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  • Runner's Diarrhea Wikipedia
    Methods to prevent runner's diarrhea will vary between individuals, although it is advisable to consider examining the pre-running diet to determine potential trigger foods. [1] Notable cases [ edit ] At the 1998 London Marathon , winner Catherina McKiernan suffered from recurrent diarrhea during the race. [4] At the 2005 London Marathon, winner Paula Radcliffe , in desperate need for a toilet break during the race, stopped by the road in full view of the crowd and live TV cameras and defecated. She later blamed a surfeit of pasta and grilled salmon from the previous night for the incident. [5] At the 2008 Göteborgsvarvet half marathon, David Bailey finished the race in 21st place in spite of being stained with his own excrement.
  • Visual Snow Wikipedia
    Medications that may be used to treat the condition include lamotrigine , acetazolamide , or verapamil . [4] These do not always result in benefits, however. [3] [2] Contents 1 Signs and symptoms 1.1 Comorbidities 2 Causes 3 Diagnosis 4 Treatments 5 References 6 External links Signs and symptoms [ edit ] Clear vision versus disturbed vision People report seeing "snow", much like the visual noise or "static" on a TV screen after transmission ends. In a 2010 study Raghaven et al. hypothesize that what the patients see as "snow" is their own intrinsic eigengrau . [7] Many report more visual snow in low light conditions. ... PMID 12609692 . ^ Schankin, Christoph J.; Maniyar, Farooq H.; Digre, Kathleen B.; Goadsby, Peter J. (2014-03-18). " ' Visual snow' – a disorder distinct from persistent migraine aura" .
  • Gelotophobia Wikipedia
    Paul Lewis (Boston College, US) speculated whether political gelotophobia might affect elections in the US ("The twin fears of being effectively mocked or ineffective in mocking others [too harsh, blunt, tasteless] led candidates to aggressive and proactive strategies [going on TV to show they can take a joke, be funny—anything to avoid being rendered pathetically ridiculous or inappropriately derisive]") [p. 42, conference abstract from the 2009 conference of the International Society for Humor Studies ISHS in Long Beach, California]; [17] Sociologist Christie Davies , who is also president of the ISHS, comments satirically on the results of recent elections in the UK. ... Humor . 22 (1–2). doi : 10.1515/humr.2009.003 . ^ Weiss, Elisabeth M.; Schulter, Günter; Freudenthaler, H. Harald; Hofer, Ellen; Pichler, Natascha; Papousek, Ilona (2012-05-31). ... Humor , 22 , 91-110. ^ Papousek, I., Ruch, W., Freudenthaler, H. H., Kogler, E., Lang, B., & Schulter, G. (2009).
  • Body Inflation Wikipedia
    Blowup, [1] who appears in the Deviant Desires book. [2] He wears air-inflated double-skinned latex suits, and has made a number of TV appearances in the UK, including Eurotrash . [3] Sometimes the body is actually inflated also, such as by enema or drinking large amounts of liquid.
  • Trypophobia Wikipedia
    A significant minority of those with trypophobia meet the DSM-5 criteria for obsessive–compulsive disorder. [3] Martínez-Aguayo et al. stated that other findings refer to trypophobia having common comorbid psychiatric diagnosis, such as major depressive disorder or generalized anxiety disorder , although Le et al. felt that general anxiety does not cause trypophobia. [3] Treatment [ edit ] There are no known treatments for trypophobia, but exposure therapy , which has been used to treat phobias, is likely to be effective for treating trypophobia. [1] Epidemiology [ edit ] The extent to which trypophobia exists is unknown, [1] but the available data suggests that having an aversion to trypophobic imagery is relatively common. [1] [2] [3] 16% of a sample of 286 participants in a 2013 study reported discomfort or repulsion when presented with an image of a lotus seed pod and its authors found that non-trypophobic individuals also experienced more discomfort when viewing trypophobic imagery than when viewing neutral images. [1] Trypophobia appears to be more prevalent in women. [3] Society and culture [ edit ] The term trypophobia is believed to have been coined by a participant in an online forum in 2005. [5] The word is from the Greek : τρῦπα , trŷpa , meaning "hole" and φόβος , phóbos , meaning "fear". [5] Groups on social media sites such as Facebook and Instagram exist for self-identified trypophobics to share and discuss images that they say induce the reaction. [5] [11] Because trypophobia is not well known to the general public, many people with the condition do not know the name for it and believe that they are alone in their trypophobic reactions and thoughts until they find an online community to share them with. [12] This has led to an increase in trypophobic images on social media; in some cases, people seek to intentionally induce trypophobia in those who have it by showing them trypophobic images, with the most trypophobic-inducing images being holes and clusters (especially the lotus seedhead) photoshopped onto human skin. [12] Cole and Wilkins also stated that the level of disgust with trypophobia increases if the holes are on human skin. [12] Writing in Popular Science , Jennifer Abbasi argues that emotional contagion within such social media groups may be responsible for some of the aversive reactions to such images. [5] In 2017, trypophobia received media attention when American Horror Story featured a trypophobic character [13] and trypophobia-inducing advertisements promoting the storyline; some people were disturbed by the imagery, [12] [14] and criticized the show for "insensitivity towards sufferers of trypophobia". [14] Although there was sentiment that the increased media attention could lead to people trying to induce trypophobia, there were also opinions that it might help people understand trypophobia and encourage more research on the matter. [12] Some users responded to the September 2019 release of Apple's iPhone 11 Pro , which features three closely spaced camera lenses, with comments that it triggered their trypophobia. [15] Writer and editor Kathleen McAuliffe suggested that trypophobia is yet to be extensively studied because researchers have not given as much attention to topics of disgust as they have to other areas of research, and because of the revulsion viewing the images could incite in researchers. [16] See also [ edit ] List of phobias References [ edit ] ^ a b c d e f g h i j k l Milosevic, Irena; McCabe, Randi E. (2015). ... Retrieved October 25, 2017 . ^ a b c d e f g h i j k l m n o p q r s t u v w Martínez-Aguayo, Juan Carlos; Lanfranco, Renzo C.; Arancibia, Marcelo; Sepúlveda, Elisa; Madrid, Eva (2018). ... Retrieved 10 Apr 2016 . ^ a b c d e LaMottef, Sandee (September 14, 2017). "TV show triggers little-known phobia" .
  • Ruminal Tympany Wikipedia
    This same accident was portrayed in the TV Series of the same name , but with Farmer Skerry striking a match to light his cigarette as James' colleague Tristan releases the gas.
  • Ortner's Syndrome Wikipedia
    S2CID 46119392 . ^ a b Condon LM, Katkov H, Singh A, Helseth HK (July 1985). ... PMID 2796367 . ^ a b Subramaniam V, Herle TV, Mohammed N, Thahir M (October 2011).
  • Möbius Syndrome Wikipedia
    In the first season of American medical drama The Good Doctor , a teenage patient is depicted with Möbius syndrome. In the BBC TV series Face , Loraine Deveney, a Möbius syndrome patient, was portrayed as a successful example of "smile surgery" performed by R. M. Zuker, M.D. The German TV series Dr. Stefan Frank episode "Ein himmlisches Lächeln" (season 4, episode 4) is about a young boy living with Möbius syndrome. ... Münchener Medizinische Wochenschrift . 35 : 91–4. ^ Al Kaissi A, Grill F, Safi H, Ben Ghachem M, Ben Chehida F, Klaushofer K (2007).
    REV3L, PLXND1
    • Moebius Syndrome OMIM
      Description The most basic description of Moebius syndrome is a congenital facial palsy with impairment of ocular abduction. The facial nerve (cranial nerve VII) and abducens nerve (CN VI) are most frequently involved, but other cranial nerves may be involved as well. Other variable features include orofacial dysmorphism and limb malformations. Mental retardation has been reported in a subset of patients. Most cases of Moebius syndrome are sporadic, but familial occurrence has been reported (Verzijl et al., 2003). The definition of and diagnostic criteria for Moebius syndrome have been controversial and problematic.
    • Moebius Syndrome GARD
      Moebius syndrome is a rare neurological condition that primarily affects the muscles that control facial expression and eye movement. Signs and symptoms of the condition may include weakness or paralysis of the facial muscles; feeding, swallowing, and choking problems; excessive drooling; crossed eyes; lack of facial expression; eye sensitivity; high or cleft palate; hearing problems; dental abnormalities; bone abnormalities in the hands and feet; and/or speech difficulties. Affected children often experience delayed development of motor skills (such as crawling and walking), although most eventually acquire these skills. Moebius syndrome is caused by the absence or underdevelopment of the 6th and 7th cranial nerves , which control eye movement and facial expression. Other cranial nerves may also be affected. There is no cure for Moebius syndrome, but proper care and treatment give many individuals a normal life expectancy.
  • Werner Syndrome Wikipedia
    PMID 3909762 . ^ a b Hasty P, Campisi J, Hoeijmakers J, van Steeg H, Vijg J (2003). "Aging and genome maintenance: lessons from the mouse?". ... Available from: https://www.ncbi.nlm.nih.gov/books/NBK1514/ ^ Goto M, Miller RW, Ishikawa Y, Sugano H (1996). "Excess of rare cancers in Werner syndrome (adult progeria)". ... PMC 3040982 . PMID 20934517 . ^ a b c d e f g h Goto, Makoto (2004). Clinical Aspects of Werner's Syndrome: Its Natural History and the Genetics of the Disease . ... PMID 5431223 . ^ Salk D, Au K, Hoehn H, Martin GM (1981). "Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism". ... PMID 2762303 . ^ a b Crabbe L, Jauch A, Naeger CM, Holtgreve-Grez H, Karlseder J (2007). "Telomere dysfunction as a cause of genomic instability in Werner syndrome" .
    WRN, BLM, HFM1, TP53, PARP1, RECQL4, LMNA, SERPINE1, FEN1, RAD51, POLB, XRCC6, IGFBP3, FN1, AHSA1, PRKAR1A, H2AX, GRAP2, PCNA, RECQL5, MRE11, XRCC5, EFEMP1, TGFB1, RECQL, MLH1, AIMP2, GYPA, MAPK1, ATR, WRNIP1, RNF19A, CRK, MAPK14, POLDIP2, SLC35G1, TAGLN, RAC1, MIR200C, CHD9, TFRC, APLF, BRIP1, TERT, GTF2IRD2, RPS3, PIWIL4, SSRP1, TOP3A, SLC20A1, SLC2A1, RPS6KA3, TIMP1, MON2, NEIL1, SIRT6, MMRN1, SAMHD1, RBPMS, PRPF19, DDX46, POLL, DESI1, EXD3, ENOSF1, ADIPOQ, PIWIL1, EXO1, CES2, DHX16, RAD54L, DDX19A, SUMO1, ABL1, PPP2CB, PPARG, GOLGA3, GCK, MTOR, FGFR1, FANCD2, EWSR1, ERCC4, ERCC1, DNA2, DKC1, DHX9, ACE, DCN, COL3A1, CKMT2, CDKN2A, CDC42, CAT, CASP1, CALCA, BRCA1, ATM, APOA1, APEX1, ANK1, HOXA@, HOXA1, HOXA3, KDR, POU1F1, POLD1, PLIN1, PLG, ACTB, OGG1, NBN, MYC, MECP2, MBNL1, LIG4, INSR, HOXA4, IL1B, IL1A, IGF2, ICAM1, HOXA13, HOXA11, HOXA10, HOXA9, HOXA7, HOXA6, HOXA5, H3P10
    • Werner Syndrome GeneReviews
      TFAP2A is the only gene in which pathogenic variants are currently known to cause this autosomal dominant condition. SHORT syndrome ( s hort stature, h yperextensibility, h ernia, o cular depression, R ieger anomaly, and t eething delay) may include progeria-like facies and lipodystrophy.
    • Werner Syndrome OMIM
      A number sign (#) is used with this entry because Werner syndrome is caused by homozygous or compound heterozygous mutation in the RECQL2 gene (604611), which encodes a homolog of the E. coli RecQ DNA helicase, on chromosome 8p12. See also Hutchinson-Gilford progeria syndrome (HGPS; 176670), a more severe progeroid syndrome with earlier onset caused by mutation in the LMNA gene (150330). Clinical Features The features of Werner syndrome are scleroderma-like skin changes, especially in the extremities, cataract, subcutaneous calcification, premature arteriosclerosis, diabetes mellitus, and a wizened and prematurely aged facies. A particularly instructive pedigree was reported by McKusick (1963). The habitus is characteristic, with short stature, slender limbs, and stocky trunk. The nose is beaked. Epstein et al. (1966) studied a Japanese patient living in Seattle.
    • Werner Syndrome Orphanet
      Werner syndrome (WS) is a rare inherited syndrome characterized by premature aging with onset in the third decade of life and with cardinal clinical features including bilateral cataracts, short stature, graying and thinning of scalp hair, characteristic skin disorders and premature onset of additional age-related disorders. Epidemiology The prevalence among Japanese and Sardinian populations is estimated to be 1/50,000 due to the presence of founder mutations. Prevalence in other populations is unknown, but may be around 1/200,000. Clinical description WS patients are normal at birth and during childhood, apart from the absence of a pubertal growth spurt. WS presents between the ages of 20 and 30 with major symptoms of early onset bilateral cataracts, thinning and graying of the hair, short stature and skin changes (ankle ulceration, hyperkeratosis, tight skin, age spots, ''bird-like'' facies and subcutaneous atrophy).
    • Werner Syndrome MedlinePlus
      Werner syndrome is characterized by the dramatic, rapid appearance of features associated with normal aging. Individuals with this disorder typically grow and develop normally until they reach puberty. Affected teenagers usually do not have a growth spurt, resulting in short stature. The characteristic aged appearance of individuals with Werner syndrome typically begins to develop when they are in their twenties and includes graying and loss of hair; a hoarse voice; and thin, hardened skin. They may also have a facial appearance described as "bird-like." Many people with Werner syndrome have thin arms and legs and a thick trunk due to abnormal fat deposition.
    • Werner Syndrome GARD
      Werner syndrome is a condition that causes premature aging. People with this syndrome will develop and grow normally until puberty. At puberty, growth stops and adults with Werner syndrome are typically shorter than average. By the early 20s-30s, people with this syndrome develop conditions usually associated with more advanced ages. In addition, people with Werner syndrome have an increased risk of developing cancer, especially thyroid and skin cancers. Heart attack and cancer are the most common causes of death. Werner syndrome is caused by mutations in the WRN gene and is inherited in an autosomal recessive manner.
  • Survivor Guilt Wikipedia
    Fox ) goes to a therapist to deal with his own survivor's guilt after a friend is killed in a car crash while running an errand that Alex refused to help with. The TV series Rescue Me follows the lives of firefighters post 9/11 in New York City , focusing on Tommy Gavin , a 9/11 first responder experiencing severe survivor guilt over the civilians he was unable to save and the other firefighters who died in the attack, many of whom he personally knew. ... Spooner has survivor's guilt. In the TV show Arrow , the main character, Oliver Queen, has survivor's guilt in the episode "Three Ghost". ... The light novel sequel to the 5th part of the long-running manga series JoJo's Bizarre Adventure called Purple Haze Feedback has Pannacotta Fugo, a character from the beginning of the part who left the main cast in the main part when they went to fight the main villain, become distraught after learning of the deaths of three of his old comrades who joined the main fight and wonders why he didn't join them. In an episode of TV show " Hawaii Five-0 ", Danny Williams mentions that his life since the September 11 attacks is all "borrowed time", when he and his then-partner Grace Tillwell raided a gang warehouse (without having told anyone about it) in the early morning hours of September 11, 2001, and were tortured by the gang members, who then killed his partner, and were about to proceed on him before being distracted by the sound of sirens outside, allowing Danny to break free and kill the gang members, before running outside to try and flag down a police car, only to see them speeding towards a huge billow of dark smoke.
  • Fear Of Bees Wikipedia
    Archived 2007-07-02 at the Wayback Machine a transcript from Impact Television, a weekly TV series by University of Florida ^ Bee or Yellow Jacket Stings Archived 2006-12-13 at the Wayback Machine , a hospital advise ^ "The Birds, the Bees, and the Flying Foxes: Pollinators in Jeopardy" (PDF) .
  • Haemolacria Wikipedia
    Contents 1 History 2 See also 3 References History [ edit ] Twinkle Dwivedi From Lucknow , India , Dwivedi presented a rare condition that appeared to cause her to spontaneously bleed from her eyes and other parts of her body without presenting any visible wounds. [3] Dwivedi was the subject of numerous medical research studies and TV shows including Body Shock [4] and a National Geographic documentary. [5] In the absence of a medical explanation for her condition, some religious explanations have been posed.
  • Ronnie And Donnie Galyon Wikipedia
    Oldest conjoined twins Ronnie and Donnie Galyon Born Ronald Galyon Donald Galyon ( 1951-10-28 ) October 28, 1951 Dayton, Ohio Died July 4, 2020 (2020-07-04) (aged 68) Dayton, Ohio Occupation Sideshow attractions, reality TV personalities Known for Oldest living set of conjoined twins Ronnie and Donnie Galyon (October 28, 1951 – July 4, 2020) [1] were American conjoined twins .
  • Party And Play Wikipedia
    In an article published by The Guardian , it has been argued that an exaggerated reporting might give the public a distorted impression of the magnitude of this phenomenon – and that can only increase the level of collective anxiety. [25] See also [ edit ] LGBT portal Human sexuality portal Bugchasing Group sex HIV superinfection LGBT slang Sex and drugs Chemsex (documentary film) References [ edit ] ^ a b "PSA tackles PNP : TV ad warns against crystal meth usage in the gay male community" . metroweekly.com . 2007-09-21. ... Retrieved 2018-06-11 . ^ a b c d e f g h San Francisco Meth Zombies (TV documentary).
  • Gnathostomiasis Wikipedia
    ISBN 0-7216-2921-0 . ^ a b c d e f g h i j David T. John; William A. Petri (2006). ... PMID 11023048 . ^ Setasuban P; Nuamtanong S; Rojanakittikoon V; Yaemput S; Dekumyoy P; Akahane H; Kojima S. (1991). "Gnathostomiasis in Thailand: a survey on intermediate hosts of Gnathostoma spp. with special reference to a new type of larvae found in Fluta alba ". Southeast Asian J Trop Med Public Health . 22 Suppl: 220–4. PMID 1822890 . ^ Akahane H, Setasuban P, Nuamtanong S, Horiuchi S, Koga M, Kojima S (1995). ... S2CID 24447639 . ^ Sieu TP, Dung TT, Nga NT, Hien TV, Dalsgaard A, Waikagul J, Murrell KD (Feb 2009). ... Cockman-Thomas; Curtis A. Colleton; Chris H. Gardiner; Wayne M. Meyers (1993).
    LGALS3BP, COX1, PDR, PPIG, AMZ1
  • Prader–willi Syndrome Wikipedia
    Revista Médica de Chile . 133 (1): 33–41. doi : 10.4067/s0034-98872005000100005 . PMID 15768148 . ^ a b c d e f g h i j k l m n o "Prader-Willi syndrome" . ... PMID 12091883 . S2CID 5253679 . ^ Clark DJ, Boer H, Webb T (1995). "General and behavioural aspects of PWS: a review". ... Archived from the original on June 29, 2014. ^ Davies PS, Evans S, Broomhead S, Clough H, Day JM, Laidlaw A, Barnes ND (May 1998). ... PMID 11932286 . ^ Höybye C, Hilding A, Jacobsson H, Thorén M (May 2003). "Growth hormone treatment improves body composition in adults with Prader-Willi syndrome". ... Retrieved June 12, 2009 . ^ "Extreme Makeover: Home Edition Articles on AOL TV" . Aoltv.com. Archived from the original on September 23, 2015 .
    MAGEL2, SNRPN, NDN, MKRN3, NPAP1, IPW, PWAR1, SNORD116-1, MKRN3-AS1, PWRN1, SNORD115-1, MRAP2, HERC2, HTR2C, CEP63, CENPJ, SOS1, PTPN11, RIT1, KRAS, RAF1, LZTR1, ATR, GH1, UBE3A, GABRB3, SNORD116@, UROD, SNURF, LEP, SNORD14D, SNORD14B, SNORD35B, SNORD14E, SNORD14C, GHRL, SNORD15A, IGF1, HCRT, GHR, SLC52A2, OCA2, F2R, NR1I2, ADIPOQ, PCSK1, ATP10A, POMC, SETDB1, IL6, GHRH, SNHG14, MAGED1, PWAR5, DMD, BEST1, ZNF274, FMR1, GNAQ, GLP1R, EHMT1, STOML3, HSPG2, STS, RASA1, TNFSF11, CRP, SLC6A4, LEPR, MARK2, TNFRSF11B, EHMT2, METAP2, NHLH2, GHSR, GABRA5, SOST, SIM1, PIK3CA, DKK1, PROCR, PADI4, EID1, RNF13, CIT, ABCB6, GREM1, CYFIP1, ACADS, ADIPOR1, RCBTB1, ZGLP1, MIR23A, MIR122, GOLGA8EP, RBMY1D, ENHO, PWARSN, RBMY2DP, GOLGA6A, WHAMMP3, SNORD109B, SNORD109A, NIPA1, TUBGCP5, LMLN, TMPRSS13, NIPA2, DHDDS, POM121, ADIPOR2, ANKRD36B, CHPT1, PRDM9, RETN, NSMCE3, ANGPTL8, ZNF654, DHX40, SMN2, PREPL, MSMB, MECP2, STMN1, HTR2B, HTC2, NR4A1, HDC, GCG, GAPDH, GABRG3, FRAXA, FMO2, EPHB1, EFNB2, DIO3, DAZ1, DAG1, CNR1, CD36, BTF3P11, BRAF, BGLAP, BDNF, BCR, AVP, ARSD, ARSA, AR, APOC3, ALCAM, MEN1, MST1, DLK1, CYTB, SCG2, VEGFA, TYR, TWIST1, TSPY1, TNF, THAS, STATH, STAR, AGRP, SMN1, SLC5A2, CCL5, SAG, RBMY1A1, PYY, PRNP, PRL, PRKCA, PTPA, PML, PIK3CG, PIK3CD, PIK3CB, PGC, PDPK1, NPY2R, NPY, HNRNPM, FMR1-IT1
    • Prader-Willi Syndrome GeneReviews
      Summary Clinical characteristics. Prader-Willi syndrome (PWS) is characterized by severe hypotonia and feeding difficulties in early infancy, followed in later infancy or early childhood by excessive eating and gradual development of morbid obesity (unless eating is externally controlled). Motor milestones and language development are delayed. All individuals have some degree of cognitive impairment. A distinctive behavioral phenotype (with temper tantrums, stubbornness, manipulative behavior, and obsessive-compulsive characteristics) is common. Hypogonadism is present in both males and females and manifests as genital hypoplasia, incomplete pubertal development, and, in most, infertility. Short stature is common (if not treated with growth hormone); characteristic facial features, strabismus, and scoliosis are often present.
    • Prader-Willi Syndrome Mayo Clinic
      Overview Prader-Willi (PRAH-dur VIL-e) syndrome is a rare genetic disorder that results in a number of physical, mental and behavioral problems. A key feature of Prader-Willi syndrome is a constant sense of hunger that usually begins at about 2 years of age. People with Prader-Willi syndrome want to eat constantly because they never feel full (hyperphagia), and they usually have trouble controlling their weight. Many complications of Prader-Willi syndrome are due to obesity. Best managed by a team approach, various specialists can work with you to manage symptoms of this complex disorder, reduce the risk of developing complications and improve the quality of life for your loved one with Prader-Willi syndrome. Symptoms Signs and symptoms of Prader-Willi syndrome can vary among individuals.
    • Prader-Willi Syndrome GARD
      Prader-Willi syndrome (PWS) is a genetic condition that affects many parts of the body. Infants with PWS have severe hypotonia (low muscle tone), feeding difficulties, and slow growth. In later infancy or early childhood, affected children typically begin to eat excessively and become obese . Other signs and symptoms often include short stature, hypogonadism, developmental delays, cognitive impairment, and distinctive behavioral characteristics such as temper tantrums, stubbornness, and obsessive-compulsive tendencies. PWS is caused by missing or non-working genes on chromosome 15 . Most cases are not inherited and occur randomly.
    • Prader-Willi Syndrome Orphanet
      A rare genetic, neurodevelopmental syndrome characterized by hypothalamic-pituitary dysfunction with severe hypotonia and feeding deficits during the neonatal period followed by an excessive weight gain period with hyperphagia with a risk of severe obesity during childhood and adulthood, learning difficulties, deficits of social skills and behavioral problems or severe psychiatric problems. Epidemiology Prevalence at birth is estimated at 1/15,000-30,000 worldwide Clinical description The severe hypotonia at birth is associated with poor oral and social skills which remain, albeit less clinically evident, throughout life. Characteristic facial features (a narrow forehead, almond-shaped eyes, a thin upper lip and down-turned mouth), as well as very small hands and feet, are frequently observed. After this initial phase, followed by an excessive weight gain without changes in eating, the most striking signs appear: hyperphagia and absence of satiety often leading to severe obesity in affected children as young as three years of age. The situation may deteriorate quickly without strict control of food access.
    • Prader-Willi Syndrome MedlinePlus
      Prader-Willi syndrome is a complex genetic condition that affects many parts of the body. In infancy, this condition is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. Beginning in childhood, affected individuals develop an insatiable appetite, which leads to chronic overeating (hyperphagia) and obesity. Some people with Prader-Willi syndrome, particularly those with obesity, also develop type 2 diabetes (the most common form of diabetes). People with Prader-Willi syndrome typically have mild to moderate intellectual impairment and learning disabilities.
    • Prader-Willi Syndrome OMIM
      A number sign (#) is used with this entry because of evidence that Prader-Willi syndrome (PWS) is in effect a contiguous gene syndrome resulting from deletion of the paternal copies of the imprinted SNRPN gene (182279), the NDN gene (602117), and possibly other genes within the chromosome region 15q11-q13. Description Prader-Willi syndrome is characterized by diminished fetal activity, obesity, muscular hypotonia, mental retardation, short stature, hypogonadotropic hypogonadism, and small hands and feet. It can be considered to be an autosomal dominant disorder and is caused by deletion or disruption of a gene or several genes on the proximal long arm of the paternal chromosome 15 or maternal uniparental disomy 15, because the gene(s) on the maternal chromosome(s) 15 are virtually inactive through imprinting. Horsthemke and Wagstaff (2008) provided a detailed review of the mechanisms of imprinting of the Prader-Willi/Angelman syndrome (105830) region. See also the chromosome 15q11-q13 duplication syndrome (608636), which shows overlapping clinical features.
    • Schaaf-Yang Syndrome OMIM
      A number sign (#) is used with this entry because of evidence that Schaaf-Yang syndrome (SHFYNG) is caused by heterozygous mutation in the MAGEL2 gene (605283) on chromosome 15q11. Description SHFYNG syndrome is an autosomal dominant multisystem disorder characterized by delayed psychomotor development, impaired intellectual development, hypotonia, and behavioral abnormalities. Additional features include contractures, feeding difficulties, and variable dysmorphic facial features. The severity of the disorder is highly variable: some patients may die in utero with fetal akinesia, whereas others can live with moderate disability. Individuals are affected only if the mutation occurs on the paternal allele, since MAGEL2 is a maternally imprinted gene (summary by Fountain et al., 2017) Clinical Features Schaaf et al. (2013) reported 4 unrelated boys with features resembling Prader-Willi syndrome (PWS; 176270).
  • Colitis-X Wikipedia
    The probiotics most often used for this purpose contain Lactobacillus and Bifidobacterium . [2] See also [ edit ] Horse colic References [ edit ] ^ a b c d e f g h i j k "Colitis-X" . Merck Veterinary Manual . ... Retrieved 2008-11-17 . ^ Thomas C, Stevenson M, Riley TV (June 2003). "Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review" .
  • Leucism Wikipedia
    "The White King of the Forest") - documentary tv programme" . Swedish Television . ... British Birds . 111 (1): 10–24. ^ personally taken photographs ^ Ritland, Kermit; Newton, Craig; Marshall, H. Dawn (2001-09-18). "Inheritance and population structure of the white-phased "Kermode" black bear" .
  • Pinworm Infection Wikipedia
    Archived from the original on 5 November 2017. ^ a b c d e f g h i j Burkhart & burkhart 2005 , p. 838 ^ a b c d e f g h i j k l m n o p q Cook et al. 2009 , p. 1516 ^ a b c d e f g h i Gutiérrez 2005 , p. 355. ^ a b c d e f g h i j k l Caldwell 1982 , p. 307. ^ a b c d e f g h i j k l m n o Cook 1994 , p. 1159 ^ a b c d e f g h Cook 1994 , p. 1160 ^ a b c d Gutiérrez 2005 , p. 356. ^ a b Gutiérrez 2005 , p. 363. ^ Gutiérrez 2005 , p. 354. ^ a b c d e f g h i j k l m n o p q r s Burkhart & burkhart 2005 , p. 837 ^ a b c d e f g h i j k l m Garcia 1999 , p. 246 ^ Cook, G C (1994). ... PMC 1375686 . PMID 7959218 . ^ a b c d e f g h i j Caldwell 1982 , p. 308. ^ dpdx 2009 ^ Garcia 1999 , p. 247 ^ a b c d e f g h i j k l m n o p q Cook 1994 , p. 1161 ^ a b c d e Caldwell 1982 , p. 309. ^ "Fact sheets: neglected tropical diseases" . ... S2CID 21775189 . References Hasegawa H, Ikeda Y, Fujisaki A, et al. (December 2005). ... Nakano T, Okamoto M, Ikeda Y, Hasegawa H (December 2006). "Mitochondrial cytochrome c oxidase subunit 1 gene and nuclear rDNA regions of Enterobius vermicularis parasitic in captive chimpanzees with special reference to its relationship with pinworms in humans". ... Annales de Parasitologie Humaine et Comparée (in French). 58 (4): 403–4. doi : 10.1051/parasite/1983584403 . PMID 6416131 . Hasegawa H, Takao Y, Nakao M, Fukuma T, Tsuruta O, Ide K (February 1998).
    COX1, RNA18SN5
    • Pinworm Infection Mayo Clinic
      Overview Pinworm infection is the most common type of intestinal worm infection in the United States and one of the most common worldwide. Pinworms are thin and white, measuring about 1/4 to 1/2 inch (about 6 to 13 millimeters) in length. Pinworm An adult pinworm generally is 1/4 to 1/2 inch (about 6 to 13 millimeters) in length. The most common symptom of infection is anal itching, particularly at night, as worms migrate to the host's anal area to lay their eggs. While the infected person sleeps, female pinworms lay thousands of eggs in the folds of skin surrounding the anus.
  • Abortion In Croatia Wikipedia
    That was increased opposition compared to the same poll from 1999 when only 40% opposed. [15] However, this poll was criticized by some for being suggestive. [16] In 2011, Catholic bishop Valter Župan publicly called for abortion to be banned. In response, Nova TV had an opinion poll conducted, in which 67% of respondents in Croatia said they believe that the current abortion law should not be changed, while 23% supported a ban on abortions. ... Retrieved 2015-05-04 . ^ "Ekskluzivno istraživanje: Zabranu pobačaja podupiru najviše žene" (in Croatian). Nova TV . 2011-06-09 . Retrieved 2013-10-08 . ^ Vlasta Ilišin; Dejana Bouillet; Anja Gvozdanović; Dunja Potočnik (2013).
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