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    Serum creatinine alone may overestimate glomerular filtration rate and recent guidelines advocate the use of predictive equations such as the Modification of Diet in Renal Disease (MDRD) formula to estimate glomerular filtration rate (eGFR). [27] eGFR can also provide a baseline measurement of kidney function that can be used to monitor for side effects of certain anti-hypertensive drugs on kidney function. Additionally, testing of urine samples for protein is used as a secondary indicator of kidney disease. ... However, a Cochrane review that included 13 trials found that the effects of beta-blockers are inferior to that of other antihypertensive medications in preventing cardiovascular disease. [134] Resistant hypertension [ edit ] Resistant hypertension is defined as high blood pressure that remains above a target level, in spite of being prescribed three or more antihypertensive drugs simultaneously with different mechanisms of action . [135] Failing to take prescribed medications as directed is an important cause of resistant hypertension. [136] Resistant hypertension may also result from chronically high activity of the autonomic nervous system , an effect known as "neurogenic hypertension". [137] Electrical therapies that stimulate the baroreflex are being studied as an option for lowering blood pressure in people in this situation. [138] Refractory hypertension [ edit ] Main article: Refractory Hypertension Refractory hypertension is characterized by uncontrolled elevated blood pressure unmitigated by five or more antihypertensive agents of different classes, including a long-acting thiazide-like diuretic , a calcium channel blocker , and a blocker of the renin-angiotensin system . [139] People with refractory hypertension typically have increased sympathetic nervous system activity, and are at high risk for more severe cardiovascular diseases and all-cause mortality. [139] [140] Epidemiology [ edit ] Rates of hypertension in adult men in 2014. [141] Disability-adjusted life year for hypertensive heart disease per 100,000 inhabitants in 2004. [142] no data <110 110-220 220-330 330-440 440-550 550-660 660-770 770-880 880-990 990-1100 1100–1600 >1600 Adults [ edit ] As of 2014 [update] , approximately one billion adults or ~22% of the population of the world have hypertension. [143] It is slightly more frequent in men, [143] in those of low socioeconomic status , [6] and it becomes more common with age. [6] It is common in high, medium, and low income countries. [143] [144] In 2004 rates of high blood pressure were highest in Africa, (30% for both sexes) and lowest in the Americas (18% for both sexes). ... In the 19th and 20th centuries, before effective pharmacological treatment for hypertension became possible, three treatment modalities were used, all with numerous side-effects: strict sodium restriction (for example the rice diet [158] ), sympathectomy (surgical ablation of parts of the sympathetic nervous system ), and pyrogen therapy (injection of substances that caused a fever, indirectly reducing blood pressure). [158] [164] The first chemical for hypertension, sodium thiocyanate , was used in 1900 but had many side effects and was unpopular. [158] Several other agents were developed after the Second World War , the most popular and reasonably effective of which were tetramethylammonium chloride , hexamethonium , hydralazine , and reserpine (derived from the medicinal plant Rauvolfia serpentina ). ... However, more studies are needed to assess the optimal dose and the possible side effects. [174] Other animals [ edit ] Cats [ edit ] Hypertension in cats is indicated with a systolic blood pressure greater than 150 mm Hg, with amlodipine the usual first-line treatment. [175] Dogs [ edit ] Normal blood pressure can differ substantially between breeds but hypertension in dogs is often diagnosed if systolic blood pressure is above 160 mm Hg particularly if this is associated with target organ damage. [176] Inhibitors of the renin-angiotensin system and calcium channel blockers are often used to treat hypertension in dogs, although other drugs may be indicated for specific conditions causing high blood pressure. [176] References [ edit ] ^ a b c d e "High Blood Pressure Fact Sheet" .
    PPARG, APOA1, HSD11B2, MMP2, NOS3, ATP2B1, APOE, NR3C1, ECE1, GJA1, HIF1A, IL1B, CAV1, CAT, CYBA, AVP, NOX4, NOS2, CCL2, AGT, NPPB, ADRB1, REN, RGS2, AGTR2, KLK1, NPPA, NPR1, TNF, ADD1, CD36, MMP9, CRP, ACE, ACE2, TGFB1, LEP, IGF1, CYBB, EDNRA, PTGS2, EDN1, HMOX1, SERPINE1, AGTR1, UCP2, VWF, TH, UTS2, INS, HP, BDKRB2, PPARA, SOD1, GLP1R, ATP1A1, RGS5, AR, KCNMB1, SOD3, SOD2, SLC12A2, TRH, AQP1, GRK2, GJA5, TIMP1, OLR1, MTOR, VCAM1, BCL2, GPX1, ADRA2A, RELA, JUN, GSK3B, FOS, GAL, PRKCD, ADCY5, IKBKB, WNK1, WNK4, OXT, ATP1A2, ELN, HRH3, SCNN1B, SCNN1G, UMOD, ANXA1, SLC9A3R2, SCNN1A, TP53, GNAS, GUCY1A1, GCH1, CBS, FN1, COL3A1, PTH, POMC, COL1A1, GSTT1, TLR4, EPO, GNB3, CALCA, LPL, NEDD4L, SLC12A3, F12, VDR, CYP1A1, CYP11B1, ADIPOQ, KNG1, IL6, ALB, LEPR, STK39, GCG, ENG, HSD11B1, PLAT, ICAM1, FBN1, LOX, SELP, DRD2, SLC6A2, CCN2, AHR, EGFR, PLG, THBD, NCF1, C3, PRKG1, OXSR1, SH2B3, CXCR2, INPPL1, TRPC3, ERAP1, CMA1, ORAI1, PTPN1, CACNA1C, CLCNKA, GJA4, TGM2, CETP, AOC3, ALOX15, SLC6A18, STIM1, GCLC, TACR1, GSTP1, CRHR2, HTR2B, ALAD, VAV3, PTEN, DUSP5, KCNJ1, F11, IER3, MYO6, TRPC5, STK11, AOC1, UCN, ATP2B3, PROC, RPS6KB1, ITM2B, CELA2A, CHGA, CACNA2D1, NPTN, RALBP1, PPBP, GSTM1, NPY, ADRB2, ADRA2B, ADRA1A, GJC1, GSTT2, ADM, EDN3, CXCL2, ESR2, ATP6AP2, SLC9A3, MME, MYH7, MDH1, GNRH1, TPM1, APLN, FXYD2, LGALS3, ABCC1, CYP4A11, MYD88, GSTA5, ATOX1, REG3G, KL, LHB, MC2R, SLC5A2, NFE2L2, LTF, IL10, GP1BA, KDR, AGER, XDH, F3, MAS1, EDNRB, ARG1, CYP19A1, PNMT, NOS1, SLC8A1, CLOCK, AKT1, GSTM2, ACSM3, COMT, CHI3L1, IL1RN, DBH, MFN2, F11R, UTS2R, KCNQ1, APP, ADD2, AVPR1A, EPHX2, KCNA5, MMP7, CCR5, FADS1, HAVCR1, CDKN2A, SST, HDAC6, RAG1, SLC2A1, ALOX5, ADA, AQP2, FGF2, BDKRB1, ARG2, ARID1B, HSPD1, BECN1, EGLN1, NQO1, CRHR1, CNR1, ADAMTS16, BAX, MIF, CASP3, PDGFRB, AKT2, GNAI2, MAPK8, HTR1B, PRKCA, PTK2B, SRF, KYNU, CPS1, GRK5, AGTRAP, SLC6A3, CCL28, KCNJ11, TAC3, YWHAZ, HDAC8, SLC4A4, HSD3B1, TRHR, STS, UCP3, LRP2, CYP11A1, RHOA, NCF2, CTSC, ALOX12, NPY1R, SLC6A19, PLCD1, PRKCB, POSTN, CYP4F12, PDGFRA, IGF1R, RAMP2, F2R, SLC9A3R1, S1PR1, ABCC9, OPA1, IGFBP2, NISCH, NGF, LIPG, F7, KCNJ8, CLDN16, ENO1, ITGAV, KCNAB1, ATG7, CYP11B2, CYP17A1, ABAT, CORIN, AQP4, MTPN, HSPG2, CUL3, APOB, DUSP1, RFFL, DRD3, ACTC1, DYNLL1, TJP2, HSD17B4, CYP4A22, CD82, SQSTM1, FADD, GRK3, ADD3, GABBR1, ADORA1, RESP18, BAD, GNAI3, TNFRSF11B, ARHGDIA, H2AX, SLC2A3, NFKBIA, NGFR, KLHL3, RNPEP, RGS4, MAP1LC3A, CASP8, CASP9, RAD51, ATF2, OXTR, QDPR, PTPRJ, CCNE1, PTK2, PDGFB, ENTPD2, SERPINE2, PIK3R1, PKD1, PRKCE, MYOD1, COX5B, NR3C2, TACR3, FAH, ARRB2, HSD3B2, EP300, MC4R, ATP2A3, ATP5F1A, AVPR2, CDO1, NR2F2, TBXAS1, EIF4G2, MSX2, NUDT1, MYH9, SRC, COX2, BMPR2, BRCA1, KCNK3, LDLR, KCNJ5, ENPEP, PKD2, NOTCH3, FLT1, ACVRL1, PDE3A, FGF5, HFE, CACNB2, CFH, COX1, TGFBR2, JAK2, TRPC6, CDKN2B-AS1, ABCB6, ABCC6, CASZ1, STOX1, ENPP1, CACNA1H, PCSK9, ARHGAP42, LMNA, SMAD3, NT5C2, CFHR3, CCND1, SERPINA6, LYZ, CTLA4, ARMC5, PKHD1, FMR1, TET2, NOTCH1, NF1, MYH11, ANTXR2, B2M, FOXF1, MGP, TGFBR1, ALMS1, VHL, WT1, FMO3, CNNM2, ULK4, MKKS, GLA, PGPEP1, TGFBR3, RBM47, PLCE1, NFU1, TNFRSF11A, NOD2, TGFB3, TBX2, KRT8, SMAD6, CD46, MEF2A, HMBS, MOV10, L3MBTL4, ND1, MTTP, CFHR1, MYLK, ANGPTL6, FURIN, PLIN1, PMM2, PRKACA, PRTN3, ABCG8, IFIH1, GATA5, ATXN2, GRK6, RPTOR, H19, CD2AP, FGA, CYP21A2, CACNA1D, ACAT1, NKX2-5, CLCN2, ACTN4, COL4A1, CALR, BRCA2, CPOX, SRGAP3, OFD1, SESN2, MIR21, LRIG2, OR5B12, PDE11A, FGD4, BORCS7, TTC8, ADRB3, SLC25A11, DNAAF1, GPR101, ZNF831, ITGA8, PLEKHG1, ELP1, DBP, AGAP1, COL4A3, ZNF536, PAM16, BNC2, PDE8B, CRIP3, RAPGEF5, LRRC10B, PSTK, DECR1, APOL1, EML6, VANGL1, BMS1, CYP4F2, ARL6, BBS5, DIS3L2, PDE5A, MACROD2, STN1, EDA, PIK3CG, SMARCAL1, ERCC8, TRIM28, ND5, COQ7, SUGCT, MICALL2, XRCC4, ZMPSTE24, CFI, IDUA, DARS2, BBS10, ABCB1, PGF, LINC02875, SLC2A10, TMEM212, MKS1, INSR, MAFB, DPEP1, PLEKHH2, FAM131A, MFAP5, CEP290, IL17A, FGF23, TMEM70, BAG6, DPP4, FUZ, SGCZ, KRT18, WDPCP, COL4A4, COL4A5, TRNQ, TRNS1, TRNS2, SLC33A1, DNAJB11, TRNV, TRNW, MUC1, TAF1C, SELENBP1, P4HA2, TRIP13, SLC52A3, ALDH2, PHF21A, PGR-AS1, MYO9B, DYRK1B, ADA2, BBIP1, TMEM67, ND6, MTHFR, CYTB, COX3, TRNE, AIP, TRNC, TRNF, MMP14, TRNH, CST3, USP8, CERS5, TRNK, MPL, TRNL1, CEP19, BORCS7-ASMT, NLRP3, COL5A1, LPA, LZTFL1, LMX1B, CYP2J2, COL5A2, CYP3A4, NOTCH2, HOTTIP, ANGPT2, CYP3A5, MLXIPL, KLK4, NPHP1, TUBB6, IQCB1, PRRX1, BANF1, LRP6, NDUFS3, SMAD4, MAT2A, TARID, APLNR, ZDHHC2, KLHL29, NFATC2, NFIX, CYP2B6, PTPMT1, ADAMTSL4, CYP2C19, LYN, ANGPT1, APBB1IP, CCHCR1, LSP1, WRN, YES1, WNT2B, ERCC4, MTCO2P12, BBS2, GRK4, GPR39, CDH23, BBS4, GPR20, PTPN22, SWAP70, KIF1B, IFT172, ALX4, CAD, HPSE2, NSMCE2, HOXA-AS2, TRAF3IP1, GPT, TRIM32, SLC39A8, POU6F2, REST, ACACA, CAPZA1, ERCC6, BSCL2, TGFB2, ESR1, ABCG5, EIF4BP8, BBS1, CEP164, PON1, RNU1-4, EXT2, F2, FGF21, GML, LDLRAP1, EDA2R, LRRC7, G6PC, ZNF318, FRMD3, SLC12A1, BST1, KCTD1, ZFAT, COPD, SLC37A4, CC2D2A, NPHP4, WDR35, LEMD3, FOXE3, ARHGAP31, HECTD4, LINC00862, RGL3, GPC3, GH1, TRPV4, FES, VPS51, CFB, CUX2, RPGRIP1L, STK3, SGK1, FGFR2, LARS2, SHBG, RETN, SIRT1, SLC12A9, GBA, WDR19, NPHP3, HSPB8, ND4, HOXA3, BBS9, HLA-DPA1, HLA-DPB1, SLC22A7, CCDC28B, SDCCAG8, TM7SF2, HMGCS2, CDH18, PRKAR1A, ACTA2, PTPN11, C8orf37, TNXB, BBS12, TMEM237, PTGIS, HOXB7, HOXA11, FGD5, ATM, YY1AP1, TLR1, HBB, THPO, OSGEP, BBS7, IKZF5, INF2, POR, IFT27, RARRES2, INVS, POU3F4, AFG3L2, HGD, SLC52A2, VEGFA, ACTB, PPARGC1A, CLDN19, SPP1, FTO, CSK, CTNNB1, NOX1, HCRT, LCN2, HGF, GDF15, GSTK1, RNLS, DDAH1, CYP2C9, GABPA, PTX3, CSF2, F5, SLCO6A1, PIK3CD, GPR42, CABIN1, MAT2B, HSPA4, LPAR2, MMP3, PIK3CB, ACKR3, ANO1, CASR, PIK3CA, IL1A, RAC1, BEST1, HMGB1, NPR3, BDNF, BRS3, CLCNKB, THBS1, CXCR6, TXNRD3, MAPK3, LAMC2, EPAS1, SGSM3, SIRT3, PPIG, FAAH, IFNG, SSTR4, ARTN, TLR2, TRPV1, CD34, MOK, PITX2, ROS1, APRT, APOC3, BMP4, STAT3, SLC26A4, KLK3, PTGS1, ADAM17, PDC, SPHK1, MIR155, OR10A4, IRS1, SETD2, ROCK2, GPER1, MFAP1, AGRP, HPGDS, OSR1, IL18, DRD1, COL18A1, TNFRSF1B, ACR, MAPK1, CD59, CHDH, STK24, CYP2D6, ANPEP, ARSA, PPIA, MIR214, MIR29B1, APOA5, CHST3, MIR29A, P2RX7, DYM, ADORA2B, MIR204, IL4, CXCL8, ADRA1D, EGF, MIR145, MLC1, CRH, EMILIN1, RBP4, MTRR, SELPLG, TAC1, CYP1B1, CYP1A2, HDLBP, SELE, DUOX2, FAS, LOC102724197, PER1, ADM2, CX3CL1, MIR223, SLBP, SLC6A4, GCK, BTBD8, IGF2, SLC7A1, G6PD, GPR151, PPARGC1B, PLA2G7, MRGPRX1, LPAR3, SERPINA5, DAPK2, CCR2, KLF15, STAM2, MIR29B2, HLA-B, FLNA, CAST, ATP5PF, OXER1, OGA, AZU1, HEBP1, EIF2AK4, VN1R17P, S100A6, PRKAA2, RAMP1, S100A12, TRPM8, CRY2, TOR2A, PHACTR1, GPR166P, SCN10A, HTR2A, LGR6, GPRC6A, TLR3, PRKD1, ND2, FZD4, MRGPRX4, PIEZO1, MINDY4, KCNMA1, DUOX1, DAPK3, APEX1, CTH, CRY1, MRGPRX3, GAL3ST1, PTGES, AFP, CYP2C18, MYOCD, DLD, GGTLC1, PAH, HAP1, MIR146A, MBD2, CD44, UCP1, TXN, CD40LG, SULT1E1, ABCA1, TSC1, CX3CR1, ISYNA1, C5AR1, SERPINA3, PSMD9, MMP1, MAPK9, CLIC4, GGT1, NR1I2, S100A4, ROCK1, SUCNR1, SHMT1, SLC4A5, GDF2, CDH13, RYR2, PRKAB1, LIPC, PRKAA1, FGF1, ARHGEF40, CRK, DDR1, MIR130A, CAPN10, FABP3, FASN, BTN2A1, MBL2, BCHE, ACCS, CST12P, COX8A, FABP2, GRAP2, ASIC1, POLDIP2, BMP10, JAG1, CYP2C8, MIR17, IL33, CRMP1, VNN1, TNNI3, SLC9C1, UTRN, CD14, INSRR, FGB, TBX4, CXCL12, ATP1B1, ACSS2, AHSA1, CENPJ, PRCP, DDAH2, PADI4, MAPK14, EHMT1, BSND, PHA2A, SLPI, DENR, AIMP2, HNP1, EDN2, SLC9A1, PLA2G15, DNM1L, MALAT1, CLU, ADCYAP1, SESTD1, DMD, PHEX, SLC25A3, PFN1, PDE4D, JPH3, CNN1, PARP1, PECAM1, DIO2, TESC, P2RX3, MIR143, NUCB2, MPO, ITGB2, IAPP, SLC2A5, SLC35A1, DNMT1, SIK1, ADIPOR1, MPI, RNF19A, HTN3, VEGFC, VIP, EGR1, LBP, LAD1, CIMT, TNC, YAP1, PART1, SERPINF2, FOXO1, SLC5A4, RNF213, ADRA2C, CMKLR1, COMMD5, DHX40, ID2, HDAC9, MIR424, SMUG1, SULF2, USE1, HNF1A, SNAI1, AKR1B1, ZC3HC1, CLTRN, BCL2A1, SRM, ST2, BGLAP, ABCC8, POU2F3, TXN2, NOG, ULK3, SIRT6, NNT, PRDX2, DST, MIR518C, TBX1, SERPINA7, BMP2, ATP2B2, SV2C, IGF2BP2, TMED7-TICAM2, GGT2, GGTLC3, CPQ, WNT5A, GNA14, APC, VCL, SORBS1, UGT1A1, UQCRFS1, SLCO1B1, PDLIM5, GOSR2, ANXA5, SCGB1A1, ARSD, CD274, CNBP, PXDN, RHOBTB1, HBHR, FOXP3, ADRA1B, NR4A3, IL22, NOX3, ZGLP1, TMED7, GGTLC4P, TRPM7, ADORA2A, ADH1B, DEGS1, TUG1, CXCR4, NAMPT, SLC4A7, TWIST1, TFAM, TTR, MCM3AP, ALDH7A1, THBS4, B3GAT1, RN7SL263P, ATR, AKAP10, AMH, ABO, GPR182, SLC17A5, TGFA, MMRN1, SEPHS1, ERAL1, DKK1, FBXO8, ADAMTS13, SDS, C1QL1, TPT1, IMPACT, TSHR, TRPM2, GGTLC5P, SERPINC1, EBP, CRISP2, ATP2A2, MIR510, FOXRED1, NFAT5, NES, ANGPTL3, TNFRSF1A, TMSB4X, ABCG2, ARNTL, NECTIN1, PLN, MIR142, PRSS8, CD40, NLRC3, IL16, PRL, PRKCH, HBG2, HCRTR1, CD68, CD69, SLC9B2, ELK3, MS, PPP3R1, ARID3A, PTPA, TICAM2, ENTPD1, PSEN1, FSD1, ZBTB7C, AGXT2, CD5L, CD28, IFNB1, ETS1, PTGER4, PTGER1, PTGDS, COL17A1, FBL, ELANE, SETD3, PRSS55, BPIFB4, UBE2Z, CD38, FNDC1, NFYA, SMARCA4, ETV3, MIR23A, SERPINB2, PLEKHA7, SPZ1, MIR150, MIR221, CPB2, PEAR1, MIR22, TLX2, CCNL2, PDK1, CLCN6, NEFH, PDE3B, HPT, RETNLB, PCSK1, EPHB1, MIR25, NOX5, MIR26B, CDK6, SLC29A1, CDKN1A, NRG1, PPARD, EPHB6, FSD1L, EPHB2, HT, P2RY6, HLA-DRB1, PCSK6, MIR27B, PLXNA2, LRPAP1, MIR27A, PAEP, NFIL3, GSTM3, CCL5, SCT, SLC2A2, LGALS2, SHC1, HJV, IDE, SFTPC, SFRP5, GATA4, GCGR, GDNF, SDHB, SCPEP1, CCL21, GEM, GFAP, NPPC, CTSB, MAP6, SLC2A4, NPNT, HCCAT5, SLC22A2, SEMA6A, LRP1, BSG, BTF3P11, CYP4F3, SMAD2, FOSL2, MAOB, LIPA, FSHMD1A, TRIB3, FSHR, ARHGEF25, C1QTNF1, SLC3A1, GHRH, NPL, GHSR, FBRS, CAPN1, KCNJ13, GPR35, DHFR, RFC1, CYB5R3, RENBP, NTS, EFNB3, SLC39A12, OPN1LW, RCN2, CSMD1, GRN, CXCL1, GSR, MIR34A, OGG1, MIR192, DCN, NT5E, MIR126, LCT, IGAN1, SAI1, CTSL, KLKB1, RYR3, RYR1, MDK, LINC01194, GOLPH3, EFEMP1, GNA12, FABP1, CBLN2, SIK1B, SENP1, PADI1, CD300LG, APCDD1, TRPM5, GRHL1, GNPDA2, PSAT1, TDRD9, SLC26A9, MIR107, SLC22A12, MIR103A2, MIR100, MRPL4, ATL1, MIRLET7B, FIS1, GSTO2, CYP2R1, SOST, MAP3K15, CYCSP25, FOPNL, NDUFS7, LYPLAL1, BOLA3, TAS2R13, IL31RA, CD164L2, TRIM69, TRPM6, ARMS2, SRXN1, CACUL1, ENHO, KLK12, KCNIP3, RHOD, MYLIP, XPO5, TICAM1, CNTNAP2, EPHA6, SDK1, ADGRE4P, MARCHF8, LOC107987479, ZNF260, RXFP4, ATOH7, DLEU7, HYLS1, TSPAN33, NUPR1, ITGB1BP2, CPP, FOLH1B, SLC36A1, PABPC1, DNM3, GLCE, DROSHA, SLC29A4, NPW, LDOC1, PGP, IFNL2, IS1, BRD1, COL6A5, SLC24A2, KLK9, QPCT, GCA, CASC2, EBF3, FNDC5, VAMAS6, ADGRA2, SH2B1, CMYA5, FLCN, DCP1B, RLS1, LCE1C, RABGEF1, PCSK1N, AMOT, CBSL, SLC2A12, MCAT, CNTN4, SLCO4C1, RMDN2, FAM78B, REM1, IL23R, MOB3C, FLVCR1, RGCC, SLC35F3, PACERR, PAQR7, XIRP1, GPR162, CRPP1, NLRP6, GOLGA6A, MCIDAS, SNX5, HCAR1, CAVIN4, ADAMTS18, DDX53, CERNA3, TCEANC, LINC02210-CRHR1, PDCD4, SLC30A8, LCE1A, BMPER, RMDN1, CNTN5, C1QTNF6, PLXNA3, MTMR9, LGR4, WNK3, SAGE1, MIR30A, ACD, SLC30A10, POU5F1P4, SLC26A6, MIR31, MIR96, RNPC3, MIR33A, P2RY12, SYBU, POU5F1P3, MFSD1, PDIA2, MIR34B, GORASP1, STYK1, MIR585, MIR593, VKORC1, TTC21B, GSTCD, MSTO1, MCPH1, MIR296, PNPO, RMDN3, MIR637, ADIPOR2, SAP130, RCBTB1, MIR621, BHLHE41, PPP6R3, SLC29A3, MIR608, DRAM1, CARD14, TMEM38A, SLC48A1, MIR509-1, OXR1, HAMP, ZNF77, SLC2A9, MIR202, NGB, GRHL3, PLF, CISD2, SPHK2, MEPE, FAM20C, MIR506, MIR410, MIR425, MIR429, IBD7, PCBP4, MIR451A, BEND3, MIR431, VARS2, KCNQ5, IL21, MIR495, SLC5A7, MIR503, ARHGEF28, MIR499A, MIR98, MIR17HG, XYLT2, XYLT1, VPS11, TRIM67, PAG1, SLC28A3, SRR, GAS5, ANGPTL8, MIR328, PDGFC, BTNL2, SULT1A4, TRPV5, TREML2, MAP9, ANGPTL4, CCNQ, PPP1R14A, IL23A, MUC16, MIR132, MIR140, GHRL, PPR1, ASIC5, ORAI3, SLCO1C1, TSLP, CA14, TRIM47, GPR88, SOX18, MCU, WNT4, KNSTRN, TERF2IP, UCN2, PRRT2, OSER1, MRAP2, SFMBT1, HSPA14, MIR10A, C1QTNF3, PIPOX, GOLM1, MIR122, KCNK9, LOC102723407, CYGB, TLR8, TMEM54, MEX3C, BIRC6-AS1, GLCCI1, TAOK3, MIR4513, ANGPT4, IL17F, PRKAG2, SSH1, TAF7L, MIR222, CDKAL1, MIR200A, MIR200B, WBP1L, HDHD2, MIR206, EMILIN2, MIR1224, MIR543, MIR210, COL21A1, PTPN5, TUBB1, COASY, PDGFD, MIR212, FHOD3, RUBCNL, PTGES2, SVEP1, SLC52A1, CHCHD5, ERCC6L, HOPX, MIR19B1, SLX1A-SULT1A3, PPP1R9B, LINC01672, MIR185, MIR190A, ROBO4, SPATA6, KIF2B, MIR195, NDFIP2, MIR199A1, MIR199A2, CROT, ROPN1, ZGPAT, ALL2, NT5C1A, ALL1, TRPM4, A2M, SELL, AMACR, HNRNPD, HSPA1B, HSPA1A, AGFG1, HPX, HPV18I2, HPCAL1, HNRNPF, SLC29A2, HSPA2, HNF4A, NR4A1, HMOX2, HMGCR, HLA-C, HLA-A, UBE2K, HSPA1L, HSP90AA1, HDAC1, IGFALS, IL4R, IL2RA, IL2, IL1R1, CCN1, IGFBP3, IGFBP1, IFNA13, HTN1, IFNA2, IFNA1, IFI27, IDH2, IDH1, ID1, HTR1E, HDAC2, HBG1, CXCR1, FPR2, GATA3, GALNT2, GAD2, XRCC6, GAST, NR5A1, FXN, FPR1, GHR, FOSB, FOLH1, FLT4, FLI1, FOXO3, FOXM1, FOXC1, GC, GIP, HBA2, GSTM5, HBA1, GYS1, GYPE, GYPB, GYPA, GUCY1B1, GUCA2B, GSTA1, GLI2, GRIA1, GPX3, CXCR3, NPBWR1, GPI, GOT2, GLO1, IL5RA, IL10RA, OGN, MMP8, MTHFD1, MT1A, MSR1, MPV17, MPST, MMP12, MMP10, KMT2A, TRNI, MAP3K10, CXCL9, MET, MEST, MAP3K5, MEFV, ADAM11, MTR, MVD, MBP, NFATC3, NPY2R, NPHS1, NPC1, NPAS2, NOVA2, NHS, NFKB1, NEDD9, MX1, NDUFS4, NDUFA10, PPP1R12A, MYOC, MYL3, MYL2, MYH6, MC3R, MAT1A, IL10RB, PDX1, ITGB3, ITGAX, ITGAM, ITGA2, ISG20, IRF1, IRAK1, INHA, ITPR1, IMPA1, ILK, ILF3, IL15, IL13, IL12B, IL11, ITGB8, ITPR3, MAOA, LCN1, SMAD9, SMAD7, LSS, LRP5, LLGL2, LHCGR, LGALS1, KRT16, JUNB, KRT5, KIT, KIR3DL1, KIR2DS5, KCNN3, KCNH1, JUND, FHL2, FHL1, FGFR4, BMP7, C4BPA, C3AR1, BUB1B, KLF5, BRAF, BNIP1, BMPR1A, BGN, C5, BCL6, BCL2L1, BAAT, ATP7A, ATP6V0A1, ATP5F1B, ATP4A, CAPN5, CA2, ATP12A, CAV3, CDSN, CDR1, CDKN2B, CDH2, SCARB2, CD86, RUNX1T1, CASQ2, CACNA1A, CASP1, CAMK2A, CAMK4, CALD1, CALCR, CALB2, SLC25A20, ATP2B4, ATIC, FGFR1, ACVR2A, AMBP, ALOX15B, ALOX5AP, AHSG, NR0B1, AGXT, ADCYAP1R1, ACP3, AMY1B, ACO1, ACLS, ACHE, ASIC2, ACADSB, ABCA4, ABCA3, AMY1A, AMY1C, ART1, AQP5, ARSL, ARSB, ARRB1, PHOX2A, ARHGAP6, ARHGAP1, ARF6, FASLG, AOC2, APOH, APOC1, APOA4, BIRC3, APEH, APCS, APBB1, AKR1C4, CHGB, CHRM2, DSC3, EIF4E, EFNB2, EFNB1, LPAR1, E2F1, DUSP2, RCAN1, DPAGT1, ENO3, DNTT, DNMT3A, SARDH, DLG4, DIO1, DES, DBI, EMD, EPHA3, CHRM3, F8, FGF10, FDXR, FCGR2B, FBLN2, FANCD2, FABP4, F10, F2RL1, EPHA4, EYA3, ETV5, ESRRG, ERCC3, ERBB2, EPOR, EPHX1, DAG1, DAB2, CYP27B1, CCR7, COL9A1, COL8A1, COL4A2, COL1A2, CNP, CNN2, ABCC2, CCR3, CYP24A1, CLCN7, CLCN3, CLC, CISH, CIRBP, CHRNA4, CHRNA3, COL9A2, COL9A3, COMP, KLF6, CYP7A1, CYP4B1, CYP3A7, CYP2A6, CTSK, CTSG, CTRL, CTF1, CTBP1, CSF3, CRYZ, CREBBP, CLDN7, COX4I1, SLC31A1, ODC1, OPRD1, PSD4, CRLF1, SLC22A8, SLC22A6, TRIP10, NREP, KLF4, ASIC3, GPR37L1, MSC, TGFBRAP1, MTA2, XPR1, SLC28A2, HGS, P2RX6, RGN, USP2, COX5A, NTN1, PKD2L1, ARHGEF10, FIG4, RB1CC1, TOX, SLK, PPP6R2, GREB1, PHF14, ABCG1, NCR1, CARTPT, NPEPPS, ADAMTS1, ADAMTS4, HOMER1, GSTO1, MED23, ANGPTL1, NAT8, RABGAP1L, TAM, RGS20, TNFSF11, FCN3, AGPS, SEMA7A, FOXN1, AXIN2, LAP, TP63, PRRC2A, ST8SIA4, SCG2, IL1R2, NPHS2, YY1, XRCC1, PSMG1, AKR1C3, SOCS3, CCN4, F2RL3, KALRN, TRPA1, MGAM, WASF1, PER2, ALKBH1, TMEM11, IRS2, NRP1, HESX1, IL18RAP, TNFRSF10B, TNFSF14, RNGTT, MBTPS1, WASHC5, PUM3, OPRK1, MLXIP, KDM1A, FAIM2, PDCD11, SCAP, SIRT2, SACM1L, CARD8, ZNF652, TBC1D9, PTGDR2, POLI, CHEK2, RASSF1, SLC2A6, WDHD1, CORO1A, NCDN, ZCCHC14, PDIA5, TRS-AGA2-3, ATP6V0A2, RBFOX2, MMD, TRAM1, NPTXR, HEY1, SF3B3, MLYCD, LPIN1, SIRT5, WWC1, ADGRL3, CLEC16A, TASOR, NBEAL2, RRS1, YWHAQ, BTG3, RBM8A, CEBPZ, RAMP3, ABCC4, MSLN, GDF11, ANGPTL7, CALCRL, TSHZ1, BCAP31, BET1, PTPRU, NR1H3, HDAC5, SRA1, SLC12A6, FGFBP1, MVP, STUB1, APBB3, GPR75, DCTN6, FGL2, HPSE, WASF3, GJB6, AHCYL1, KDM5B, TNFSF13B, TXNIP, AKR1A1, HEXIM1, P3H4, ZNRD2, APPBP2, STK25, TFG, TLR6, XPC, NSD2, LAT2, PROS1, PTGDR, TAS2R38, PTBP1, PYY, PSMB8, PSG5, PSEN2, PRNP, PTPRO, PRKCG, PRH2, PRH1, SRGN, PRF1, PPP6C, PPP1CB, PTPRD, PXN, PPIB, RLN1, RRAS, RRAD, RPS6, RPL13, BRD2, RMRP, RLN2, RIEG2, RAC2, RHO, RGS1, REG1A, RBM4, RASA1, RAP1B, RAP1A, PPL, CTSA, VTN, PAM, PDE2A, PCYT1A, PCOS1, PCNA, PC, PAX5, CNTN3, PAK3, PDR, PAK1, P4HB, P2RY2, P2RX4, P2RX1, OTC, OPRM1, PDPK1, PEE1, POU5F1, PLAU, PON2, PODXL, EXOSC10, PLOD1, PLD2, PLCG1, PLCB3, PLAG1, PFKFB3, PLA2G5, PLA2G4A, PLA2G1B, PKM, PIN1, SERPINA1, PHB, S100A1, SORT1, SAA1, TBXA2R, TERT, TEK, TDO2, TCOF1, TCN2, TCF7L2, TBX3, TBX5, TG, TAP1, TAGLN, SYT1, SULT1A3, STAT5A, STAT1, TRIM21, TFRC, THRA, SAA2, UBTF, VIPR2, VDAC3, VDAC2, VDAC1, VAV2, VASP, UGCG, TTN, TIMP2, PHLDA2, TRV-AAC1-4, TRIO, HSP90B2P, TPH1, TPD52, TNFAIP3, SRY, SREBF1, SPRR2A, SDHC, SLC5A1, SLC4A1, SLC3A2, ST3GAL4, SI, SGCA, SEMA3F, SDC1, SPARC, CXCL5, CCL22, CCL13, CCL11, CCL7, SCN8A, SCD, SMTN, SLC6A9, SLC16A1, SLC19A1, SP1, SOS1, SORL1, SORD, SNX1, FSCN1, SNAP25, SMS, SMO, SMN2, SMN1, HLTF, SLC22A5, SLC22A4, SLC22A3, H3P23
  • Pattern Hair Loss Wikipedia
    "Trichoscopy: A new method for diagnosing hair loss". Journal of Drugs in Dermatology . 7 (7): 651–654. ... Classification D ICD - 10 : L64 MeSH : D000505 DiseasesDB : 7773 External resources MedlinePlus : 001177 eMedicine : derm/21 v t e Human hair Classification by type Lanugo Androgenic Terminal Vellus by location Body Ear Nose Eyebrow unibrow Eyelash Underarm Chest Abdominal Pubic Leg Head hairstyles ( list ) Afro Afro puffs Asymmetric cut Bald Bangs Beehive Big hair Blowout Bob cut Bouffant Bowl cut Braid Brush cut Bun ( odango ) Bunches Burr Businessman cut Butch cut Buzz cut Caesar cut Chignon Chonmage Chupryna Comb over Conk Cornrows Crew cut Crochet braids Croydon facelift Curly hair Curtained hair Devilock Dido flip Digital perm Dreadlocks Duck's ass Eton crop Extensions Feathered hair Finger wave Flattop Fontange French braid French twist Fringe Frosted tips Hair crimping Harvard clip High and tight Hime cut Historical Christian hairstyles Hi-top fade Induction cut Ivy League Jewfro Jheri curl Kiss curl Layered hair Liberty spikes Long hair Lob cut Marcelling Mod cut Mohawk Mullet 1950s 1980s Pageboy Part Payot Pigtail Pixie cut Polish halfshaven head Pompadour Ponytail Punch perm Princeton Professional cut Queue Quiff Rattail Razor cut Regular haircut Ringlets Shag Shape-Up Shimada Short back and sides Short brush cut Short hair Spiky hair Straight hair Standard haircut Surfer hair Taper cut Temple Fade Tonsure Updo Undercut Waves Widow's peak Wings Facial hair ( list ) Beard Chinstrap Goatee Shenandoah Soul patch Van Dyke Moustache Fu Manchu handlebar horseshoe pencil toothbrush walrus Designer stubble Sideburns Hair loss cosmetic Removal waxing threading plucking chemical electric laser IPL Shaving head leg cream brush soap Razor electric safety straight other Alopecia areata totalis universalis Frictional alopecia Male-pattern hair loss Hypertrichosis Management Trichophilia Trichotillomania Pogonophobia Haircare products Brush Clay Clipper Comb Conditioner Dryer Gel Hot comb Iron Mousse Pomade Relaxer Rollers Shampoo Spray Wax Haircare techniques Backcombing Crimping Curly Girl Method Hair cutting Perm Shampoo and set Straightening Related topics Afro-textured hair ( kinky hair ) Beard and haircut laws by country Bearded lady Barber ( pole ) Eponymous hairstyle Frizz Good hair Hairdresser Hair fetishism ( pubic ) Hair follicle Hair growth Hypertrichosis Trichotillomania v t e Diseases of the skin and appendages by morphology Growths Epidermal Wart Callus Seborrheic keratosis Acrochordon Molluscum contagiosum Actinic keratosis Squamous-cell carcinoma Basal-cell carcinoma Merkel-cell carcinoma Nevus sebaceous Trichoepithelioma Pigmented Freckles Lentigo Melasma Nevus Melanoma Dermal and subcutaneous Epidermal inclusion cyst Hemangioma Dermatofibroma (benign fibrous histiocytoma) Keloid Lipoma Neurofibroma Xanthoma Kaposi's sarcoma Infantile digital fibromatosis Granular cell tumor Leiomyoma Lymphangioma circumscriptum Myxoid cyst Rashes With epidermal involvement Eczematous Contact dermatitis Atopic dermatitis Seborrheic dermatitis Stasis dermatitis Lichen simplex chronicus Darier's disease Glucagonoma syndrome Langerhans cell histiocytosis Lichen sclerosus Pemphigus foliaceus Wiskott–Aldrich syndrome Zinc deficiency Scaling Psoriasis Tinea ( Corporis Cruris Pedis Manuum Faciei ) Pityriasis rosea Secondary syphilis Mycosis fungoides Systemic lupus erythematosus Pityriasis rubra pilaris Parapsoriasis Ichthyosis Blistering Herpes simplex Herpes zoster Varicella Bullous impetigo Acute contact dermatitis Pemphigus vulgaris Bullous pemphigoid Dermatitis herpetiformis Porphyria cutanea tarda Epidermolysis bullosa simplex Papular Scabies Insect bite reactions Lichen planus Miliaria Keratosis pilaris Lichen spinulosus Transient acantholytic dermatosis Lichen nitidus Pityriasis lichenoides et varioliformis acuta Pustular Acne vulgaris Acne rosacea Folliculitis Impetigo Candidiasis Gonococcemia Dermatophyte Coccidioidomycosis Subcorneal pustular dermatosis Hypopigmented Tinea versicolor Vitiligo Pityriasis alba Postinflammatory hyperpigmentation Tuberous sclerosis Idiopathic guttate hypomelanosis Leprosy Hypopigmented mycosis fungoides Without epidermal involvement Red Blanchable Erythema Generalized Drug eruptions Viral exanthems Toxic erythema Systemic lupus erythematosus Localized Cellulitis Abscess Boil Erythema nodosum Carcinoid syndrome Fixed drug eruption Specialized Urticaria Erythema ( Multiforme Migrans Gyratum repens Annulare centrifugum Ab igne ) Nonblanchable Purpura Macular Thrombocytopenic purpura Actinic/solar purpura Papular Disseminated intravascular coagulation Vasculitis Indurated Scleroderma / morphea Granuloma annulare Lichen sclerosis et atrophicus Necrobiosis lipoidica Miscellaneous disorders Ulcers Hair Telogen effluvium Androgenic alopecia Alopecia areata Systemic lupus erythematosus Tinea capitis Loose anagen syndrome Lichen planopilaris Folliculitis decalvans Acne keloidalis nuchae Nail Onychomycosis Psoriasis Paronychia Ingrown nail Mucous membrane Aphthous stomatitis Oral candidiasis Lichen planus Leukoplakia Pemphigus vulgaris Mucous membrane pemphigoid Cicatricial pemphigoid Herpesvirus Coxsackievirus Syphilis Systemic histoplasmosis Squamous-cell carcinoma v t e Disorders of skin appendages Nail thickness: Onychogryphosis Onychauxis color: Beau's lines Yellow nail syndrome Leukonychia Azure lunula shape: Koilonychia Nail clubbing behavior: Onychotillomania Onychophagia other: Ingrown nail Anonychia ungrouped: Paronychia Acute Chronic Chevron nail Congenital onychodysplasia of the index fingers Green nails Half and half nails Hangnail Hapalonychia Hook nail Ingrown nail Lichen planus of the nails Longitudinal erythronychia Malalignment of the nail plate Median nail dystrophy Mees' lines Melanonychia Muehrcke's lines Nail–patella syndrome Onychoatrophy Onycholysis Onychomadesis Onychomatricoma Onychomycosis Onychophosis Onychoptosis defluvium Onychorrhexis Onychoschizia Platonychia Pincer nails Plummer's nail Psoriatic nails Pterygium inversum unguis Pterygium unguis Purpura of the nail bed Racquet nail Red lunulae Shell nail syndrome Splinter hemorrhage Spotted lunulae Staining of the nail plate Stippled nails Subungual hematoma Terry's nails Twenty-nail dystrophy Hair Hair loss / Baldness noncicatricial alopecia : Alopecia areata totalis universalis Ophiasis Androgenic alopecia (male-pattern baldness) Hypotrichosis Telogen effluvium Traction alopecia Lichen planopilaris Trichorrhexis nodosa Alopecia neoplastica Anagen effluvium Alopecia mucinosa cicatricial alopecia : Pseudopelade of Brocq Central centrifugal cicatricial alopecia Pressure alopecia Traumatic alopecia Tumor alopecia Hot comb alopecia Perifolliculitis capitis abscedens et suffodiens Graham-Little syndrome Folliculitis decalvans ungrouped: Triangular alopecia Frontal fibrosing alopecia Marie Unna hereditary hypotrichosis Hypertrichosis Hirsutism Acquired localised generalised patterned Congenital generalised localised X-linked Prepubertal Acneiform eruption Acne Acne vulgaris Acne conglobata Acne miliaris necrotica Tropical acne Infantile acne / Neonatal acne Excoriated acne Acne fulminans Acne medicamentosa (e.g., steroid acne ) Halogen acne Iododerma Bromoderma Chloracne Oil acne Tar acne Acne cosmetica Occupational acne Acne aestivalis Acne keloidalis nuchae Acne mechanica Acne with facial edema Pomade acne Acne necrotica Blackhead Lupus miliaris disseminatus faciei Rosacea Perioral dermatitis Granulomatous perioral dermatitis Phymatous rosacea Rhinophyma Blepharophyma Gnathophyma Metophyma Otophyma Papulopustular rosacea Lupoid rosacea Erythrotelangiectatic rosacea Glandular rosacea Gram-negative rosacea Steroid rosacea Ocular rosacea Persistent edema of rosacea Rosacea conglobata variants Periorificial dermatitis Pyoderma faciale Ungrouped Granulomatous facial dermatitis Idiopathic facial aseptic granuloma Periorbital dermatitis SAPHO syndrome Follicular cysts " Sebaceous cyst " Epidermoid cyst Trichilemmal cyst Steatocystoma simplex multiplex Milia Inflammation Folliculitis Folliculitis nares perforans Tufted folliculitis Pseudofolliculitis barbae Hidradenitis Hidradenitis suppurativa Recurrent palmoplantar hidradenitis Neutrophilic eccrine hidradenitis Ungrouped Acrokeratosis paraneoplastica of Bazex Acroosteolysis Bubble hair deformity Disseminate and recurrent infundibulofolliculitis Erosive pustular dermatitis of the scalp Erythromelanosis follicularis faciei et colli Hair casts Hair follicle nevus Intermittent hair–follicle dystrophy Keratosis pilaris atropicans Kinking hair Koenen's tumor Lichen planopilaris Lichen spinulosus Loose anagen syndrome Menkes kinky hair syndrome Monilethrix Parakeratosis pustulosa Pili ( Pili annulati Pili bifurcati Pili multigemini Pili pseudoannulati Pili torti ) Pityriasis amiantacea Plica neuropathica Poliosis Rubinstein–Taybi syndrome Setleis syndrome Traumatic anserine folliculosis Trichomegaly Trichomycosis axillaris Trichorrhexis ( Trichorrhexis invaginata Trichorrhexis nodosa ) Trichostasis spinulosa Uncombable hair syndrome Wooly hair nevus Sweat glands Eccrine Miliaria Colloid milium Miliaria crystalline Miliaria profunda Miliaria pustulosa Miliaria rubra Occlusion miliaria Postmiliarial hypohidrosis Granulosis rubra nasi Ross’ syndrome Anhidrosis Hyperhidrosis Generalized Gustatory Palmoplantar Apocrine Body odor Chromhidrosis Fox–Fordyce disease Sebaceous Sebaceous hyperplasia
    SRD5A2, AR, ABCC2, SUPV3L1, VDR, ZFP36, MTHFR, TNFRSF10A, BRD4, ZDHHC13, HR, PRKAR1A, CRH, PARP1, RHOA, WNT10A, C1orf127, FAF1, MKLN1-AS, TBX15, HOXD-AS2, ARL17B, LINC01432, SSPN, SLC14A2, FAM53B, EMC2, HDAC9, EDAR, MAPT-AS1, DRAIC, DKK2, KLF15, MEMO1, RSPO2, KANSL1, MRPS22, LINC00670, LRMDA, OFCC1, DPY30, GORAB, SPPL2C, THADA, GORAB-AS1, EBF1, RUNX1, MAPT, MKLN1, EIF3E, OPHN1, IRF4, FGF5, AGA, EDA2R, KLK3, TGFB1, GGCT, CD200, DKK1, CTNNB1, IGF1, CD34, DPP4, CYP27B1, COX8A, CRP, COL17A1, CARD14, PRNP, NLRP3, FGF2, CDKN2A, MS4A1, CASP3, C4BPA, MIR223, MIR451A, MIR146B, BDNF, XIAP, AGXT, AGT, AKR1C4, IL1B, KRT20, VEGFA, PTPN1, SHBG, SRD5A1, PPARA, ABCB1, OTC, PRDX2, TGFB1I1, TLR4, TNF, TP53, WNT10B, GHR, NFE2L2, NCOA4, LEP, KRT5, ABCB6, DHRS9, IL17A, MMRN1, TBC1D9, PTGDS, HPGDS, TGFBR1
    • Alopecia, Androgenetic, 1 Omim
      Description Androgenetic alopecia is characterized by a loss of hair from the scalp that follows a defined pattern (Hamilton, 1951). It occurs in women as well as in men. It is caused by a shortening of the anagen (growth) phase and miniaturization of the hair follicle, which results in the formation of progressively thinner, shorter hair (Bergfeld, 1995). In men, the condition is often referred to as male pattern baldness (MPB) and appears to be androgen-dependent (Hamilton, 1942). The condition is hereditary, and follows a pattern that may be consistent with an autosomal dominant trait (Osborn, 1916). Linkage evidence for an autosomal locus on 3q26 (AGA1) has been identified (Hillmer et al., 2008).
    • Androgenetic Alopecia Medlineplus
      Androgenetic alopecia is a common form of hair loss in both men and women. In men, this condition is also known as male-pattern baldness. Hair is lost in a well-defined pattern, beginning above both temples. Over time, the hairline recedes to form a characteristic "M" shape. Hair also thins at the crown (near the top of the head), often progressing to partial or complete baldness. The pattern of hair loss in women differs from male-pattern baldness. In women, the hair becomes thinner all over the head, and the hairline does not recede.
  • Familial Hemiplegic Migraine Wikipedia
    Minor head trauma is a common attack precipitant, so FHM sufferers should avoid contact sports. Acetazolamide or standard drugs are often used to treat attacks, though those leading to vasoconstriction should be avoided due to the risk of stroke .
    ATP1A2, CACNA1A
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