arab Armenian Australian Austrian Azerbaijani British Canadian Catalan Chechen Chilean Chinese Croat Dutch English Estonian European Filipino Finnish French Georgian German Greek Haitian Hazara Hispanic Hungarian Igbo Indian Indonesian Iranian Irish Israeli Italian Japanese Jewish Khmer Korean Kurdish Malay Manchu Mexican Middle Eastern Mongolian Montenegrin Pakistani Pashtun Polish Portuguese Quebec Romani Romanian Russian Scottish Serb Slavic Somali Soviet Tatar Thai Tibetan Turkish Ukrainian Venezuelan Vietnamese Western Manifestations Blood libel Bullying Compulsory sterilization Counter-jihad Cultural genocide Defamation Democide Disability hate crime Dog-whistle politics Eliminationism Ethnic cleansing Ethnic conflict Ethnic hatred Ethnic joke Ethnocide Forced conversion Freak show Gay bashing Gendercide Genital modification and mutilation Genocide examples Glass ceiling Hate crime Hate group Hate speech online Homeless dumping Indian rolling Lavender scare LGBT hate crimes Lynching Mortgage Murder music Occupational segregation Persecution Pogrom Purge Red Scare Religious persecution Religious terrorism Religious violence Religious war Scapegoating Segregation academy Sex-selective abortion Slavery Slut-shaming Trans bashing Victimisation Violence against women White flight White power music Wife selling Witch-hunt Policies Age of candidacy Blood purity Blood quantum Crime of apartheid Disabilities Catholic Jewish Ethnocracy Ethnopluralism Gender pay gap Gender roles Gerontocracy Gerrymandering Ghetto benches Internment Jewish quota Jim Crow laws Law for Protection of the Nation McCarthyism MSM blood donation restrictions Nonpersons Numerus clausus (as religious or racial quota) Nuremberg Laws One-drop rule Racial quota Racial steering Redlining Same-sex marriage (laws and issues prohibiting) Segregation age racial religious sexual Sodomy law State atheism State religion Ugly law Voter suppression Countermeasures Affirmative action Anti-discrimination law Cultural assimilation Cultural pluralism Diversity training Empowerment Feminism Fighting Discrimination Hate speech laws by country Human rights Intersex rights LGBT rights Masculism Multiculturalism Nonviolence Racial integration Reappropriation Self-determination Social integration Toleration Related topics Allophilia Anti-cultural, anti-national, and anti-ethnic terms Bias Christian privilege Civil liberties Cultural assimilation Dehumanization Diversity Ethnic penalty Eugenics Internalized oppression Intersectionality Male privilege Masculism Medical model of disability autism Multiculturalism Net bias Neurodiversity Oikophobia Oppression Police brutality Political correctness Polyculturalism Power distance Prejudice Prisoner abuse Racial bias in criminal news Racism by country Religious intolerance Second-generation gender bias Snobbery Social exclusion Social model of disability Social stigma Stereotype threat The talk White privilege v t e In his 2004 book England and the Need for Nations , British conservative philosopher Roger Scruton adapted the word to mean "the repudiation of inheritance and home." [9] He argues that it is "a stage through which the adolescent mind normally passes," [10] but that it is a feature of some, typically leftist , political impulses and ideologies that espouse xenophilia , i.e. preference for foreign cultures. [11] Scruton uses the term as the antithesis of xenophobia . [12] In his book, Roger Scruton: Philosopher on Dover Beach , Mark Dooley describes oikophobia as centered within the Western academic establishment on "both the common culture of the West , and the old educational curriculum that sought to transmit its humane values." ... In August 2010, James Taranto wrote a column in the Wall Street Journal entitled "Oikophobia: Why the liberal elite finds Americans revolting", in which he criticizes supporters of the proposed Islamic center in New York as oikophobes who were defending Muslims and aimed to "exploit the 9/11 atrocity ." [14] In the Netherlands , the term oikophobia has been adopted by politician and writer Thierry Baudet , which he describes in his book, Oikophobia: The Fear of Home .

A rare neoplastic disease characterized by occurrence of atypical and aggressive gastric type 1 neuroendocrine tumors (NET) in early adulthood. The tumors often show nodal infiltration requiring total gastrectomy. ... Patients present high serum gastrin concentrations and iron-deficiency anemia (rather than megaloblastic anemia, which is a typical feature in patients with sporadic gastric type 1 NET, where the tumor usually arises on the background of autoimmune atrophic gastritis).

In Dogger Bank itch, sensitivity is acquired after repeated handling of the sea chervils that become entangled in fishing nets. [ citation needed ] The specific toxin responsible for the rash was determined to be the sulfur -bearing salt (2-hydroxyethyl) dimethylsulfoxonium chloride. [3] This salt is also found in some sea sponges and has potent in vitro activity against leukemia cells. [4] Treatment [ edit ] A study of two cases in 2001 suggests that the rash responds to oral ciclosporin . ... The sea chervil, abundant in the area, frequently came up with the fishing nets and had to be thrown back into the water. ... Although the rash disappeared after leaving the area, it reappeared with greater severity when he returned to the area and performed the same activities; this time the rash spread to his neck and face, and continued to ooze serum for two months. [7] See also [ edit ] Seaweed dermatitis References [ edit ] ^ James, William D.; Berger, Timothy G.; et al. (2006).

Aznar et al. (1984) reported a man with a history of excessive bleeding after minor trauma and dental extractions. The patient, 3 of his children, and 1 grandchild showed in vitro increased red cell fallout from the blood clot and increased tissue plasminogen activator activity. ... Defective release of tPA antigen was found in 8 of the 91 patients. A partial family study of 6 of the 8 patients included 10 family members with and 21 without DVT. ... Molecular Genetics Among 51 healthy males, Jern et al. (1999) found that a 311-bp Alu insertion/deletion (I/D) polymorphism in intron 8 of the PLAT gene was significantly associated with the vascular release rate of tPA as assessed by a forearm venous occlusion test. Individuals homozygous for the insertion had significantly increased net local release rates than those who were either heterozygous or homozygous for the deletion. ... Ladenvall et al. (2003) screened 240 Swedish individuals without cardiovascular disease for 8 SNPs and an Alu insertion polymorphism at the PLAT locus, as well as for a polymorphism (173360.0002) in PAI1 promoter.

Depending on the mosquito vector, and the affected community, a variety of prevention methods may be deployed at one time. Insecticidal nets and indoor residual spraying [ edit ] The use of insecticide treated mosquito nets (ITNs) are at the forefront of preventing mosquito bites that cause malaria. ... "The Impact of Pyrethroid Resistance on the Efficacy of Insecticide-Treated Bed Nets against African Anopheline Mosquitoes: Systematic Review and Meta-Analysis" . ... "Trends of Dengue Disease Epidemiology" . Virology:Research and Treatment . 8 : 1178122X17695836. doi : 10.1177/1178122X17695836 . ... "Zika Virus: Transmission, Detection, Control, and Prevention" . Front Microbiol . 8 : 110. doi : 10.3389/fmicb.2017.00110 . ... PLOS Neglected Tropical Diseases . 8 (9): e3115. doi : 10.1371/journal.pntd.0003115 .

] and the use of large-bore tubes inserted into the esophagus to forcefully lavage it. [17] [ unreliable medical source? ] Endoscopic [ edit ] The Roth net can be inserted through the endoscope to remove pieces of the obstructed food. ... Traditional endoscopic techniques involved the use of an overtube, a plastic tube inserted into the esophagus prior to the removal of the food bolus, in order to reduce the risk of aspiration into the lungs at the time of endoscopy. [7] However, the "push technique", which involves insufflating air into the esophagus, and gently pushing the bolus toward the stomach instead, has emerged as a common and safe way of removing the obstruction. [7] [18] Other tools may be used to remove food boluses. The Roth Net is a mesh net that can be inserted through the endoscope, and opened and closed from the outside; it can be used to retrieve pieces of obstructed food. ... Primary and definitive diagnosis and therapy". Surgical Endoscopy . 3 (4): 195–8. doi : 10.1007/BF02171545 . PMID 2623551 . ^ a b Peksa, GD; DeMott, JM; Slocum, GW; Burkins, J; Gottlieb, M (April 2019). ... Gastrointestinal Endoscopy . 53 (2): 193–8. doi : 10.1067/mge.2001.112709 . PMID 11174291 . ^ a b c d Kerlin P, Jones D, Remedios M, Campbell C (2007). ... Can. J. Gastroenterol . 22 (10): 805–8. doi : 10.1155/2008/682082 . PMC 2661297 .

Contents 1 Senses during flight 2 Effects of disorientation 3 Spatial orientation 3.1 The otolith organs and orientation 4 Non-visible horizon 5 In the media 6 Examples 7 See also 8 References 9 External links Senses during flight [ edit ] There are four physiologic systems that interact to allow humans to orient themselves in space. ... Because of inertial forces created by acceleration of the aircraft along with centrifugal force caused by turning, the net gravitoinertial force sensed primarily by the otolith organs is not aligned with gravity, leading to perceptual misjudgment of the vertical. ... The 20th pilot also lost control of his aircraft, but in another maneuver. ... A powerful tumbling sensation ( vertigo ) can be set up if the pilot moves his or her head too much during instrument flight. ... ] that singer Jim Reeves was suffering from spatial disorientation when his Beechcraft aircraft crashed in the Brentwood area of Nashville, Tennessee, during a violent thunderstorm on 31 July 1964, claiming the lives of both Reeves and his pianist Dean Manuel.

Avoid and exclude mosquitoes Limit exposure to mosquitoes by: Repairing any tears in the screens on windows, doors and camping gear Using mosquito netting over strollers and cribs Using mosquito netting when sleeping outdoors Selecting self-care products that don't have scents Use insect repellent Use insect repellent when mosquitoes are active. ... If you're using a spray repellent, apply it outdoors and away from food. You may need to reapply it 6 to 8 hours later if you're still in an area where mosquitoes are active. ... Some sporting goods stores sell clothing pretreated with permethrin. Don't wash bed nets or set them in sunlight, as this breaks down permethrin.