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  • Hiv/aids In China Wikipedia
    SIV jumped from primates to humans several times, although the primary strain of HIV responsible for the global pandemic, HIV-1 group M , is traceable to the region surrounding Kinshasha , [11] likely having initially crossed from chimpanzees around 1920. [12] From there, it spread to the Caribbean around 1967, proceeding to establish itself in New York City and San Francisco circa 1971 and 1976, respectively. [13] The Centers for Disease Control and Prevention (CDC) recognized unusual outbreaks of opportunistic infections among gay men in 1981, [14] [15] and the disease was initially referred to as Gay-related immune deficiency (GRID) , although it was quickly understood to also infect heterosexuals as well. [16] In 1982, the CDC adopted the name "acquired immune deficiency syndrome" (AIDS). [17] By the end of 1984, 7,699 cases of AIDS and 3,665 deaths had been recorded in America, with an additional cases 762 in Europe. ... Through these three systems, HIV/AIDS case reports flowed from the health facilities or clinics as follows: (1) to the local district, county, or county-level city, (2) to the prefecture or prefecture-level city, (3) to the provincial health departments, and (4) to three separate national agencies." ^ He & Detels 2005 , p. 828. ^ Kaufman & Meyers 2006 , p. 54. ^ Jia et al. 2007 , p. 1043; 1050. ^ Lin et al. 2012 , pp. 1-2. ^ Kaufman & Meyers 2006 , p. 55-57. ^ M. Wu 2006 , p. 266; 269. ^ FIDH 2005 , p. 21. ^ Wang et al. 2010 , p. ii21. ^ Steinbrook 2004 . ^ Wang et al. 2010 , p. ii24. ^ Hesketh 2007 , p. 622: "[P]redictions of the size of the epidemic were substantially overestimated by several expert bodies. ...
  • List Of Mass Hysteria Cases Wikipedia
    Ukraine authorities blamed the violence on a disinformation campaign targeting the country and spread over social media. [56] See also Body-centred countertransference Conversion disorder Folie à deux (from the French for "a madness shared by two") Hysterical contagion Psychochemical weaponry References ^ Wolf, M. (1976). Witchcraft and Mass Hysteria in Terms of Current Psychological Theories, (are caused by the use of medical/experimental delusions).
  • Listeriosis Wikipedia
    . ^ de Noordhout CM, Devleesschauwer B, Angulo FJ, Verbeke G, Haagsma J, Kirk M, Havelaar A, Speybroeck N (November 2014).
    TNF, CYLD, IL15, IFNG, HSP90B1, NOD2, SUMF2, DECR1, IL10, IL37, ISG15, STIP1, BAHD1, FAF1, ABCG2, CPQ, SIRT2, LGI1, SQSTM1, SOCS2, BECN1, PTP4A2, ARHGEF5, CARD8, ACTA1, NT5C2, CLEC5A, TP53, SENP1, NOP53, DUOX2, HSPA14, LGI2, LXN, BCL11B, CASD1, TNIP3, HAVCR2, ZNRF4, MIR146A, EIF2AK1, ADAM17, TNFRSF1A, GRIN1, IL6, IL4, IFNB1, IFIT3, HSPG2, HSPD1, GRN, ACTB, XCR1, GFAP, CCR5, CD44, CAT, CASP1, IL12A, ISG20, ITGAM, ITGB2, LIPE, MET, MYH9, NEDD4, NFATC1, OCRL, PML, PPIA, S100A1, S100B, SELE, SLC5A1, SPP1, H3P7
    • Listeria Infection Gard
      A listeria infection or listeriosis is an infection caused by a bacteria known as Listeria monocytogenes . It mainly affects newborn infants, elderly patients, pregnant women and patients who have low immunity. Listeria can be spread by several methods. A common cause is ingestion (food-borne transmission) of unpasteurized milk or contaminated vegetables. It can also be transmitted from mother to fetus during pregnancy or directly to the newborn at the time of delivery. Listeriosis can cause a variety of symptoms, depending on the person and the part of the body affected.
    • Listeriosis Orphanet
      A rare bacterial infectious disease caused by the foodborne pathogen Listeria monocytogenes , characterized by a febrile gastroenteritis, which is usually mild and self-limiting in otherwise healthy persons, but can progress to severe illness in at-risk groups like pregnant women, elderly people, immunocompromised people, and neonates. Complications include sepsis, meningitis, and encephalitis. Listeriosis during pregnancy usually occurs during the third trimester and may lead to preterm labor, miscarriage, stillbirth, or intrauterine infection of the unborn child.
    • Listeria Infection Mayo_clinic
      Overview Listeria infection is a foodborne bacterial illness that can be very serious for pregnant women, people older than 65 and people with weakened immune systems. It's most commonly caused by eating improperly processed deli meats and unpasteurized milk products. Healthy people rarely become ill from listeria infection, but the disease can be fatal to unborn babies, newborns and people with weakened immune systems. Prompt antibiotic treatment can help curb the effects of listeria infection. Listeria bacteria can survive refrigeration and even freezing. So people who are at higher risk of serious infections should avoid eating the types of food most likely to contain listeria bacteria.
  • Bulimia Nervosa Wikipedia
    PMID 23032383 . ^ a b c d e f g h i j k l m n "Bulimia nervosa fact sheet" . Office on Women's Health . ... PMID 22644309 . ^ a b c d e f g h i j k l m n Hay PJ, Claudino AM (July 2010). ... PMID 22946772 . ^ a b Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. ... PMID 26016744 . ^ Walsh BT, Roose SP, Glassman AH, Gladis M, Sadik C (1985). "Bulimia and depression" . ... Retrieved July 4, 2016 . ^ Ribasés M, Gratacòs M, Fernández-Aranda F, Bellodi L, Boni C, Anderluh M, et al.
    SLC6A4, CHODL, NKAIN3, BDNF, LEP, OPN1SW, COMT, DRD4, HTR2A, TAL1, SCLY, KRT7, GHRL, HTR2C, MC4R, MCL1, PYY, NR3C1, SLC6A3, HTR1B, BED, ADIPOQ, DRD2, GHSR, GCG, FAAH, DST, CNR1, GLP1R, DPP4, CLOCK, ZGLP1, WASF3, CIT, TBC1D9, OR4G1P, OR2AG1, MBOAT4, CTNNBIP1, GGCT, FTO, LINC00880, EHMT1, NT5C1B, SYTL5, HTR3B, ATP8A2, AGRP, PEA15, MMP9, CCND1, ESR1, ESR2, GH1, GPT, HTR1A, HTR3A, IGF1, IGF2, NTRK2, ST8SIA4, OCA2, OXTR, ALDH1A1, BRD2, SHBG, SLC2A1, SNCA, SULT1A1, TPH1, ABCB1
    • Bulimia Nervosa Mayo_clinic
      Overview Bulimia (boo-LEE-me-uh) nervosa, commonly called bulimia, is a serious, potentially life-threatening eating disorder. People with bulimia may secretly binge — eating large amounts of food with a loss of control over the eating — and then purge, trying to get rid of the extra calories in an unhealthy way. To get rid of calories and prevent weight gain, people with bulimia may use different methods. For example, you may regularly self-induce vomiting or misuse laxatives, weight-loss supplements, diuretics or enemas after bingeing. Or you may use other ways to rid yourself of calories and prevent weight gain, such as fasting, strict dieting or excessive exercise.
  • Friedreich Ataxia 1 Omim
    Left ventricular wall thickness was measured in 44 patients using M-mode echocardiography and correlated with GAA expansion size on the smaller allele (267 to 1200 repeats).
    FXN, NFE2L2, PIP5K1B, ATXN1, GABPA, DLD, EPO, CTCF, PPARGC1A, FTMT, GPAA1, ISCU, APTX, SETX, KIF1B, AHSA1, COG5, AGTR1, MFN2, PCLAF, CRTC1, TJP2, GRAP2, PDLIM1, HDAC3, AIMP2, CIR1, RNF19A, SIRT3, CHMP1B, VTRNA2-1, MIR323A, MIR155, C16orf82, CTCFL, HAMP, JPH3, SLC17A7, ATXN10, TWNK, RNF126, GLRX5, PYCARD, MLH3, POLDIP2, VIM, USP7, TP53, TYMS, TTPA, LY6E, LPA, KCNJ5, KCNC3, IFNG, IFNB1, HSPA9, HFE, GAA, ATN1, TIMM8A, CSF3, MAPK14, CRK, CD34, CASP3, CACNA1A, ATXN3, MLH1, NCF2, SPG7, APOA1, TNNT2, TNNT1, TFRC, TFPI, TEAD1, SRF, ATXN2, PDYN, S100A4, PVALB, PTGS2, MAPK1, PPP2R2B, PPARG, POLG, FTX
    • Friedreich Ataxia Gard
      Friedreich ataxia is an inherited condition that affects the nervous system and causes movement problems. People with this condition develop impaired muscle coordination (ataxia) that worsens over time. Other features include the gradual loss of strength and sensation in the arms and legs, muscle stiffness (spasticity), and impaired speech. Many individuals have a form of heart disease called hypertrophic cardiomyopathy . Some develop diabetes, impaired vision, hearing loss, or an abnormal curvature of the spine (scoliosis).
    • Friedreich Ataxia Orphanet
      Friedreich ataxia (FRDA) is an inherited neurodegenerative disorder classically characterized by progressive gait and limb ataxia, dysarthria, dysphagia, oculomotor dysfunction, loss of deep tendon reflexes, pyramidal tract signs, scoliosis, and in some, cardiomyopathy, diabetes mellitus, visual loss and defective hearing. Epidemiology The prevalence of FRDA in Caucasians is estimated at 1/20,000 to 1/50,000. Clinical description The classical presentation of FRDA begins in childhood or adolescence. General clumsiness and gait ataxia are usually the first signs to appear, often followed by pyramidal signs, upper-limb ataxia and dysarthria. Oculomotor manifestations present early and include fixation instability (square wave jerks) and nystagmus.
    • Friedreich Ataxia 2 Omim
      Description Friedreich ataxia (FRDA) is an autosomal recessive neurodegenerative disorder characterized by progressive gait and limb ataxia with associated limb muscle weakness, absent lower limb reflexes, extensor plantar responses, dysarthria, and decreased vibratory sense and proprioception. Onset is usually in the first or second decade, before the end of puberty (summary by Delatycki et al., 2000). For a general phenotypic description of Friedreich ataxia (FRDA), see FRDA1 (229300), which is caused by mutation in the FXN gene (606829) on chromosome 9q13. Clinical Features Smeyers et al. (1996) reported a nonconsanguineous Spanish family in which 2 adult sibs, a male and a female, had a phenotype consistent with Friedreich ataxia, but linkage excluded the FRDA1 locus on chromosome 9q. The patients had onset of progressive ataxia at ages 10 and 14 years, respectively.
    • Friedreich Ataxia Medlineplus
      Friedreich ataxia is a genetic condition that affects the nervous system and causes movement problems. People with this condition develop impaired muscle coordination (ataxia) that worsens over time. Other features of this condition include the gradual loss of strength and sensation in the arms and legs; muscle stiffness (spasticity); and impaired speech, hearing, and vision. Individuals with Friedreich ataxia often have a form of heart disease called hypertrophic cardiomyopathy, which enlarges and weakens the heart muscle and can be life-threatening. Some affected individuals develop diabetes or an abnormal curvature of the spine (scoliosis ).
    • Friedreich Ataxia Gene_reviews
      Nerve conduction studies generally show a motor nerve conduction velocity of greater than 40 m/s with reduced or absent sensory nerve action potential with an absent H reflex.
  • Exhibitionism Wikipedia
    Retrieved 2012-08-01 . ^ Hirschfeld, M. (1938). Sexual anomalies and perversions: Physical and psychological development, diagnosis and treatment (new and revised ed.).
    FLNB, USO1, NXF1, SEC14L2
  • Alcohol And Health Wikipedia
    Among women, light drinkers have a four percent increased risk of breast cancer, while moderate drinkers have a 23 percent increased risk of the disease. ^ a b Noelle K. LoConte, Abenaa M. Brewster, Judith S. Kaur, Janette K. ... Page 228. ^ helsinki.fi – Effect of alcohol on hormones in women Archived 11 August 2017 at the Wayback Machine , Helsinki 2001 ^ helsinki.fi – Clinical studies on dependence and drug effects Archived 21 February 2013 at the Wayback Machine , ESBRA 2009 ^ Horowitz M, Maddox A, Bochner M, et al. (1989). ... Retrieved 29 August 2015 . ^ Feige B, Scaal S, Hornyak M, Gann H, Riemann D (2007). "Sleep electroencephalographic spectral power after withdrawal from alcohol in alcohol-dependent patients". ... ISBN 9781483374383 . ^ Grattan, Karen E.; Vogel-Sprott, M. (2001). "Maintaining Intentional Control of Behavior Under Alcohol". ... S2CID 5859834 . ^ Brockie, TN; Heinzelmann, M; Gill, J (2013). "A Framework to Examine the Role of Epigenetics in Health Disparities among Native Americans" .
    ALDH2, AVPR1B, SLC29A1, GGT1, ADH1B, NCALD, PECR, PLGRKT, FSTL5, ANKS1B, PKNOX2, LHPP, SLC39A8, FTO, CSRNP3, IGSF22, AGBL4, C15orf32, RHBDL2, SERINC2, CCSER1, STX18-AS1, LINC02268, LINC01818, LINC02661, AOX3P, MREG, C16orf72, ARL15, NRXN1, ADH4, CTNNA2, ESRRG, GCKR, GRK5, KCNJ6, MICB, ADH1C, BRAP, MBNL2, SEMA3A, STAG3, KLF12, IGSF9B, PPP1R16B, FAM162A, UTP20, AOX3P-AOX2P, GSTM2, GSTM1
  • Costello Syndrome Gene_reviews
    Early examples of Costello syndrome were reported as: AMICABLE syndrome ( a micable personality, m ental retardation, i mpaired swallowing, c ardiomyopathy, a ortic defects, b ulk, l arge lips and lobules, e ctodermal defects) [Hall et al 1990]; Faciocutaneous-skeletal syndrome [Borochowitz et al 1992].
    HRAS, KRAS, PTPN11, MAP2K1, BRAF, MAP2K2, RAF1, SHOC2, RASA1, SOS1, RIT1, RASA2, PPP1CB, SOS2, RRAS, NRAS, LZTR1, MRAS, A2ML1, ELN, MAP2K7, TP53, TBCC, STATH, RGS6, PLK4, SNAI2, ZHX2, SGSM3, CHST11, IL23A, AKT1, REG1A, MAPK1, CDK4, CDKN2A, CDKN2D, VCAN, EGF, EPHB2, F9, GLB1, IGF2, PDGFB, PDGFRB, PIK3CA, PIK3CB, PIK3CD, PIK3CG, H3P13
    • Costello Syndrome Omim
      A number sign (#) is used with this entry because of evidence that Costello syndrome (CSTLO) is caused by heterozygous mutation in the HRAS gene (190020) on chromosome 11p15. A variant of Costello syndrome, congenital myopathy with excess of muscle spindles, is also caused by mutation in HRAS. Costello syndrome shows phenotypic overlap with cardiofaciocutaneous syndrome (CFC; 115150) and Noonan syndrome (see 163950). Description Costello syndrome is a rare multiple congenital anomaly syndrome associated in all cases with a characteristic coarse facies, short stature, distinctive hand posture and appearance, severe feeding difficulty, and failure to thrive. Other features include cardiac anomalies and developmental disability.
    • Costello Syndrome Orphanet
      A rare syndrome with intellectual disability, characterized by failure to thrive, short stature, joint laxity, soft skin, and distinctive facial features. Cardiac and neurological involvement is common and there is an increased lifetime risk of certain tumors. Costello syndrome belongs to the RASopathies, a group of conditions resulting from germline derived point mutations affecting the RAS-mitogen activated protein kinase pathway. Epidemiology Costello syndrome (CS) estimated number of patients worldwide is 300. Estimated birth prevalence has been reported to be 1/300,000 to 1/1 250 000.
    • Costello Syndrome Medlineplus
      Costello syndrome is a disorder that affects many parts of the body. This condition is characterized by delayed development and intellectual disability, loose folds of skin (which are especially noticeable on the hands and feet), unusually flexible joints, and distinctive facial features including a large mouth with full lips. Heart problems are common, including an abnormal heartbeat (arrhythmia), structural heart defects, and a type of heart disease that enlarges and weakens the heart muscle (hypertrophic cardiomyopathy). Infants with Costello syndrome may be larger than average at birth, but most have difficulty feeding and grow more slowly than other children. People with this condition have relatively short stature and may have reduced growth hormone levels. Other signs and symptoms of Costello syndrome can include tight Achilles tendons (which connect the calf muscles to the heel), weak muscle tone (hypotonia), a structural abnormality of the brain called a Chiari I malformation, skeletal abnormalities, dental problems, and problems with vision.
    • Costello Syndrome Gard
      Costello syndrome is a rare condition that affects many different parts of the body. Signs and symptoms generally include developmental delay, intellectual disability, distinctive facial features, loose folds of extra skin (especially on the hands and feet), and unusually flexible joints. Affected people may also have heart abnormalities such as tachycardia , structural heart defects, and hypertrophic cardiomyopathy . Beginning in early childhood, people with Costello syndrome additionally have an increased risk to develop certain cancerous and noncancerous tumors. Costello syndrome is caused by changes (mutations) in the HRAS gene. It is considered an autosomal dominant condition, but almost all cases are the result of de novo gene mutations and occur in people with no family history of the condition.
  • Peripheral Artery Disease Wikipedia
    Archived from the original on March 31, 2017. ^ a b c Bedenis, R; Stewart, M; Cleanthis, M; Robless, P; Mikhailidis, DP; Stansby, G (October 31, 2014). ... S2CID 8026674 . ^ a b Norgren, L.; Hiatt, W. R.; Dormandy, J. A.; Nehler, M. R.; Harris, K. A.; Fowkes, F. G. ... Dennis; Ernst, Calvin; Johnston, K. Wayne; Porter, John M.; Ahn, Sam; Jones, Darrell N. (September 1997). ... PMID 24126108 . ^ US Preventive Services Task, Force.; Curry, SJ; Krist, AH; Owens, DK; Barry, MJ; Caughey, AB; Davidson, KW; Doubeni, CA; Epling JW, Jr; Kemper, AR; Kubik, M; Landefeld, CS; Mangione, CM; Silverstein, M; Simon, MA; Tseng, CW; Wong, JB (July 10, 2018). ... S2CID 18384741 . ^ Chowdhury, Mohammed M.; McLain, Alexander D.; Twine, Christopher P.
    BMP8A, BMP2, LPA, ABO, F5, LPL, TCF7L2, OSBPL10, TNIK, MACF1, COL4A1, CNNM1, PADI4, MTHFD1L, HDAC9, WWOX, CRP, TRAM2, ZYG11B, FEZ1, MMP3, NDUFB9, VEGFA, UTRN, UGDH, CNOT4, CNTN3, CELSR2, VIT, ATXN2, PPP2R2C, DHX40, PTPN11, LRRTM4, RILPL2, PKN2-AS1, UGDH-AS1, CDKN2B-AS1, PPIEL, PDYN-AS1, HGF, UBAC2, GOT1, NSMCE1, IL6, RBFOX1, SYTL3, PPP4R2, TLR10, PAQR8, TRIM5, CREB3L1, EFHC1, OPN4, ACE, PCSK9, ALB, APOB, MTHFR, TNF, P2RY12, THBS1, CCL2, ARSA, IL1B, F2, HIF1A, TNFRSF11B, NOS3, FABP4, HMGB1, MMP2, LGALS3, ADIPOQ, CST3, SELENBP1, ADA, AHSG, APOE, RETN, CCHCR1, HMOX1, SHBG, STAT3, TLR4, PON1, MIR93, SELENOP, COPD, CXCL8, JAK2, KNG1, PTCRA, LIPC, PCYT1A, SLC5A2, S100A9, GDF15, FURIN, PLA2G7, BEST1, PTX3, CERNA3, AVP, FGF2, EDN1, CHI3L1, GCH1, CDKN1A, F11, ANGPT2, AGTR1, AGER, F2R, F10, DPP4, B2M, SGSM3, EIF3K, SETD2, PADI1, IL22, SDF4, IL1A, BFAR, CETN1, FXYD5, UGT1A1, AGGF1, ADI1, CHDH, ZNF415, ACSS2, ANGPTL8, CEBPA, CHRNA3, FGF21, PPARGC1A, CSF2, CS, ZEB2, NR1H4, CASP8AP2, SH2B3, ABCB6, IL18BP, PSMD14, FBLN5, TCFL5, ADAMTS13, SOSTDC1, ADAMTS5, ADAMTS7, PADI2, NLRP1, COX8A, TRS-AGA2-3, ANGPTL2, MAP3K8, CHRNB4, PLA2G15, FAM20C, SCARB1, SLC52A2, RTN4, MIR125A, ARG2, ABCC6, AR, TET3, PRSS55, APOH, APOA1, ANGPT1, MIRLET7G, MIR106B, MIR140, CSMD1, MIR15B, MIR18A, MIR29A, AGT, ACOD1, ADRB2, HLP, ADD1, ACR, CBSL, ALDH7A1, PWAR1, LRG1, NUS1, CD36, TBPL1, CD34, CD14, CBS, PPP1R2C, SLC2A10, CASR, ANGPTL6, SPRTN, ANTXR1, ZGPAT, SPZ1, TRIM63, ACCS, CAD, BLM, BCL2, CCND1, CARD16, ATP7B, CSF3, IL1RL1, CSTB, CX3CR1, NFE2L2, FOXO1, FGG, NPY, NPPB, NPPC, NPR3, NT5E, NUCB2, FGF1, FGB, SERPINA5, FAP, ENPP1, PECAM1, F13A1, ABCB1, PLG, PODXL, F12, PON3, MAPK1, EIF2AK2, FLNA, MYB, MTTP, LEP, SERPIND1, HARS1, IL10, IL18, GPX4, KDR, GNB3, IPO5, LAMP2, LDLR, GIP, FLT1, GABPA, FSHMD1A, MCAM, MFAP4, FOS, FN1, MMP9, MMP13, MPO, MT1B, PTGS1, PTGS2, F8, CYBB, TNFRSF1A, TNFRSF1B, TP53, CRISP2, DAPK3, CYP2C19, VCAM1, CYP2B6, CYP1A2, WRN, CUBN, TLR2, BRAP, YBX3, PRKRA, TNFSF11, NR1I2, TRPA1, CYBA, HGS, IFNG, ADGRG1, DECR1, THBS4, RAP2A, SFTPD, RBBP6, REN, SORT1, F3, SAA1, EPHB2, CXCL12, SELP, ENG, SRSF5, MARK2, ATN1, SHH, EDNRA, SLC25A1, SRD5A1, SRD5A2, SULT1E1, TAC1, DUSP5, TEK, TERF2, NAT2
  • Childhood Obesity Wikipedia
    Retrieved 15 December 2013 . ^ Javed, A.; Jumean, M.; Murad, M. H.; Okorodudu, D.; Kumar, S.; Somers, V. ... PMC 3073855 . PMID 20451244 . ^ Seipel, M. M.; Shafer, K (2013). "The effect of prenatal and postnatal care on childhood obesity". ... CS1 maint: multiple names: authors list ( link ) ^ Wolfenden L, Barnes C, Jones J, Finch M, Wyse RJ, Kingsland M, Tzelepis M, Grady A, Hodder RK, Booth D, Yoong SL (10 February 2020). ... Retrieved 2013-02-04 . ^ French SA, Story M, Neumark-Sztainer D, Fulkerson JA, Hannan P (2001). ... PMID 17111891 . ^ Reinehr T, Wabitsch M (2011). "Childhood Obesity". Current Opinion in Lipidology . 22 (1): 21–25. doi : 10.1097/MOL.0b013e32833f9c37 .
    FTO, APOA1, CETP, APOA5, ADIPOQ, LEP, MC4R, MC3R, POMC, PPARG, LEPR, INS, FABP4, DRD2, ENPP1, ALMS1, PPARA, NMU, GPT, BDNF, APOE, ANGPTL4, ADRB3, GCG, SIRT1, FAAH, OLFM4, GNB3, IL17A, IL10, IGF1, HP, MMP9, GRN, BCL2, RBP4, TMEM18, CNR2, PON1, UCP2, UCP3, CAT, AMD1, PNPLA3, VEGFA, TST, HCP5, UCP1, SOD2, STAT3, EBP, TGFB1, SLC6A8, SLC6A4, TNF, MKKS, CTPP, RAMP2, NAMPT, HDAC4, GDF15, LRAT, ARHGEF2, SOCS3, WASF1, PER3, PDE8B, NR0B2, ACACB, RRAS2, GNPDA2, MBOAT7, STEAP4, TMEM134, LIMD2, ARID5B, MCHR2, LINC00839, NMS, SKA1, NEDD4L, GPX6, ENHO, MIR17, MIR216A, MIR27A, MIR412, RAMP2-AS1, MIR1203, KCTD15, AKTIP, HIF3A, TNMD, SH2B1, FGF21, MYCBP, FETUB, ACAD8, SFRP5, IL22, SOST, TNNI3K, ZNF771, KLF13, NLK, GHRL, TM6SF2, LRP1B, MAGEL2, RETN, SCG5, PLIN1, SCD, FDXR, CNR1, CORD1, CRP, DNMT1, DRD4, ELAVL2, FAT1, GAD2, CD69, GC, GCKR, GH1, GHR, GHSR, GIPR, GPX1, CNP, CD5L, GPX5, AQP7, ADCY3, ALB, AKR1B1, AMY1A, AMY1B, AMY1C, ANGPT1, ARSD, CALR, ATP5F1E, BBS2, BBS4, BCKDHB, BNIP3, DST, CALCR, GPX4, GYS2, SAA1, PMAIP1, OXTR, SERPINE1, PCK1, PCSK1, PEX1, PGF, ADA, MAP2K5, NUCB2, PYY, PTH, PTPRN2, PTPRS, SNORA73A, RORC, SORT1, TNFRSF11B, NPY2R, HFE, LMNA, HSD11B1, IGF2, IMPDH2, IRS1, ITIH4, KCNC2, LGALS1, LMX1B, NOS3, LPL, MEST, MMP2, MSRA, ATP6, CYTB, MTNR1B, MIR642B
    • Childhood Obesity Mayo_clinic
      Overview Childhood obesity is a serious medical condition that affects children and adolescents. It's particularly troubling because the extra pounds often start children on the path to health problems that were once considered adult problems — diabetes, high blood pressure and high cholesterol. Childhood obesity can also lead to poor self-esteem and depression. One of the best strategies to reduce childhood obesity is to improve the eating and exercise habits of your entire family. Treating and preventing childhood obesity helps protect your child's health now and in the future. Symptoms Not all children carrying extra pounds are overweight. Some children have larger than average body frames.
  • Leukemia Wikipedia
    Archived from the original on 11 February 2009. ^ Valbuena JR, Herling M, Admirand JH, Padula A, Jones D, Medeiros LJ (March 2005). ... Archived from the original on 10 September 2017. ^ Radivoyevitch, T; Sachs, R K; Gale, R P; Molenaar, R J; Brenner, D J; Hill, B T; Kalaycio, M E; Carraway, H E; Mukherjee, S (2015). ... Retrieved 4 September 2007 . ^ Eichhorst BF; Busch R; Hopfinger G; Pasold R; Hensel M; Steinbrecher C; Siehl S; Jäger U; Bergmann M; Stilgenbauer S; Schweighofer C; Wendtner CM; Döhner H; Brittinger G; Emmerich B; Hallek M; German CLL Study Group. (2006). ... Retrieved 18 May 2008 . ^ Robak, T; Jamroziak, K; Gora-Tybor, J; Blonski, J. Z.; Kasznicki, M; Dwilewicz-Trojaczek, J; Wiater, E; Zdunczyk, A; Dybowicz, J; Dmoszynska, A; Wojtaszko, M; Zdziarska, B; Calbecka, M; Kostyra, A; Hellmann, A; Lewandowski, K; Stella-Holowiecka, B; Sulek, K; Gawronski, K; Skotnicki, A. ... PMID 21239766 . ^ Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De León FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, Memish ZA (December 2012).
    ATM, FANCD2, FANCC, BLM, FANCA, FANCG, FANCE, FANCF, NRAS, BRIP1, BRAF, ERG, TNFSF10, PTEN, STAT3, PTPN11, CDKN2A, PRAME, JAK2, KMT2A, WT1, GSTM1, CSF3R, MSH6, IL2, CCND1, SETD2, ESR1, TOP2A, LIG4, PLK1, HP, NF1, CFLAR, FOXM1, MGMT, KMT2E, PRF1, DDIT4, AR, BIRC2, FGF1, SMPD3, STAG2, BAD, PPP1R13L, LINC00977, PRKCZ, AQP9, GSTO1, NCOA3, BIRC3, SPHK1, SYNCRIP, BAP1, CREBBP, KRAS, MLH1, PIK3CA, BRD4, GATA2, TERT, MSH2, EP300, RB1, MYD88, CFTR, NUTM1, HAX1, KDM1A, CASR, RAF1, CD6, CBFB, FLT3, GEM, CXADRP1, STAT5A, STAT5B, PRMT5, TBC1D9, RUNX1, RUNX1T1, LONP1, MTOR, GATA1, RARA, NOTCH1, MECOM, FANCB, CTRC, SNAP91, ATN1, NR1I3, DNMT3A, CDKN1A, CDKN1B, DNMT1, CDKN2B, NQO1, IKZF1, MIR155, SCN11A, CXADR, CEBPA, CTNNB1, CEBPZ, CSF3, CSF2, SCN10A, SCN9A, CD19, TET2, MS4A1, CD22, EZH2, TCL1B, EVPL, CD33, CD34, ETV6, CD38, KRT20, VEGFA, CD40LG, CD44, ETS1, SPINK1, SPG7, EPO, EIF4E, CASP3, PRSS1, HIF1A, KIR3DL1, MEIS1, MDM2, ANPEP, MCL1, MLLT10, ABCB1, ASRGL1, APC, KAT6A, PIK3CB, LMO2, PIM1, PIK3CD, PIK3CG, HRX, POT1, KIF11, TERC, HLA-A, MEN1, PBX1, PAX5, PICALM, ABL1, NPM1, TNF, NUP98, NCAM1, MYH11, MYC, MYB, MTTP, TP53, PARP1, MTHFR, TCL1A, ABCC1, AKT1, MPO, MME, MLLT1, KIT, ARR3, CCR7, MAPK1, BCR, PRKAR1A, BMI1, DOT1L, TCF3, ALL1, TAL1, TMEM132D, MBD2, TLX1, BRCA2, HOXA@, TRIM13, CCNA1, HOXA10, BUB1B, IDH1, CALM1, CALM2, IDH2, PML, COMMD3-BMI1, PMS2, IL15, CXCR4, IL6, IL3, HOXA9, TRBV20OR9-2, IGH, BCL2, CALM3, IFNA13, IFNA1, NFE2L2, HLA-B, KDR, DNER, MAPK8, MLLT3, CXCL12, FHIT, ASPG, KLRK1, IFNG, IL1B, PROM1, ERVW-1, SPI1, OPN1SW, CD274, KLRC4-KLRK1, H3P10, CDK2, BTK, BRCA1, BAX, FUT4, FAS, FGFR1, PRAM1, MAPK14, MPL, MDM4, CBFA2T3, IRF8, CYP1A1, ELANE, NUP214, MIR21, ABO, GSTT1, JAK3, PTPA, DEK, RAC1, HPGDS, PRDM16, HLA-DPB1, TRIB2, ZBTB16, G6PD, PBX3, BCL11A, SCLY, PCBP4, PAG1, XIAP, TRIM5, HLA-C, IL2RA, SUB1, DHFR, WLS, LEP, AFF1, LIF, ABCG2, HSP90AA1, ZAP70, MAP2K7, NXT1, MRPL28, NBN, KRT7, IL10, SOAT1, FN1, H3P9, TOP1, ERVK-20, HDAC9, XRCC1, MARCKSL1, TPMT, IL7, FLI1, OPN1LW, EWSR1, SRC, IRF1, NCOA2, SCT, GFI1, CDK4, RAG2, RUNX2, HLF, PRTN3, CD80, IL2RG, CD14, S100A4, IL7R, AHI1, GSTK1, FASLG, APRT, MIR150, AFDN, BCL6, NME1, CCR5, NM, NFKB1, SLCO6A1, MAPK3, MIR17HG, MAP2K1, TLX3, MSH3, FLT1, FLII, PPARG, TGFB1, CD47, CIB1, LEF1, CDK6, MSI2, CNTNAP1, DNMT3B, LMO1, MNX1, APEX1, TET1, PDGFRA, SALL4, CD27, HPRT1, GABPA, HRAS, ASXL1, ZNF384, IL24, FLT3LG, IGF1, ICAM1, F2R, FGF2, DLL1, FUT1, AHSA1, RNASE3, HMGB1, GLIS2, PSIP1, POLDIP2, DCC, NR0B2, FBXW7, MFAP1, CD99, RTEL1, NR3C1, ALDH1A1, MIR22, FTO, SLC9A1, MMP9, PTPN6, THY1, MIR29B1, MIR29B2, PTPRC, SEPTIN9, GSTP1, CRK, MIR196B, CREB1, ROR1, CRLF2, PIM3, ABL2, SET, PECAM1, AIMP2, EGFR, ITGAM, HMOX1, EPOR, PHF6, EPHB2, SLC12A9, TP73, ASNS, CDK1, RNF19A, CALR, SAI1, MERTK, GRAP2, ZNF521, DOK1, MIR126, PDIK1L, LGALS3, EBF1, HLA-G, TAT, TRIB1, SIRT1, BUB1, TAC1, PSMB6, HOXA5, ADAM17, YY1, HFE, HOTAIR, HEMGN, TPPP2, JAK1, HTC2, ANXA2, MAFK, FIP1L1, H3P12, ERVK-18, BIRC5, APAF1, ABCB4, LYZ, PDGFRB, MEF2C, LBR, MLF1, MMP2, CD200, ERVK-32, MUC1, ACTB, CDR3, ACHE, TLR4, SOCS1, STMN1, BMP4, IL4, TSLP, IFI27, PDLIM5, BCL2A1, BCHE, INPP4B, IL1A, POU5F1, IL3RA, IL6ST, LETMD1, CXCL8, AXL, IL18, ILK, ATR, IRF4, ITGB2, QRSL1, IGF2BP1, ARHGEF1, CHEK2, CD40, DDX41, CBL, ZEB2, EGR1, WWOX, RUNX3, LRPPRC, CDKN2C, GLB1, MIR223, ZHX2, S100A8, CDA, RAG1, DCDC2, CDX2, ATXN1, TYMS, NAT2, EEF1E1, TYR, MACROD1, REN, RARG, SRSF2, MVP, DAXX, ATRAID, LAMTOR1, AURKA, MIR16-1, VAV1, CFL1, FCER2, F3, GRB2, WDR5, POU5F1P3, PDCD5, POU5F1P4, SYK, UBE2I, COL11A2, VDR, GSK3B, CRKL, ZNF197, CRYZ, SH2B3, PTK2B, CSF1R, RAC2, GPT, RAD51, APP, CCL2, DPY30, KMT2B, CCL3, EPS15, TCHP, KCNH2, LMNA, CDKN1C, SBDS, COL18A1, ABI1, SELL, AKR1C3, LINC01194, GYPE, E2F1, KLK3, TEK, CD79A, RERE, TNFSF13, POGLUT1, PIN1, TICAM2, ERCC2, ITGB3, CIAPIN1, SP100, ARHGAP24, EPHA3, GYPB, RALBP1, KMT2C, NAMPT, EBI3, TAF15, SOD1, CES1, OSM, SLC22A1, GORASP1, H3P23, MYCN, UGCG, SMARCA1, HMGA2, NCL, DCLRE1C, ELL, SMARCA4, COX8A, ERVK-6, NTRK1, NGFR, GDE1, CHEK1, PRG4, AHR, TNFSF13B, TLR9, FOXP3, NR4A3, SMAD4, DECR1, GADD45A, SETBP1, ACE, DCK, SPP1, TMED7, SLC52A2, PCNA, AICDA, CCN2, TFRC, THBS1, CYBB, DCTN6, ALK, AKR1B1, CTSG, KMT2D, THPO, MOS, WNK1, KDM6A, FGFR3, REG1A, BCL2L1, TMED7-TICAM2, CDKN2B-AS1, KLF4, WT1-AS, FPGS, SOCS3, NR4A1, ATG5, FLT4, HMMR, RGPD2, SF3B1, FOXO3, ID1, HOXB3, RELA, TCF7, JMJD1C, NOTCH3, CCNA2, DLEU2, HSPA5, GATA3, HOXB4, WNT5A, BCL10, CNTN2, BSG, EIF2AK2, ZNRD2, TCF4, PIM2, HSF1, NLRP2, HOXD13, KAT2A, AGFG2, PSMD9, HES1, NR1I2, XRCC3, FDXR, CLEC12A, GYPA, PVT1, CD28, B2M, EMB, OSCP1, HDAC1, NT5C2, PTPN2, SYT1, CD9, IL18R1, HIC1, ASH2L, DICER1, CD5, ROCK1, NUDT15, AURKB, GZMB, H4-16, AFF4, FCGR3B, PWAR1, RBPJ, FCGR3A, TNFRSF10B, ROS1, SON, SIRT6, PRKN, PSMA7, HSP90B2P, MRTFA, CD244, PAK3, SNAP25, IL23A, TWIST1, SMPD2, BACH2, A1CF, XIST, PTPRO, ABCC8, XPO1, RAD52, POLD4, PTK7, ZBTB7A, ODC1, PTGS2, TSG101, KLF10, CIP2A, PAEP, RANGAP1, PAFAH1B1, NECTIN2, TLR2, RAP1GAP, PVR, TIMP2, PTPN4, USP7, ATF7IP, PAX3, TRD, TRDD3, S100B, DDX4, PKM, TRBC1, TERF1, ACKR3, S100A9, TRDC, PRDM2, RNF6, SRPK2, SRPK1, PLAGL2, PLAT, TRDJ1, SRI, B3GAT1, TPM3, RXRA, PLAU, RPS19, LEPQTL1, EXOSC5, DLL4, SPIB, METTL3, POLE4, POLD1, ST8SIA4, PIP4K2A, BCOR, STIL, PF4, TGFBI, HIPK2, KDM3B, SH3GL1, PDC, ENOSF1, THUMPD1, IGHV1-12, PDCD1, PDGFB, U2AF1, SPN, WEE1, HNF1A, MAPK7, RET, SELP, PHB, NSD3, TF, TFPI2, SELE, VCAM1, KDM5A, ZFP36, SOX4, TYRO3, SDC1, ETV7, STAT1, TEAD1, KDM5B, GNL3, CSF1, HERPUD1, ABCB5, SETD1A, SLC29A1, ENG, EMD, EIF4A2, EIF4A1, EGR3, ANKRD26, LIN28B, TELO2, DUSP1, MIR125A, DNTT, DNASE1, MIR143, MIR15A, DAPK1, MIR183, MIR193A, CYP3A5, MIR203A, CYP2D6, CYP2B6, CYP1B1, CUX1, CTSB, MIR221, ESPL1, PLA2R1, DKK1, SEPTIN6, HGF, HDC, HDAC2, CCNE2, H2AX, GSN, GRIA3, GPX3, XPR1, PLB1, BTLA, CREBRF, GH1, ADIPOQ, F9, RECQL4, GPR180, NR5A2, KDM6B, NCR1, NOS2, FOXC1, KDM4C, FH, FGF4, FES, BCAR1, ASPM, CTNNA1, MIR34A, HMBS, MIR34B, CASP9, CASP8, CASP2, MAGED4, CALCA, C3, BTG1, BST2, DUX4, ARL6IP5, BCL3, BCAT1, ATRX, RAB40B, ASPA, ASIP, ABCC6, AQP8, ANG, ALPP, ALPI, ALOX5, ALB, EBP, ADAR, H3P13, ACP3, H3P5, ACACA, CAV1, MIR638, CCNB1, CDC42, CNTF, CCR6, OLIG2, GPHN, ABCC4, CEBPB, MIR375, CD52, CDKN2D, CDK9, DLEU1, H4C15, CDH1, CD70, CCNE1, MIR486-1, CD59, CD48, BCRP3, CD36, TNFRSF8, CD8B, CD8A, SCFV, CD3G, CD1D, CD1C, CD1A, GPRC5A, FOS, HSPB1, ABCC11, ISG20, INPP5D, KDM2B, MEF2D, MEIS2, CXCL10, IL17A, ZNF268, H4C5, TNFRSF9, H4C2, IL11, H4C8, TNFRSF10A, HAVCR2, IL5, IL1RN, H4C3, IL1R1, NUDCD1, ZC3H12A, SH3BP4, NRP1, H4C11, H4C12, ITGA2B, MECP2, H4C13, RPSA, LTA, GAS7, ULBP2, SMAD2, SAMHD1, MAGED4B, LIFR, LGALS1, LEPR, LDLR, LCK, BECN1, CD46, LAIR1, ABCC3, BAALC, RIPK1, MAGEA1, ROPN1L, MAGT1, TNFSF9, HMGA1, H4C14, ITGAL, SOCS2, IGFBP7, IFNAR1, NOD2, RBM15, IER3, HOXC5, HOXC4, HOXB7, MYOD1, ATG3, H4C9, HOXB@, CLDN5, HOXA11, HOXA7, HOXA4, HSPB3, NGF, HOXA1, CHAF1B, NOS1, MTRR, HOXC6, HTN3, GFI1B, H4C6, MRC1, IAPP, H4C4, H4C1, LYL1, HSPB2, LATS2, SERINC3, TRPM5, RUVBL2, ESM1, TFPT, HPSE, CCR9, COPS5, MYCBP, CHIC2, MTHFD2, NUDT21, HSPB8, SENP1, ZNF451, PHGDH, CHD5, ABHD2, MLLT11, EHMT2, CNTRL, APOBEC2, RIPK3, TES, PSAT1, BLNK, UHRF1, PAPOLA, FBXO9, TPPP, ADRM1, MRPS30, EPC2, RNU1-1, CKAP2, MAPRE2, TMED2, HEY1, L3MBTL1, MKRN2, RBFOX2, PHF8, LPAR3, PADI4, ZNF423, TRIM35, MYCBP2, SGSM3, SSBP2, NUP62, SETD1B, SETX, DESI1, CEP152, FAM168A, IGHV3-69-1, TRIM32, IGHV3OR16-7, CBX7, TNFRSF13B, KCNH3, FRAT2, POLM, ARHGEF12, SMCHD1, MLC1, SYNE1, FBXW11, KAT6B, WWC1, COBL, TNPO3, APOBEC3C, TRBV16, KAT7, QPCT, LAMP5, ZC3H7A, SIGLEC7, NOX1, DNAJC2, TFIP11, DROSHA, SNF8, PACSIN2, AKAP13, PYCARD, WIF1, IBTK, CORO1A, RGCC, FLVCR1, TRBV7-9, HSPA4L, SIRT2, SMPX, SIGLEC9, SACM1L, INVS, CILK1, LAT, PARK7, IKZF3, TUSC2, PDAP1, SGK3, PHB2, ECD, CHP1, NAT1, KCNIP3, SPINK6, SERINC5, ZBTB38, IL27, GPRC6A, APOBEC3A, CRTC2, ARID2, CLEC4C, DDX53, RASSF6, OXER1, LEXM, ZNF296, SPRED1, SLC5A8, SLC35G1, NKX2-3, NCR3, MRGPRX1, COPD, GOLGA6A, SERP2, MALAT1, GJB7, PWAR4, ARSH, CXorf66, C16orf96, STING1, CSNK2A3, CLEC4D, P2RY8, FRYL, VSTM1, PGP, HECTD4, NEAT1, CBLL2, VPS13B, ESCO2, MIR155HG, MRGPRX3, ARAP1, MRGPRF, CMTM5, LRRC3B, UHRF2, CGAS, DTX2, TWIST2, SLC46A1, IL17F, PRRT2, ZNF300, SLFN11, ESAM, LRSAM1, MRGPRX4, LRRK2, NKAIN2, BRI3BP, MARVELD2, PPM1K, PAQR3, LYPD4, APCDD1, A2ML1, NRSN1, GATA5, B4GALNT2, S100A16, PACRG, GPR151, CD200R1, RBM45, UHMK1, XRCC6P3, LOC390714, MIR107, ZNRD1, MIR10A, ERVK-2, BCL2L2-PABPN1, DEL11P13, TMX2-CTNND1, MICA, OCLN, HOTAIRM1, LINC01672, CD24, VIM2P, BMI1P1, CEMP1, CCR2, SPANXB1, POTEF, ANXA8L1, SSX2B, MIR4739, ERVK-12, ERVK-22, LOC102724971, H3P19, H3P47, LINC02605, LOC110806263, LOC105379528, LUNAR1, BGLT3, U2AF1L5, PARTICL, CBSL, LOC102724334, GATD3B, LOC102723407, LINC01152, AK6, ERVK-11, MIR663A, MIR600, MIR563, MIR146A, MIR29A, MIR27A, MIR23A, MIR222, MIR182, MIR17, MIR149, MIR144, MIR93, MIR142, MIR130A, MIR128-2, MIR128-1, MIR127, MIR125B2, MIR122, MIR29C, MIR98, ANXA8, MIR378A, UCA1, LINC00273, RASSF10, MIR495, MIR146B, MIR511, MIR449A, RBMXL1, EIF2AK4, TARP, MIR345, MIR331, GPR166P, ZFAS1, VN1R17P, NRARP, MLIP, GADD45GIP1, SLC25A21, SIGLEC10, DDX43, TRPV6, MEG3, LARP6, PI4K2B, ASXL2, PACC1, TRIM62, RCBTB1, MTPAP, FANCL, TESC, ANKHD1, WBP1L, SWT1, TRPM7, FBLIM1, SOX6, ZFP64, CNDP2, KYAT3, PMEPA1, LXN, ANKS1B, GPR137, RETN, LTB4R2, TRPV5, RNF20, SEPTIN11, MYDGF, WSB2, PBK, ASH1L, BEX1, DHX32, TMEM30A, PDP1, UGT1A1, EGLN1, DCTN4, UBR5, KLRF1, DACT1, TNFRSF12A, GMPR2, TLR7, HERC5, EGFL7, TRPV2, KMT5B, MLXIPL, GAL, ASAP1, MBL3P, IL22, NOX4, WNT16, CHMP5, ROBO4, MAP3K20, WNT4, H2BS1, A4GALT, S1PR5, MBD3, IL17D, ADA2, ATP8A2, NCKIPSD, ARID4B, CMPK1, GINS2, PIAS4, MED15, HDAC7, SIRT7, SMYD2, KNL1, TIGAR, TSGA10, JAM3, DYNLRB2, SOX7, TCF7L1, AMN, CAB39L, DUSP16, ULBP1, FSD1L, TRABD, SCD5, NANOG, UBA5, EHMT1, LIN28A, SUV39H2, CRISPLD2, USP42, VTCN1, ZFYVE19, LMLN, WNT3A, SLC22A16, EAF1, REPS1, UBL7, MIR22HG, ZNF382, KAT8, C19orf48, CBX2, BEX2, NT5C1A, RHOXF2, ZDHHC16, ARID5B, CCDC51, PGBD5, ZNF695, STIM2, LGR6, SIGIRR, ACE2, IL21, PLEKHB1, TRIB3, METTL14, PCDH10, BCORL1, AHRR, SCYL1, VANGL2, MCOLN1, ZMIZ1, RALGAPB, GOPC, NYX, PRDM14, MUL1, INTS3, NOX5, FSD1, TNIP2, PHF23, PVRIG, CENPM, GGCT, RTN4R, MAGEF1, ACD, BCL11B, CDCP1, MARCHF7, SMYD3, NSD1, SLC39A8, CDC73, SP1, NES, HBG2, HOXA6, HOXA3, HNRNPA1, SLC29A2, HNF4A, HMGCR, HMGB3, HMGB2, HLA-DRB3, HLA-DRB1, HLA-DQB1, HK2, HK1, HIP1, HTT, HCL2, HCFC1, HOXA13, HOXB1, HOXB2, HSPA4, IFIT3, ID4, MRPL58, TNC, HTN1, HSP90AB1, HSPA9, HSD11B2, HOXB5, PRMT1, HOXD3, HOXD@, HOXC10, HOXB9, HOXB8, HOXB6, HBZ, HBG1, IGF1R, HBA2, GATA6, GATA4, GAS6, FUT3, FUS, GAST, NR5A1, FRZB, FRA7G, FRA6F, FXN, FPR1, FOLR1, FOLH1, FMOD, FLNC, FOXO1, GCY, GGT1, B4GALT1, GPR42, HBA1, H2AZ1, GTF2H1, GSTA1, GRM3, GRB10, FFAR2, GPER1, GHRH, GPI, GNB2, GNB1, GLS, GLI2, GLI1, GJA1, IFNB1, IGF2, VEGFD, LRP6, RAB8A, ME2, MDK, MCM7, MCM3, MBL2, MATK, MAL, MAGEA3, SMAD7, SMAD5, EPCAM, SH2D1A, LYN, LY9, LTK, LTF, MET, MIF, MIP, COX1, NAIP, MYBL2, MUSK, MTX1, MTR, CYTB, MTCP1, MSX1, NR3C2, MST1R, MSR1, MOV10, MNDA, MNAT1, MMP7, MMP1, LTB, LRP1, IGFBP2, LRMP, JUND, JUN, JARID2, EIF6, ITGB1, IRF2, ITGA6, IRAK1, INS, IL15RA, IL12B, IL9, CXCR1, IL2RB, IGL, IGHM, IGFBP4, CD82, KCNH1, KIR2DL1, LAMP1, LOX, LLGL1, LIMS1, LIG3, LDHA, LCN2, LAMP2, LAMB3, KIR2DS1, LAG3, AFF3, KRT19, KLRC1, KIR3DL2, KIR2DS5, KIR2DS4, FIM3, FHL2, NEDD8, BMX, CBS, CBR1, CASP10, CASP5, CAMP, CAMLG, CAMK4, SLC25A20, DDR1, CA2, FMNL1, VPS51, C5AR1, C4BPA, BRS3, ZFP36L2, BPHL, CCKBR, CCND2, CCND3, CD79B, CEBPE, CDX4, CDR1, CDK8, CDK5, CDH13, CDC34, CD68, CCNG2, CD58, CD37, TNFSF8, CD86, MS4A3, CD247, CD2, BNIP3, BMP6, CHD1, BMP2, AMH, ALOX15, AKT2, AIC, JAG1, ADRA2B, ADRA1A, PARP4, ADD1, ADCYAP1, ADCY7, ADAM10, ADA, ACVRL1, ACTG1, ACP1, ABR, ANGPT2, ANK1, ANXA7, ATP2A3, PRDM1, BDNF, TNFRSF17, BCL2L2, BAK1, BAG1, ATP7A, ATIC, AOX1, ATF4, SERPINC1, ASS1, ARNTL, APOE, APOBEC1, APCS, RCBTB2, AKR1C4, FGFR2, DOCK2, EPAS1, ENO2, MARK2, EIF5A, EIF4EBP1, EGF, EFNB2, EFNB1, PHC1, EDNRB, EDNRA, DVL2, DVL1, DUSP2, TSC22D3, ARID3A, DPYD, EPHA1, EPHX1, ERBB2, F8, FCGRT, FCGR2B, FCGR2A, FCER1A, FAT1, FASN, FABP4, EZH1, ERBB3, EXT1, ETV5, ETS2, ERN1, ERF, ERCC5, ERCC1, DPP4, DNM2, CHGB, DNA2, CTBP2, CSPG4, CSNK2A2, CSNK2A1, CSHL1, CSF2RB, CSE1L, CRP, CRMP1, CR2, CR1, CNR2, LTB4R, CKB, CHRNA4, CHRM3, CHI3L1, CTF1, CTLA4, CTNND1, DES, DMBT1, DLX4, DLX3, DLD, DLAT, DHODH, DFFB, DEFB1, CTSL, DDIT3, DGKA, DAG1, DACH1, CYP24A1, CYP3A4, CYBA, NDN, NEDD9, GIPC1, RNF217-AS1, THOC5, PIAS1, BLZF1, DGKZ, IKBKG, PARG, PPM1D, SMARCA5, FZD9, FZD4, ARID1A, USP9X, GATD3A, TAM, MIA, COIL, ANC, EIF3A, EIF3D, TNK1, ASAP2, NOL3, SLC5A6, FUBP1, SQSTM1, VNN2, PER2, LDB1, ALKBH1, HRK, KSR1, GGH, NRP2, TNFRSF10C, TNFRSF10D, TNFRSF11A, TNFRSF18, RASSF7, LAP, CH25H, CP20, VCP, USP1, UQCRFS1, NR1H2, UNG, UMOD, UGT1A, UFD1, SUMO1, UBE2E2, TYK2, TNFSF4, TTN, TRAF3, TRAF1, TPT1, TP53BP2, VDAC1, VEGFC, VIM, ZFX, PAX8, EVI5, ZYX, ZNF224, ZMYM2, TRIM25, MZF1, YWHAZ, VIP, XRCC4, XPC, WNT7A, NSD2, VWF, VPREB1, VIS1, F2RL3, SPAG9, TNFAIP3, BCL2L11, FST, ARIH2, YAP1, NDC80, KLF2, HMGB1P5, MRVI1, SMYD5, STUB1, ZMPSTE24, MSLN, TNK2, RBM6, TRIM28, TSPAN3, PTPRU, ABCB6, HOXB13, KAT5, ANP32B, KLF1, PLK4, NUDC, NFAT5, USP39, CD226, CTCF, CXCR6, KHDRBS1, GNLY, IGF2BP2, IGF2BP3, POSTN, PDPN, TXNIP, HEXIM1, SH2B2, SMC4, HDAC6, DOK2, SCO2, ADAMTS1, TJP2, LPXN, RAB9A, SLIT2, PDLIM7, UBE2L6, MSC, NOG, PTTG1, DCLK1, IL1RL1, LPAR2, CBFA2T2, INA, FCGR2C, USP10, LITAF, TBPL1, NPEPPS, HDAC4, HNRNPDL, SLC23A2, FCHSD2, SETDB1, GAB2, PCLAF, TOX, SOCS5, BAG3, IKBKE, FEZ1, CLCA2, NCOR2, NCOR1, RIN1, APOBEC3B, TNR, NR2E1, NF2, PLG, PRKAA2, PRKAA1, PPP5C, PPP2R5C, PPIB, PPBP, PPARA, POU4F1, POU3F1, POU2F1, PON2, PON1, POMC, SEPTIN5, PRRX1, PMAIP1, PLN, PRKAB1, PRKCA, PRKCB, PTAFR, PTPRA, PTPN13, PTPN1, PTN, PTGS1, PTGER4, PTCH1, PSEN1, PRKCD, PROS1, PRL, MAP2K5, MAP2K2, MAPK9, MAPK11, PRKDC, PLEK, PLCG2, PVALB, PLCG1, P2RX7, P2RX5, OPRK1, OGG1, OAZ1, NUMA1, ROR2, NT5E, YBX1, NOTCH4, NPY, NME2, NNAT, NHS, NFE2, NFATC3, NFATC2, P2RY1, PAK1, REG3A, SERPINA4, PLAG1, PLA2G1B, PKNOX1, PKD2, PITX2, PIK3R2, PIK3R1, SERPINA1, PAWR, SLC25A3, PGD, PFDN5, PER1, PCM1, PAX6, PAX2, PTX3, RAB27A, TLR3, SMARCA2, SULT2A1, STC1, SSX2, SSTR4, SST, SSRP1, TRIM21, SPARC, SOX12, SOX11, SOX10, SOX2, SOS1, SOD2, SNCA, SIGLEC1, SMPD1, SUV39H1, TACR1, MAP3K7, TERF2, TLE1, TK1, TIE1, THRB, THOP1, TFR2, TFCP2, TMBIM6, TALDO1, TEF, TRGC1, TRG, TRB, TCN2, TCF7L2, TAP1, SMARCD2, SLN, RALA, SLC22A4, RPS6KB1, RPS6KA3, RPS6, RPN1, RPL22, RPL15, RORC, BRD2, RMRP, RHEBP1, RFC1, RBL1, ARID4A, RASGRF1, RARRES1, RARS1, RARB, RRAS, S100A10, S100A11, SHH, SLC19A1, SKP2, SIX1, SIM2, PMEL, SIAH2, SHMT1, SHB, CLEC11A, SH3BP2, SFRP5, SFRP1, SEMG1, SELPLG, SEL1L, CCL18, MIR223HG
    • Leukemia Mayo_clinic
      Overview Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system. Many types of leukemia exist. Some forms of leukemia are more common in children. Other forms of leukemia occur mostly in adults. Leukemia usually involves the white blood cells. Your white blood cells are potent infection fighters — they normally grow and divide in an orderly way, as your body needs them. But in people with leukemia, the bone marrow produces an excessive amount of abnormal white blood cells, which don't function properly.
  • Pancreatic Cancer Wikipedia
    The AJCC-UICC staging system designates four main overall stages, ranging from early to advanced disease, based on TNM classification of T umor size, spread to lymph N odes, and M etastasis. [56] To help decide treatment, the tumors are also divided into three broader categories based on whether surgical removal seems possible: in this way, tumors are judged to be "resectable", "borderline resectable", or "unresectable". [57] When the disease is still in an early stage (AJCC-UICC stages I and II), without spread to large blood vessels or distant organs such as the liver or lungs, surgical resection of the tumor can normally be performed, if the patient is willing to undergo this major operation and is thought to be sufficiently fit. [12] The AJCC-UICC staging system allows distinction between stage III tumors that are judged to be "borderline resectable" (where surgery is technically feasible because the celiac axis and superior mesenteric artery are still free) and those that are "unresectable" (due to more locally advanced disease); in terms of the more detailed TNM classification, these two groups correspond to T3 and T4 respectively. [3] Pancreatic cancer staging (TNM classification) Stage T1 pancreatic cancer Stage T2 pancreatic cancer Stage T3 pancreatic cancer Stage T4 pancreatic cancer Pancreatic cancer in nearby lymph nodes – Stage N1 Pancreatic cancer metastasized – stage M1 Locally advanced adenocarcinomas have spread into neighboring organs, which may be any of the following (in roughly decreasing order of frequency): the duodenum , stomach , transverse colon , spleen , adrenal gland , or kidney . ... Recognition of a non-insulin-secreting type of PanNET is generally ascribed to the American surgeons, R. M. Zollinger and E. H. Ellison, who gave their names to Zollinger–Ellison syndrome , after postulating the existence of a gastrin-secreting pancreatic tumor in a report of two cases of unusually severe peptic ulcers published in 1955. [105] In 2010, the WHO recommended that PanNETs be referred to as "neuroendocrine" rather than "endocrine" tumors. [25] Small precancerous neoplasms for many pancreatic cancers are being detected at greatly increased rates by modern medical imaging.
    BRCA2, TP53, CDKN2A, STK11, KRAS, BRCA1, SMAD4, EP300, PALB2, ABO, NR5A2, MYC, CTNNB1, TNF, MMP2, AKT2, APC, PDX1, PTEN, PTGS2, STAT3, ATM, KDR, CXCL8, TYMS, SST, TNFSF10, TERT, EGFR, TGFB1, HIF1A, MSLN, CD44, SPINK1, MMP9, PPARG, CD24, LDHA, PLAU, SOD2, PALLD, SSTR2, SLC29A1, MAP2K4, DPYD, TGM2, AXL, IL24, IFNA1, PTCH1, EPCAM, NR4A1, TFPI2, CDH1, LINC00673, NRP1, RAP1GAP, MEN1, RB1, VHL, WT1, KLF5, TYMP, PTHLH, GADD45A, FGF13, CCL20, EFEMP1, CFLAR, AHR, TNFRSF10B, SSTR1, FXYD3, TP63, BAP1, FOXP1, ANXA10, DAXX, NFKBIA, TSC2, RNF43, BUB1, VEGFB, MIR1179, SSTR3, IFNA2, RABL3, SUGCT, CNR1, IFNA5, CNR2, ETAA1, CLPTM1, SYCP1, RBBP8, GAGE1, CCAT1, BCL2L1, BCAR1, LY6E, ZNRF3, ATRX, COL18A1, CLPTM1L, DAB2, SBF2, HSPB2, ERBB2, CCKBR, HRAS, HSPB1, HSP90AA1, LINC01829, PPFIBP1, EPHB2, PIK3CA, CCK, HGF, ERBB3, MIA, PDHX, PSCA, SIRT1, HSPB3, H3P10, PIM3, NOTCH1, CEACAM5, EGF, SMUG1, PIK3CB, PARP1, MAPK1, MAPK8, MTCO2P12, GPC1, CDK4, HDAC9, CEACAM3, ABCG2, ACTB, CEACAM7, LINC01088, MAPK3, NDRG1, PSG2, YAP1, PIK3CG, TAFA5, SLC19A1, SPARC, PRSS1, PROM1, PIK3CD, HP, GLI1, MAP2K7, F3, NGF, ZEB1, FBXW7, NFE2L2, TEX11, ITGB1, VEGFA, GABPA, BICD1, ANXA2, CD82, GAST, DCLK1, COX2, CCND1, XIAP, MET, BACH1, S100A4, LGALS1, MDM2, DPP6, MUC16, FOXM1, MIR21, SLC39A4, MIR221, IFNG, EZH2, LINC00964, AKT1, ALB, LDLRAD4, C9, MUC5AC, SETD2, CXCR4, VIM, MUC4, CD274, LEPQTL1, XRCC1, IGF1, MUC1, IGF1R, CXCL12, IL1B, IL6, BCL2, HNF1A, SCT, TWIST1, CCN2, TLR4, DNMT1, AURKA, CAV1, PLK1, CASP3, PKM, MTHFR, LGALS3, MTOR, BRAF, PRKAA1, MIR301A, AGER, HOTAIR, EPHA2, MCL1, VTCN1, COL11A2, RAC1, DUSP6, CDKN2B, CRP, MAPK14, RUNX3, MALAT1, FN1, MIR155, MIR210, ERCC2, DCK, AGR2, CFTR, GDF15, CDKN1A, ADIPOQ, PRKN, MIR200C, TIMP1, KIF20A, PTF1A, PSMD9, TGFBR2, TICAM2, RRM1, MIR137, MIR142, ALOX5, MLH1, MIR29A, SOCS3, IFI27, SRC, GLP1R, PRKAA2, SP1, SOX2, TMED7-TICAM2, HMGA1, SOAT1, H3P23, PAK4, CHEK1, ZNRD2, BMI1, HMGA2, RALBP1, PALD1, TMED7, TLR7, BSG, DCTN6, WNT5A, EPAS1, WEE1, POSTN, BNIP3, MST1, FGFR1, ATN1, MST1R, GSK3B, PRKAB1, CD47, NFATC2, HSPA5, FANCG, PVT1, SHH, MBD1, ETS1, NPTX2, ABCB1, SLC2A1, MUC2, IFNA13, MMP7, MRC1, IGF2, CCN1, NQO1, LUM, MDK, IL10, PTPA, ELAVL2, POU5F1, FLT1, CXCR2, GSTT1, AIMP2, DKK3, MIR23A, KLF10, CRK, MIR214, MUL1, MIR203A, MIR200B, MIR195, APEX1, GRAP2, MIR145, CDKN1B, MIR141, RIPK1, TNFRSF6B, NR1I2, LINC01194, TGFA, THBS1, ALDH1A1, POLDIP2, MICA, NES, HOTTIP, UCA1, POU5F1P4, MIR34A, POU5F1P3, RNF19A, CASP8, CBLL2, CTLA4, AHSA1, RUNX2, ERCC1, OGG1, FANCC, ZG16B, DNER, NTRK1, FGF2, F2RL1, MMP14, FOXO3, CD276, NUPR1, RMC1, MSH2, AFAP1-AS1, DCC, LIF, MIR10B, HDAC1, HDAC2, HMGB1, ACTN4, HMOX1, ADM, ADRB2, IAPP, ICAM1, GDNF, MIR96, MIR25, IL1A, IL2, MIR223, MIR212, MIR205, ANXA1, MIR148A, MMRN1, MIR143, LCN2, MIR132, REG3A, TMEM97, UQCRFS1, STAT1, RET, TGFBI, CDC42, DPP4, CDK2, KLF4, CTNND1, IL32, DSPP, BAG3, CUX1, VDR, TAZ, PIM1, PCNA, SOX9, SEMA5A, XPO1, MAP2K1, SUB1, PRKD1, SPP1, JUN, TOP2A, MLRL, XIST, RAF1, IL4, IL4R, VEGFC, MIR222, MIR216A, NAT2, IL13, MOK, RAD51, TP73, JAK2, MIR23B, MIR29C, IGFBP3, MIR506, SMARCA1, SLC5A5, H3P9, COMMD3-BMI1, SNAI1, HK2, HLA-A, SKP2, SSTR5, FOXA2, SDC1, HSF1, CCL5, MIR27A, MIR494, MIR429, TNC, RRM2, MIR335, MIR17HG, TRA, RREB1, ROCK1, MIR30A, L1CAM, TEAD1, NCOA3, IKZF3, STMN1, BHLHE40, ESRP1, NT5C3A, IL22, PLEC, NXT1, SLC22A3, IL17B, ZEB2, NF2, NFATC1, TSPAN1, CIB1, CACYBP, MRPL28, PDPN, NFKB1, WWTR1, IGF2BP3, BRD4, HPSE, NRAS, NTSR1, COPS5, SERPINE1, PAK1, SIRT3, CDK14, PARPBP, PACC1, MSX2, TP53INP1, SOCS1, LEP, TBC1D9, MIR107, LGALS4, DUSP28, MTA1, PRKCA, UPRT, TM4SF1, LPAR2, SMAD2, MAGT1, MUC13, REG4, VMP1, LONP1, EHMT1, MMP1, FTO, TRPM8, GAS5, NDRG2, KEAP1, ACKR3, SLC12A9, ADAM9, NAT1, CDK6, GEM, GCG, CALR, CDKN3, FGFR2, ADH1C, CCR6, GLS, FHIT, CSF2, FOS, ALDH2, ACVR1B, FKBP5, FOXO1, ALPP, ALPI, GATA6, CETN1, ASS1, TIMM8A, CLDN7, F2R, TSACC, GPRC5A, ADH1B, HULC, FOSB, CASR, PCLAF, SMARCA4, DECR1, CDX2, CDK5, EPHX2, RCBTB1, FSCN1, SOX4, FLT3, MIR663A, LGALS9, UGT1A7, MIR217, CEL, CYP17A1, CLDN1, TRPM7, ISG15, CLOCK, MIR345, SET, CDK7, MIR200A, MIR216B, JUNB, JUND, ADAMTS1, KL, ITGAM, SERPINF1, SFTPD, SHC1, SELE, ITGA2, HDAC3, ARNTL, PBK, TUG1, SLC16A1, PDGFRB, DCN, RGN, KISS1, CHI3L1, SREBF1, IQGAP1, BSND, FGF7, ZNF35, VASH2, YY1, ESR1, AGT, PEAK1, TFF1, TFRC, NOTCH3, EZR, COX8A, FBP1, CLDN4, HAVCR2, VAV1, CRYZ, FASN, TIMP2, MUC6, TSPAN8, MYB, MIR196B, TXN, MIR330, ATF2, MIR31, IL33, AGTR1, VSIR, CES2, LOXL2, TNFRSF10C, PGK1, SSTR4, ABCC3, PEBP1, CEMIP, CLIC1, EGLN3, ADRA1A, PRDM14, HHIP, SLC52A2, MIR29B1, CDCP1, ADRA2B, MIR29B2, TAM, KLK7, MAP3K1, CCR7, ALCAM, MAP3K7, MGMT, MIF, CXCL10, EDNRA, NEK2, RASA1, TPX2, NEAT1, EEF1B2P2, PRMT1, GJB2, KDM1A, APLP2, CXCR6, RBM14-RBM4, MIR146A, GJA1, KANK2, NOX4, REG1A, USP22, MIR150, CA9, HTC2, MAP2K2, CD40, GGT1, GPR42, DKK1, MIR15B, E2F1, PDCD4, FAS, AREG, HHLA2, GOLGA6A, HPGDS, BHLHE22, HNRNPA2B1, MCAT, GOT1, SLCO1B3, RGCC, EIF4E, LILRB1, MIR106B, NRG1, PTK2, PHGDH, PWAR1, CCKAR, ARF6, GSTP1, MSH6, MARK2, EBI3, IGFBP1, S100A8, CDK1, S100A9, RBPJ, S100A11, CAT, GATA4, MIR191, SATB1, CDA, MIR1247, ENO1, CBX7, DNM1L, ABCC5, SERPINA1, SCO2, ARL2BP, BRS3, CHST15, CHEK2, GRP, AKR1A1, GSTM1, PLG, ECT2, PRNP, RPL10, SDF4, MIR17, RBM14, MIRLET7B, PLAC8, ADH1A, TRIM29, THY1, NAF1, C17orf97, ASPH, PTPN1, TCF7L2, TWF1, TPD52, PTPN11, TP53BP1, LPAR1, MTDH, TK1, LMLN, TLR1, TNS4, TGFBR1, TFF3, CRY2, CRMP1, AR, FAM83A, PTK6, PTBP1, TFAP2A, E2F3, KISS1R, TGFB2, MAK16, TIAM1, CCL21, TBX2, IDO2, CYP24A1, RFXAP, CASC2, ROBO1, DNM2, ROS1, SMARCA2, RBM45, RPS6KA2, RPS6KB1, RPS27A, ABHD11-AS1, S100A2, RELA, SIX1, TRIM69, SFRP4, ARHGAP4, LDLRAD3, SEL1L, SARDH, RMDN2, CCL2, PDIK1L, TICAM1, CCL18, DNMT3A, LRG1, TAT, DLX6-AS1, TACR1, PTPN14, TAC1, PTPRC, SOX2-OT, RAB5A, SYT1, STING1, GADL1, PRRT2, CDCA5, DUSP1, STK4, CYP2B6, STAT5B, SNHG15, CYP1A1, DPYSL3, DNMT3B, CYP1A2, CYP1B1, OSBPL5, SSAV1, RECQL, SRY, SRF, AZIN2, BHLHE23, TPM3, CD68, IL23A, PRMT3, PSME3, ABCC4, B3GALT5, GOLM1, TUBB3, ING4, PRMT5, WASF2, VAV3, RMDN1, SEMA4D, DESI2, ATG7, ANP32B, CD40LG, FOXP3, GDE1, ZFR, SLIT2, DLL4, MEG3, COX5A, RMDN3, CDH17, HEATR1, SLC52A1, CDH3, PAF1, IQSEC1, NAMPT, MFN2, KRT20, TLR9, BCL2L11, PTPRU, CDC25B, WWOX, CDC20, ASAP1, TXNIP, BTK, PRPF31, KLF8, DDR1, CTRC, BBC3, CILK1, MYOF, ZHX2, NOC2L, SMG1, CD36, SULF1, CASP9, TFIP11, SLC7A8, ANGPTL2, SNHG1, SRRM2, DAPK2, RASSF1, MAP4K1, FSTL1, SRPX2, DELEC1, CELF2, CTCF, CD86, ERO1A, SLC39A3, AP4B1, EEF2K, GIPC1, CD80, UHRF1, TBK1, MCTS1, CD14, SGSM3, RBMS3, WDR5, CDK8, CDK9, TPT1, COL4A2, COL11A1, WNT10B, DHDDS, XPC, XRCC3, XRCC4, BAX, ZFP36, COL1A2, ULBP2, LIN28A, MANF, MCPH1, TUSC3, TCTN1, BHLHE41, CMM, FOSL1, LAT2, VIP, SYBU, UBC, NR2C2, TRAF2, TRAF6, TMPRSS13, CPOX, TTK, ITCH, TYRO3, NUF2, BAG1, ARHGAP24, ATR, AVP, CLDN3, UTRN, KDM6A, UVRAG, VCL, USP5, LTB4R, WNK1, HAP1, KSR1, CDK5R1, PER3, PER2, PNO1, SQSTM1, BNC1, DIABLO, METTL3, USP9X, TM4SF5, ARTN, AIP, DMAP1, SLC16A4, SLC16A3, DYRK1B, BUB3, CES1, CCN5, CFL1, CHPT1, CMA1, GORASP1, ROBO3, CUL4B, IL21, CIP2A, DENR, CLU, DANCR, TP73-AS1, SMURF1, TNFSF13, AKR1B10, CEACAM1, TNFRSF10D, TNFRSF10A, IL18R1, CCR5, PADI4, MIR629, LINC01672, HSPD1, PAWR, HSPG2, PARN, ITGAV, C20orf181, MME, EPS8, ERBB4, FGF10, ITGA3, GFRA2, PRDX1, SNHG16, MIR451A, PAEP, AKR1B1, MMP11, ALDOA, P2RX7, P2RX5, ALDH1B1, GRK2, MIR296, OLR1, MNAT1, MAP3K10, ITGB2, NTS, MIR204, EPHB4, PFN1, MIR483, KCNJ11, KCNH2, MIR509-1, PER1, PDPK1, MIR497, HOXB7, MIR193B, MIR885, MIR373, HSPA4, ITK, HOXD13, GLI3, PDK1, FGFR4, MICOS10-NBL1, PDCD1, ANGPT1, MITF, TMX2-CTNND1, HSPA2, ANG, IFIT3, ROR2, PHB, TMEM238L, FBN2, MIR1231, IL6ST, IL17A, TNFRSF9, MIR135B, GAPDH, MIR1246, IL9, MTRR, FAT1, MIR148B, FAP, MIR424, MIR375, IL12A, CISD2, NEDD9, IL15, NEDD4, NCL, NBN, NBL1, MUTYH, IL13RA2, MIR374A, MTAP, IL2RA, ADAM8, NPY, NTRK2, NTF3, IRF2, FDPS, MIR1290, FCN2, FBL, GCHFR, PNP, IGF2R, ILK, MSMB, ESRRB, NGFR, NOS2, MIR1291, MSN, MIR1181, FCGR3B, MIR99B, AFP, IL18, NME1, MIR1271, FCGR3A, IKBKB, MIR744, MAP3K5, PRRX1, ELAVL1, POTEF, PPIA, GGT2, APOA2, FOXL1, EIF4EBP1, LASP1, RPSA, CCR2, EIF5A, CXCR3, FOXC1, GGTLC4P, MIR144, BIRC5, PODXL, HFE, UPK3B, HIC1, SNHG14, CDKN2B-AS1, PMS1, SMAD7, MIR15A, MR1, MIR139, LDHB, LTB, GSN, RELN, GRB7, PRSS2, AQP3, EEF1A2, MUC5B, CXCL1, GSK3A, FADS1, MIR601, MIR10A, PRKCB, MIR130B, MIR122, ANXA8L1, PRKAR1A, MIR126, GGTLC3, LRP2, GGTLC5P, ANXA8, EIF4A1, FOLR1, LTA, MAGEA3, CEACAM6, KCNN4, MCC, HNF4G, PCAT1, MCAM, GLO1, HNRNPK, KCNQ1, ENG, MIR196A1, MIR192, MIR185, PLAUR, SLC25A3, PLAT, MAP1A, LINC-ROR, MIR455, FKBP4, MIR181C, MIR183, MIR486-1, FOXA1, BMP8B, PIMREG, MTPAP, ZNF654, RHOF, NLRP2, CCL28, LTB4R2, MRGBP, PRPF40A, MIR874, ERO1B, MIR940, EIF5A2, STYK1, MIR646, MIR92B, IL17RB, LXN, MAML3, FERMT1, SMARCAD1, RIPK4, MIR652, TRPV6, ETNK1, TREM1, TERF2IP, KCMF1, SPHK2, BMP3, CHD7, ANLN, GPR137, MIR374B, MIR935, RETN, STK31, BNIP3L, GACAT2, ADPGK-AS1, OGDHL, CEP55, SNHG9, SARS2, CNDP2, OCIAD1, AGAP2-AS1, INTS11, MIR675, NKRF, ZGLP1, MSTO1, SLC35F6, LINC00462, MIR891B, MIR365A, BOK, PSENEN, ANO1, PIWIL2, KDM3A, PRR11, EXOC2, MIR876, CDKAL1, SULF2, SOX6, NSUN5, MIR1225, SLC38A7, BMP2, DIP, PARP14, KDM7A-DT, UGT1A1, MIR760, UGT1A3, PBRM1, ASPN, LOC729970, BPHL, CC2D1A, RADIL, ST7L, ALKBH5, HHAT, SLC25A36, SYCE1L, DST, MYDGF, MED29, KPNA7, PCBP3, GLS2, ERVK-11, MYB-AS1, LSM1, BANCR, LINC01111, HCAR1, GHET1, CA2, AGO2, SERPING1, LOC102723407, GATD3B, DKK4, SIK1B, CDR1-AS, CAD, CALCR, ANKRD1, SPINK4, MIR5100, UBE2S, RABGEF1, ATAD2, HIPK2, MACROD1, NOB1, ERVK-22, MIR2682, MIR4656, LAMTOR2, REM1, DLL1, SPRY4-IT1, SLCO3A1, SLCO4A1, HTRA2, DESI1, PSC, C3, DNAI1, USP21, SNORA74A, LETMD1, LOC112694756, MOB4, ZEBTR, PRPF40B, LNCRNA-ATB, EML2, CADM1, RAB38, SH3BP4, TMEFF2, ACADS, H3P13, H3P8, ABCA4, FAM215A, DDX58, SERPINA3, USP49, CASP7, IRAIN, LOC110806263, EHF, PERCC1, FGF21, PTPN22, CERNA3, KCNK15-AS1, LINC00976, CAPN1, NUTF2P3, CHD5, SIRT1-AS, ACO1, NECTIN3, CAST, CLIC4, MYRIP, TMEM158, C1GALT1C1, LINC00339, DUOX1, ADAM10, PRKAG2, CRLF3, ZMYND10, MIR1301, MIR1180, MIR634, TLR8, BTC, KLF9, C1QBP, CLDN18, CKLF, ZEB2-AS1, HSPA14, LEF1, MIR663B, MIR4306, ACVR2A, YTHDF2, SIRT6, RAB14, NT5DC3, GPR87, LOXL1-AS1, MBD3, IL17D, LINC00994, BCL11A, ADA2, MAP3K20, CDK12, CMPK1, CAB39, RAB23, SF3B6, MIR1297, PIAS4, MIR1243, MIR1266, MIR3686, A4GNT, INSIG2, IL20, DUOX2, ERVW-1, ACTA2, VSX1, KLRC4-KLRK1, ACP3, UBQLN1, BUB1B, ERVK-2, STRN4, NPC1L1, MIR3064, TSPO, BRD7, MYLIP, ERVK-12, PYCARD, ACVR1, IL21R, IRAK4, PXN-AS1, ANGPTL4, MIR642B, MIR3923, APIP, GMNN, MIR3679, ISOC1, LINC01133, BTF3, ASCC1, SMIM31, TRAT1, LINC00958, F11R, TAS2R10, LINC01006, ARHGEF4, SLC25A37, DIO3OS, EMSY, PROKR2, CD109, ADAT2, GPR151, SLCO6A1, EMB, REG3G, ANPEP, MIR208A, ANGPT2, FATE1, MIR211, TMIGD2, SPNS2, MSI2, ARR3, JDP2, SPPL3, H4-16, CCDC26, MUC17, GATA5, ANXA5, LINC00052, MIR198, MIR199A1, PTGR2, PRIMA1, FBXL14, MIR199A2, MIR19A, MIR19B1, SYT9, MIR20A, CACUL1, ANXA11, ANXA6, TMEM37, BRI3BP, SLC32A1, CYP2R1, TMEM45B, PRAP1, MAL2, MCM3AP-AS1, ALDH1A3, IL17F, MIR28, EGLN2, AGTR2, PPP1R14A, MIR302A, ART1, FOXQ1, ASAH1, DMKN, ASNS, MIR30C1, MARVELD3, LRP5L, MIR30C2, NLRP3, MIR155HG, ALPG, MIR224, MIR215, TWIST2, MRGPRX4, MRGPRX3, DCD, ANIB1, TM4SF18, CMTM5, CTHRC1, MIR219A1, NOSTRIN, MIR22, UHRF2, ALOX15, FBXO32, ALK, CSMD2, MIR197, SIK1, APAF1, MIR127, MCIDAS, MIR129-2, RSPO2, KLK3, ANO9, APRT, CHSY3, TRIM59, APOC1, ARG1, LYPD5, LINC00346, LINC01559, OR10A4, BCL9L, APOA1, SLC25A45, MACC1, PWAR4, SBF2-AS1, DNAAF3, CCSER1, PAIP2B, LINC01121, C16orf74, HRNR, MIRLET7C, SERPINA13P, CEP85L, MIRLET7D, LINC-PINT, MIR100, MIR106A, FASLG, ENTPD8, GSTK1, TMPRSS9, MIR125A, H19, ASPM, MIR193A, MUC20, ARID2, B3GNT6, MIR182, ADAMTS18, OIT3, BHLHA15, OXER1, IFNLR1, SLFN5, EML5, CLEC14A, MIR186, SLC5A8, RHOB, FEZF1-AS1, NKAIN2, DAB2IP, MIR181A2, CENPX, MRGPRX1, MED19, MIR149, SGMS1, NPCA1, FAM133B, ARG2, MIR152, RICTOR, IL27, SEMA3D, BIRC2, GPRC6A, FOXK1, KDM1B, MIR18A, ALKBH3, MARCHF8, VWCE, LINC00473, MIR32, SMYD2, SMURF2, NIBAN2, YTHDC2, PORCN, IL25, DEPTOR, ILRUN, S100PBP, SMYD3, TMPRSS3, PNPT1, HIF3A, COP1, RHBDF1, MMS19, LINC01060, BGLAP, MIIP, SAV1, MIR520H, PINK1, MIR519D, MIR181D, BCL6, DHX40, DYNC2H1, TMEM204, MIR489, MIR146B, BCR, MIR202, PLEKHF1, MIR492, BDNF, MIR493, CFB, GGCT, STK33, ADRB3, CDK15, AFAP1, LGR6, ACE2, SLURP1, ADH4, PNPLA2, CXADRP1, CIAPIN1, ADAMTS9, PRDM1, H3P38, MIR539, SNORA25, MIR421, MIR584, KIF15, OTUD7B, MIR607, MIR608, MIR613, MIR623, CD248, NORAD, IL22RA1, ADH6, SNX6, SINHCAF, HAMP, ANKRD36B, KLHL1, MRTFA, CFAP97, PCDH10, CERNA2, CRNDE, MIB1, RPTOR, ARID1B, PPM1H, BGN, AICDA, PARP4, MIR485, MIR410, BCKDHB, VN1R17P, EBPL, GPR166P, FOXB2, XRCC6P5, ZGPAT, NT5C1A, MCHR2, HOPX, MCM8, RAB11FIP4, PROK1, RPAIN, MIR331, AP2A1, MIR340, USP44, MIR367, TRIM63, KDM2B, MIR370, MIAT, TSLP, NKD1, MIR320A, MIR34B, SNHG7, MIR93, JAG1, RAB2B, ATAD1, PARP10, MIR99A, RIOX2, KMT5C, PSRC1, CRISP1, ASTL, HINT2, MYCBPAP, ATF3, SH3D21, PPP1R2C, GRHL2, DUXAP8, JADE1, DUXAP10, NANOG, UBA5, NBDY, MFSD13A, KDM8, MIR448, MIR449A, H4C15, MIR431, MMRN2, MYH14, BCHE, MIR452, NAA25, CEP70, MIR371A, MIR425, RERE, IMMP2L, HASPIN, SUMO1P3, SESN2, VANGL1, NETO2, MIR377, MIR381, MIR384, NECTIN4, AZGP1, ZFP91, ITIH5, SLC44A4, SRCIN1, BAK1, GPX2, HS3ST3B1, LPAR3, PLOD2, EFNB2, PKN1, EGR1, PRKAR2A, PRKACG, EGR3, EIF4A2, PRELP, PPP5C, PPP1R1A, PPID, PPIB, MED1, PPARA, PON2, PON1, POLE, POLD1, PNMT, PNLIP, PMS2, PMS2P3, PMAIP1, PRKCZ, PRKDC, EFNA2, PTAFR, PTPRJ, PTPRG, PTPRA, PTPN13, QSOX1, PTN, E2F2, PTGS1, PTH, PTGER4, PSMD10, EEF1G, PYY, PRTN3, KLK10, HTRA1, KLK6, PRSS3, EDNRB, PROX1, EEF1A1, MAPK9, PLXNA1, CELA1, DYRK1A, PLEK, CDK16, PCBP1, PCBD1, PBX3, PAX6, PAX5, PAK3, PAK2, EREG, SERPINB2, ERCC4, PAFAH1B2, PCSK6, P2RY6, P2RY2, OSM, OSBP, ORM1, OPRM1, OPRD1, TNFRSF11B, ERCC5, ODC1, PCYT1A, PDE8A, PDGFA, PIGR, ELK3, PLCB3, EMD, PLA2G4A, PKLR, PKD1, PIN1, EPHA1, EPHA4, EPHB1, EPHB3, PDGFB, PGR, PFKP, PFKM, PFKFB4, PFDN5, PEG3, PECAM1, PDZK1, ENPP1, PDK4, PVR, RGL2, PSD4, SAFB, SLC1A2, DCX, SKIL, SKI, SIM2, ST3GAL4, ST6GAL1, DDB2, SFRP1, DDT, SELP, CX3CL1, XCL1, CXCL5, DLD, CCL8, CCL7, DMD, SRL, SCTR, SCN10A, SCN9A, SARS1, ACE, SLC5A1, DCTD, DAG1, SPP2, CYP2C19, SPG7, CYP3A4, SOX12, SOX15, CYP51A1, SOS1, SOD3, DACH1, SNCG, SLC6A8, DAP, SMO, SMN2, SMN1, SMARCC1, DAPK1, SLPI, DAPK3, SLC9A1, SLC8A1, SAI1, S100B, RAB27A, S100A10, RGS16, TRIM27, REST, REN, RDX, RBP4, RBP1, RBM3, KDM5A, DPEP1, RASGRF1, PLAAT4, RARB, RAP1B, RAP1A, RALA, RAG2, DRD2, HBEGF, RAD17, DVL2, RABIF, RAB27B, RNASE1, RNASE3, RNASEL, RPS8, S100A7, S100A6, DNA2, SORT1, S100A1, RXRA, DNAH5, DNASE1, DYNC1H1, RPS15A, RPS6KA3, RNF2, RPS6KA1, RPL39, RPL34, RPL29, RPL26, RPE65, RORB, RORA, SNORA73A, BRD2, ERG, NTRK3, ERN1, IARS1, GAS6, GATA1, GATA2, GATA3, IGSF1, GC, IGFBP7, IGFBP2, GCK, GCKR, GCNT1, IFNB1, IFNAR1, IFNA17, GCY, GDF2, GDF10, IFN1@, GFPT1, IDH1, ID2, IRF8, ICAM2, CXCR1, GALNT3, GAD2, ITGB4, KRT8, FRZB, FUS, KCNK2, FUT3, FUT4, GABBR1, JAK1, JAG2, EIF6, GABRA3, GAD1, ITGA5, ITGA1, ISG20, IRS1, IRF1, ITGA6, GABRP, INSR, INPP4A, IDO1, GFRA1, HYAL1, NT5E, HTR1D, HLA-DRB1, HLA-DOA, HLA-C, HLA-B, GOT2, GP2, HGFAC, GPI, HDGF, HCRTR1, HCRT, H2AX, H1-5, H1-4, GUSB, GUCY2C, GPT, GSTM3, GPX1, GRM1, GRIA3, GRB10, GRB2, GNRHR, HMGB2, HMGCR, HPD, HTR1B, HSPE1, GHR, GHRH, HSPA9, GJB1, HES1, AGFG1, GPC3, HPGD, HOXB9, GLUL, HOXB8, HOXB6, HOXB2, HOXA1, HNRNPU, HNRNPC, ONECUT1, HNF4A, GLUD1, HMMR, KRT17, KRT18, KRT19, FPR2, NEDD8, MYH9, MYD88, FANCD2, MMUT, TRIM37, PTK2B, MTR, ND2, FBLN2, MT1M, MRE11, MPST, MPO, MPL, MMP16, MMP15, GPC4, MMP13, MMP12, FER, MMP3, GPC5, NELL1, NEO1, NEU2, NQO2, YBX1, NRTN, NPY2R, NPM1, NPC1, CCN3, NOTCH2, NOS1, NOP2, NNMT, NM, NEUROD1, NHS, ETV4, NFYA, ETV5, EWSR1, EYA2, NFE2, F9, F10, NEUROG1, KMT2A, MAP3K9, MKI67, FLNA, LMO2, LMNB1, LLGL1, LIPE, LIMS1, LIMK2, LIMK1, LIG4, LIG3, LIFR, FLNB, LPA, LGALS3BP, FOLH1, LFNG, LEPR, FOLR2, LBR, LAMC2, LAMP1, LAMB3, LAG3, LOX, LRP1, MICB, VEGFD, MFAP1, FH, MAP3K4, MAP3K3, MEF2D, MEF2A, MECP2, ME2, FHL2, MDH1, MATK, LRP6, MAT1A, MAP2, SMAD6, SMAD3, SMAD1, FOXD1, TACSTD2, FLI1, BCAM, LTA4H, SPOCK1, CYP2B7P, SREBF2, MVP, GDF11, TRIM13, RBM5, RBM6, TRIM28, G3BP1, ARFRP1, FRY, LRPPRC, RAD50, PPIF, ACTR2, ARPC4, EDIL3, IL18BP, ABCB6, GNE, HDAC6, AKT3, HNRNPDL, NUP153, NR1H4, NR1I3, TRIB1, CNKSR1, SF3B4, CD74, DDX17, CD63, SEMA3C, CARM1, CAP1, MERTK, TACC3, GPNMB, BASP1, RACK1, DLC1, CDK2AP2, IRF9, TUBA1B, MICU1, KLF2, WARS2, TLR6, TNIP1, RTN3, SF3A1, STUB1, MED12, USP15, MSC, GPX4, LITAF, MAGED1, ROCK2, ATG5, RASAL2, MAP4K4, AIM2, GSTO1, QKI, NTN1, RECQL5, CD101, KIF3B, SLC9A3R1, SLC9A3R2, CD163, SOCS6, SNORD22, ADGRG1, BCL7B, PIWIL1, MAPKAPK2, AIMP1, SCAMP1, BAG5, CDH13, SDC3, DLEC1, KIF14, NUAK1, TLK1, CDC25C, MTSS1, SETD1A, USP34, CDH5, DCAF1, MDC1, PTGES, SOCS5, TTLL4, WTAP, PRDX6, APOBEC3B, SPAG6, CDH11, CHD1L, CXCL14, EI24, NEBL, CD59, ARPC1A, HTATIP2, KLRK1, ARHGEF15, MLXIP, FASTKD2, NLRP1, VASH1, CCNA2, ITGA11, CBX3, TUSC2, PDAP1, PHB2, GPR182, SLCO2B1, KLF12, FILIP1L, SLC6A14, GALNT5, CCNB1, WIF1, MAP4K5, RPP14, ADAMTS8, KIFAP3, SIRT2, STK38L, NCAPH, ZNF281, PES1, ICMT, CELA3B, GPR161, TPSD1, CAV2, RUNX1, SIRT4, DICER1, NCSTN, CBR1, SATB2, SIN3B, BICD2, MPRIP, CBL, KDM6B, PEG10, KDM4C, PDS5B, TNIK, RER1, TRIM31, TOPBP1, KHDRBS1, PLK2, KDM5B, RBBP9, PLK4, NFAT5, POLQ, USP39, CCT8, DLL3, TNFSF13B, SPINT2, WASF3, SCGB1D2, IGF2BP2, CD34, IGF2BP1, ENTPD1, PDLIM5, SLCO1B1, ENTPD2, SMC2, OLFM4, SEPTIN9, FRS2, UBE2C, STIP1, OGFR, RIPK3, DSTN, RAB31, CCND2, CCND3, KCNQ1OT1, COPS6, FERMT2, CKAP4, CCNG1, CD28, EHMT2, PAPOLA, GADD45G, BRD8, MALT1, PPARGC1A, MRPS30, NMU, ME3, ADAM28, GCNT3, CDKN1C, SRPK2, TNFAIP1, COMP, COMT, SLC31A1, CPE, NR1H2, UCK2, UGT1A, UGP2, UCHL3, UCHL1, UBE2N, CPN1, TULP3, TUFT1, TTR, TRH, HSP90B1, TPO, TPD52L2, CREBBP, CREM, TOP1, TNFRSF1B, BEST1, TRPV1, VTN, XRCC2, NELFE, DEK, SCLC1, PAX8, BTG2, ZNF154, ZBTB16, CNBP, ZFX, YES1, COL5A2, WARS1, COL6A1, XPA, XK, COL6A2, COL6A3, WNT7B, WNT2, WNT1, COL17A1, WAS, TNFRSF1A, CRKL, PTTG1, CLDN5, CTPS1, HNF1B, CTRL, TBX3, TCEA3, TCEA2, TCEA1, CTSB, TAGLN, ADAM17, CTSD, SULT1A1, CTSE, CTSH, STIM1, CX3CR1, STAT2, CXADR, ST13, CYP2A6, CYP2A13, SSR2, TRIM21, CST1, PPP1R11, TDG, CS, TMSB4X, TMPRSS2, TM7SF2, TLR3, TLR2, TLE1, CRY1, THBS2, THBD, THAS, TGIF1, PRDX2, CSF1R, TGFB1I1, CSF3, CSN2, TFF2, TFCP2, TF, CSNK2A2, TERC, VCAN, TFEB, COL1A1, CNC2, ABCC2, SPHK1, ARHGEF7, IER3, ASAP2, DLEU2, CCN6, NRP2, INPP4B, CHGA, RAB11A, CHKA, ADAM15, CHRM3, CHRNA7, TNK1, BECN1, EIF3F, IRS2, DYNLL1, CLCA1, NUMB, PTCH2, RUVBL1, FUBP1, NAE1, MBD2, ATP6V0D1, MTA2, AURKB, CDKN2D, ARHGEF2, SCAF11, TMSB10, EBAG9, EXO1, ATG12, CCNE2, CDO1, WASF1, DIRAS3, CLDN8, CDX1, BRSK2, CLIC3, MAP3K14, F2RL3, CEBPB, P4HA2, CDK5R2, NOP14, AKR7A2, MADD, UBL4A, H4C11, H4C12, H4C6, H4C4, H4C1, FZD6, FZD4, CDC7, H4C9, ARID1A, GATD3A, H4C8, SLC7A5, ANP32A, GPR68, YEATS4, KMT2D, MFAP5, RASSF7, ADAM12, SLC25A16, CUBN, H4C3, H4C2, LMO4, TTF2, HAT1, PARG, PIK3R3, PPFIA4, CLTC, GEMIN2, SEMA7A, OGT, SORBS2, KLF11, DOC2A, H4C5, RAD54L, STK24, TAGLN2, SPARCL1, PIP4K2B, PIP5K1B, PIP5K1A, NME5, H4C14, H4C13, H3P40
    • Pancreatic Cancer Mayo_clinic
      Overview Pancreatic cancer begins in the tissues of your pancreas — an organ in your abdomen that lies behind the lower part of your stomach. Your pancreas releases enzymes that aid digestion and produces hormones that help manage your blood sugar. Several types of growths can occur in the pancreas, including cancerous and noncancerous tumors. The most common type of cancer that forms in the pancreas begins in the cells that line the ducts that carry digestive enzymes out of the pancreas (pancreatic ductal adenocarcinoma). Pancreatic cancer is seldom detected at its early stages when it's most curable.
  • Esophageal Cancer Wikipedia
    ISBN 978-0-19-983012-1 . ^ a b c d e f g h i j k l m Pennathur A, Gibson MK, Jobe BA, Luketich JD (February 2013). ... PMID 21602001 . ^ a b c d de Jonge, PJ; van Blankenstein, M; Grady, WM; Kuipers, EJ (January 2014). ... S2CID 19933001 . ^ Berry 2014 , p. S293 ^ Ross P, Nicolson M, Cunningham D, et al. (April 2002). ... PMID 24834141 . ^ a b c d e Arnold M, Soerjomataram I, Ferlay J, Forman D (October 2014). ... Retrieved 28 April 2014 . ^ Vega, Kenneth J.; Jamal, M. Mazen; Wiggins, Charles L. (June 2010).
    CDKN2A, EGFR, PTGS2, WWOX, TP53, LZTS1, DCC, RNF6, TGFBR2, ADH1B, ALDH2, CASP8, MIR21, ERBB2, BCL2, CCND1, MIR145, ABCB1, XIAP, PRDX1, RUNX3, MET, LGALS3, PRDX2, SOX2, MMP14, KDR, XRCC3, BAX, SOD2, SERPINB3, MIR200C, TPM1, CDH13, MLH3, NR1I2, WIF1, CXCL2, ABL1, ACTB, ZNF667-AS1, MARCHF8, ALOX15, SFN, MIR98, PTGS1, GAPDH, GNG7, TNFRSF10A, CCNH, UCHL1, TPM4, GRIK2, CYP19A1, CYP26A1, PHB, MAP3K3, TGM2, MT1G, SST, CSF3, NOS2, CRYAB, SNAI2, NOS3, TUFM, ENO1, AKAP13, SMYD2, SLC30A7, MACIR, BCL2A1, AQP3, RPRM, TRMT11, GHRL, BBC3, ADH7, MYC, IL5, CXCL1, MXI1, HMOX1, CTNNA1, PLCE1, STK11, MUC1, RHBDF2, SLC52A3, HLA-A, RUNX1, SLC39A6, ADH4, CHEK2, PCAT1, ERCC1, FKBP1A, MGMT, FLACC1, PEBP4, TMC1, MTHFR, LINC01504, MTAP, CCDC63, DGKH, GSTM1, SDCBP2-AS1, TSPAN11, STEAP1B, MCC, HECTD4, KIT, TEX41, IL6, LINC01405, OCA2, PLCE1-AS1, SLC25A24P1, GSTT1, GSTP1, JAZF1, PIK3CD, PDE4D, TBL2, TFDP1, HEATR3, SEMA5B, TNF, TRPC4, CD274, XBP1, ZFAND5, STAT3, CUBN, SMUG1, IL18R1, PES1, SMG6, KANK1, IKZF3, ABCC8, SREBF2, PDGFRA, PTPN2, SGF29, PIK3CA, PIK3CB, PIK3CG, MAPK1, PTEN, AGBL4, SPINK7, ACAD10, ST6GAL2, SDHA, SDHB, SDHC, ST6GAL1, FAM167A-AS1, FAM167A, VEGFA, H3P10, CYP2E1, AKT1, CDH17, AMPH, CLN3, CRP, CSNK1A1, CTNNB1, AHR, CYP1A1, CALR, CALCR, MDM2, CEACAM5, SLC6A8, HIF1A, TGFB1, NQO1, MIR203A, COX2, EGF, EPHX1, CDKN1A, APC, XRCC1, IGF1, VEGFC, AKR1A1, EPHB2, FHIT, PRM3, MIR34A, RAD51, RARB, IL10, UCA1, TERT, MIR375, IGF2, MMP2, TP73, MTCO2P12, GLI1, CXCR4, PPARG, CCK, EPCAM, MMP7, BMI1, IGFBP3, PCNA, RASSF1, HPSE, OGG1, DNMT1, TMPRSS11A, HPGDS, ECRG4, YAP1, SLC12A9, CDH1, TWIST1, BSG, NAT2, FGF2, EZH2, EGR1, DPYD, IGF1R, ARHGAP24, E2F1, CDK2, MMP9, AURKA, MALAT1, PDCD4, COMMD3-BMI1, BRCA2, FAS, IL1B, MIR93, MIR143, IL18, CDKN2B, TLR4, CKAP4, S100A4, MAPK3, KRAS, FOXA1, PDPK1, ERCC2, ALB, TP63, TNFSF10, ALDH1A1, IFNG, SOX4, PROX1, BHLHE40, CTAG1A, IL1RN, CST3, SOX17, CXCL8, AVP, TYMS, SLCO6A1, CTAG1B, IDO1, VDR, GSTK1, CASP3, BAGE4, PRKCI, CTTN, MIR141, CASC9, PDK1, GNAS, ATAD1, AR, LATS2, MIR139, ADH1C, LOXL2, CDK4, ZNRD1, MIR10B, DELEC1, PLCL1, ABCG2, HMGB1, CYP2A6, LINC01194, MIR214, TERC, CDKN1B, MIR155, ORAI1, PLK1, CXCL12, SERPINB4, CEACAM3, F2RL1, BIRC5, FOXQ1, NKD2, SKIL, CDKN3, SKP2, FASLG, CCNB1, IL27, IL23R, PRKAA2, LGMN, MIRLET7C, MIR100, MIR107, PRKCA, PRKAB1, PRKAA1, PSMB8, POU5F1, POLR2E, POLB, PLAU, MIR144, PKM, PSG2, PTK2, PAQR3, CEACAM7, ANXA2, RPS6KB1, ANXA1, ANGPT1, RPE65, DACT2, RNF2, PTK7, REG1A, RBBP6, RB1, FAP, RARA, SLC39A5, HAVCR2, CDC34, SOX9, ZEB2, CTAG2, CRNN, GEMIN4, CLOCK, KLF4, PTTG1, MTA1, BCL2L1, IL17D, HSPB3, BAG1, SPHK1, RUNX2, KAT2B, PROM1, CCN4, UGT1A1, IST1, BRCA1, SPP1, NXT1, NLRP1, RIPK3, DKK1, RAB40B, SUB1, TBC1D9, ENG, SIRT1, MRPL28, SNHG1, NDRG1, TUBB3, PSMD14, BUB1B, UBE2S, CHAF1A, FRAT1, ERBB4, TNFRSF10B, FEV, LY6K, ANKRD36B, EIF4EBP1, GAS5, TTK, TRAF6, BHLHE41, TP53BP1, CDC25B, TNFAIP3, ZC3H12A, TGM3, PDCD1LG2, CLPTM1L, EIF4E, CDK6, AFAP1-AS1, SRC, UNG, UVRAG, CD38, FERMT1, AXL, ZNF654, FBXW7, AXIN2, MEG3, ADAM12, TUSC3, TENM3, WNT1, MYDGF, DIABLO, XRCC4, EYA4, XK, CD34, TP73-AS1, PIN1, SATB1, MIR146A, MIR29C, IL17A, CXCL10, IRF2, MIR148A, JUN, JUNB, JUND, POU5F1P4, POU5F1P3, KRT16, MIR483, MIR193B, SMAD4, MIR451A, MAGEA3, MAL, CTSB, MDK, MKI67, MLH1, MIR377, ABCC1, MSH2, FGF13, MIR301A, MIR576, IL12B, CXCR2, HGF, H3P9, GJB2, GML, GRB7, CCAT2, FALEC, GSN, GSTM2, GSTM3, H2AX, HDAC1, MTOR, IL2, UBE2K, ADAMTS9-AS2, CD24, HRAS, HSPB1, HSPB2, HSP90AA1, HOTAIR, FOSB, FOS, IL1A, MAPK14, SNORD116@, CASP10, MIR199A1, MIR199A2, MIR183, PEBP1, ODC1, NQO2, CRYZ, FGF7, NRDC, MIR27A, FBXL19, UGT1A8, MIR200A, GAEC1, DLL4, AKT2, MIR20A, MIR873, MARCHF5, OTUD4, MIR122, MIR543, CRCT1, KRT20, TLR9, PARP1, SIRT6, NT5C3A, SLC25A37, DACT1, LINC00184, CHST15, ZMYND10, UBR5, IL23A, SYCE1L, MIR1294, ELK1, MIR126, SPA17, ADAR, XAF1, NANS, TDRG1, FBLIM1, NBAT1, CT47A4, SAGE1, SOX6, MIR206, OTUB1, DSG3, CT47A5, MFN1, CT47A6, CHFR, ACSS2, CT47A8, ERBIN, CT47A9, STK31, CT47A10, MIR210, BDH2, ZNF331, TMEM176A, HULC, LAPTM4B, ACP6, TRIM44, RNF111, SYTL2, MAGED4, TUG1, CT47A1, MIR204, SLC52A1, ANO1, SBNO1, NAT10, QRSL1, MIR205, CT47A2, CHDH, CT47A3, IGF2-AS, LINC01234, PANTR1, BNIP3, CSAG2, SEMA3B-AS1, LINC01617, KCNH4, SLC44A1, ANGPTL2, SLC25A20, SEC14L2, PADI4, CA2, MIR186, PLA2G15, TMEFF2, C4BPA, LINC-ROR, MIR187, PRDX5, MPRIP, CERNA3, PEG10, SBNO2, OIP5, RRAS2, CASP1, PUF60, H3P17, ZHX2, MIR150, MMRN1, MIR16-2, RAB3GAP1, MIR152, TPX2, TPM1-AS, DNMT3B, KDM1A, SMG1, RNF19A, MTHFD1L, POLDIP2, IL22, MIR197, PSAT1, CT47A12, MIR129-2, MIR198, STOML2, MIR127, CYHR1, MIR140, CCAT1, DDX11-AS1, F11R, FOXP3, NDUFA13, LEF1, ATP6V0C, HOOK2, ACTA2, ZBTB20, EMP3, RGS22, PHGDH, NKX2-8, ABO, DNM3OS, MIR550A3, PABPC1, LAMP3, DROSHA, MIR192, IL37, RPL17-C18orf32, EMP1, MIR196A1, MIR196A2, ACACA, C1GALT1, MIR296, ELANE, RHOXF2, MIR423, TSPAN18, EMILIN3, ABCB5, DHCR24, WDR20, MIR382, FFAR4, MTDH, SCGB3A1, NAF1, MIR361, PRRT2, MIR374A, MIR373, FBXO32, APEX1, TSLP, DUXAP8, BAGE3, PWAR4, MIR494, ARG1, MIR202, MIR146B, ACCS, CCDC54, MIR491, RIOX2, DUXAP10, SOX2-OT, MIR433, VSIG1, AQP4, MIR20B, MIR363, SNHG7, MIR372, KLF17, OSR1, JMJD1C, ZFP82, ATN1, MIR96, ADAMTS16, MIR34B, DSC2, MIR31, ALOX15B, CBLL2, FOXK1, MIR30E, MIR30B, MIR302A, CT47A11, ALOX5, MIR24-1, MIR17HG, LRATD2, EPHA2, LINC00261, KCNH8, MIR340, CKS1BP7, CTCFL, TMED10P1, RPL34-AS1, MIR339, OR2AG1, AGER, DACT3, ANXA7, MIR338, PDIK1L, MIR335, MIR326, MIR302B, LINC-PINT, MIR498, CRISP1, MIR499A, USP28, KIAA1522, MIR574, SUGP1, MIR556, IL21, RERE, ZNF667, MIR219A1, GOLPH3, MIR542, MIR539, GORASP1, CDCP1, MARCKSL1, RSRC2, VLDLR-AS1, MIR212, KLHL1, MIB1, SLC44A2, ADAMTS9, IS1, ACKR3, MIR655, AKR1B10, MIRLET7G, CYSLTR2, MIR625, POTEG, MIR601, DANCR, S100A14, NDRG2, TENM2, INTS2, MIR593, WNK1, TRPM8, FSD1, MIR506, MIR487A, ZFHX3, MIR486-1, MAGED4B, NECTIN4, TSC22D4, MIR224, MIR502, ALPK1, ARSA, ARNTL, CRISPLD2, USP26, FSD1L, PHF6, SARNP, WNT10A, RNF34, ALCAM, VTCN1, MUL1, CT47A7, FAT4, DPP4, MIR221, ATM, NEIL1, LIN28A, CSAG3, FBXO31, RASSF10, NANOG, WLS, GRHL2, NAA25, C17orf97, SSX2B, XRCC6, CAV1, PDHA1, CDK14, PGD, PGF, COL11A2, COL6A3, CNTN1, CNR1, PIM1, ABCC2, LTB4R, PLA2G2A, PLG, PRRX1, PON3, POR, POU2F1, POU5F1B, PPL, PRKCB, CCR5, MAPK8, MAP2K1, MAP2K3, PECAM1, PDGFRB, MAP2K7, CLDN4, TRIM37, CSF2, MYD88, GADD45B, NF2, NGF, NOTCH1, NPAS2, CRMP1, FGF4, SLC22A18, CRK, PAH, SERPINE1, PRKN, PAWR, PAX2, PBX1, FGF3, PCYT1A, PDCD1, PDE4A, CREB1, MAP2K6, EIF2AK2, FGF12, RMRP, RPA1, RPL15, RPL17, RPL34, RPN2, RRAD, RRAS, S100A9, SAFB, SALL2, SAI1, TSPAN31, SAT1, CCL1, CCL2, CCL11, CCL15, CCL18, CCL20, CXCL11, CFTR, CEBPB, F3, ABCE1, RIT1, HTRA1, RELB, KLK10, PSMB9, PSMD4, PTCH1, FEN1, CKS1B, CHRNA3, CHGA, PTPN6, PVT1, RAC1, RAC3, RAD9A, RAD23B, FASN, RAF1, RAP1A, RARRES2, RBL2, RBM3, RBM4, RBP2, RELA, MUC4, MTR, DDX5, FOXA2, HOXA1, HOXA9, HOXA13, HOXD13, HP, HPGD, ERAS, HSPG2, ICAM1, ICAM2, ICAM3, ID1, IFNB1, IFNGR1, IGFBP1, FLT1, CCN1, IL3, CYP1B1, FLNB, IL7R, IL9, FOXO1, FOXA3, HLA-G, IL12A, HLA-DRB1, GAS6, GJA1, G6PD, GLI2, GNA12, DCK, DAPK1, GPR39, GRN, DAP, NR3C1, DACH1, DAB2, GRP, GSK3B, GSR, CYP24A1, FZD2, CYP2C9, HDGF, CYP2C19, HLA-DOA, HLA-DQA1, IL11, IL12RB1, MTTP, MCM7, FOXC1, CTNNA2, MFGE8, CCN2, MAP3K11, MMP1, ACE, FGFR4, MMP10, MMP13, CTBP2, MPO, MSH3, MSI1, MST1, MT1E, MT2A, MT3, CSTA, CYTB, MTHFD1, ND4, ND5, FOXC2, SMAD7, IL13, SMAD5, IL15, IL15RA, PDX1, ITGA6, IVL, JAK1, JAK2, CYLD, CXADR, KRT1, KRT7, KRT10, KRT19, STMN1, CTSL, LGALS9, LLGL2, LLGL1, LMX1B, LOX, TM4SF1, FOXM1, MAD2L1, SEL1L, SHH, SHMT2, F2RL3, GPRC5A, PIAS2, CLDN1, CCNE2, DCLK1, AURKB, NOLC1, RAB11B, IL32, NOG, MSC, UBE2L6, DCN, GRAP2, MAP4K4, MAGED1, PTGES, CHD1L, AKAP12, ISG15, MDC1, PCLAF, RASSF2, MAP3K14, LIMD1, BMS1, BCL10, LTBP4, RECK, CUL4A, CUL2, PPM1D, IFITM1, STC2, USO1, AKR1C3, BECN1, URI1, RIPK1, TNFRSF14, TNFRSF6B, TNFRSF11A, SCEL, GADD45A, BANF1, NRP1, CCN5, HDAC3, CDK5R1, PER2, EIF4A3, MAML1, CDX2, NXF1, ARL6IP5, AHSA1, TXNIP, PDPN, POSTN, CELF1, PTGES3, HSPH1, EPHA3, JTB, GADD45G, FASTK, BTG3, MLLT11, TMED10, FERMT2, KCNQ1OT1, SPINK5, IL24, CNMD, CD160, FSTL1, CAV2, CIB1, DDIT3, SPATA2, RAPGEF3, FARP2, RBX1, HDAC6, PDCD6, PARP2, DNAJB6, ABCB6, DNM1L, TSPAN1, ARL4C, TRAP1, ARFRP1, G3BP1, GDF11, TRIB1, MSLN, AKAP8, BCAS2, APC2, PAK4, TNIP1, ERBB3, RACK1, FZD7, BAP1, AXIN1, TCF4, ZEB1, TCF21, TRBV20OR9-2, TDO2, TERF1, EVPL, CDH3, TGFA, ETV1, TGFBI, TGFBR1, ETS1, CDC42, THRB, THY1, TIMP1, TIMP2, TLE2, TSPAN7, TSPAN8, TM7SF2, TMPO, TMSB4X, TCF7L2, TAP1, TAM, TAGLN, SIX1, SIX3, SLC1A5, SLC3A2, SLC11A1, SLC22A1, SMARCA2, SMARCA4, SIGLEC1, SNAI1, SNCA, SNCG, FSCN1, SOAT1, CDKN1C, SPRR3, SSR1, F2R, SSX2, STAT1, STC1, SULT1A1, SYT1, TOP1, ERCC5, CDC25A, TPM2, WRN, XIST, XPC, CD80, XRCC5, YES1, YES1P1, PCGF2, ZBTB17, ZNF208, CD3E, PRDM2, IL1R2, MANF, USP7, ST8SIA4, AIMP2, TFPI2, CCNG2, HMGA2, SLC7A5, MIA, NRIP1, WNT2B, WNT10B, VRK1, CD59, CDC20, TPT1, TRH, CD63, TRPC6, TSC1, ABCA4, ERCC4, UBE2D3, UBE2E2, UCP1, VIM, SLC35A2, UGT1A, UGT2B4, UMOD, UMPS, USP4, NR1H2, ERCC3, VHL, EZR, MAPKAPK2
    • Carcinoma Of Esophagus Orphanet
      Esophageal carcinoma (EC) is a tumor arising in the epithelial cells lining the esophagus and can be divided into two subtypes: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC). Epidemiology The estimated annual incidence of EC in Europe is approximately 1/13,300. Clinical description The disease usually presents between the ages of 50-70 years. It is often asymptomatic until it has reached an advanced disease stage with the first symptoms usually being difficulty in swallowing (dysphagia), especially present when swallowing dry foods. Unintentional weight loss is also common. Manifestations of back or chest pain, hoarseness of voice, unexplained coughing, protracted hiccups, and severe reflux may be presenting or associated symptoms.
    • Esophageal Cancer Mayo_clinic
      Overview Esophageal cancer is cancer that occurs in the esophagus — a long, hollow tube that runs from your throat to your stomach. Your esophagus helps move the food you swallow from the back of your throat to your stomach to be digested. Esophageal cancer usually begins in the cells that line the inside of the esophagus. Esophageal cancer can occur anywhere along the esophagus. More men than women get esophageal cancer. Esophageal cancer is the sixth most common cause of cancer deaths worldwide.
  • Myotonic Dystrophy Type 2 Gene_reviews
    Posterior subcapsular cataracts detectable as nonspecific vacuoles and opacities on direct ophthalmoscopy or as pathognomonic posterior subcapsular red and green iridescent opacities on slit lamp examination Cardiac conduction defects or progressive cardiomyopathy, the former diagnosable as atrioventricular or various intraventricular conduction defects on routine ECG and the latter identifiable as a dilated cardiomyopathy on echocardiography Insulin insensitivity that can appear clinically as impaired normalization of glucose on a glucose tolerance test despite normal or elevated serum insulin concentrations, and which predisposes to hyperglycemia and diabetes mellitus Hypogammaglobulinemia, defined as low gamma protein fraction on serum protein electrophoresis or low immunoglobulin G or immunoglobulin M content on immunoprotein electrophoresis, which occurs in 75% of adults with DM2 but has not been associated with any clinical abnormalities.
    CNBP, DMPK, NKX2-5, CCT3, CLCN1, INSR, MBNL1, IDE, ZNF273, TLR4, CELF1, UCP1, TNF, HP, VDR, IAPP, LPL, GCG, FXN, LEP, VEGFA, SFRP4, SLC30A10, DIO2, AGT, ACE, SCN4A, PPARG, SLC30A8, SLC22A1, XRCC3, SI, SLC2A4, STC1, SST, TAC3, TAGLN, TGFB1, TK2, TNFRSF1B, TLR3, ACTB, MTMR1, EIF2S2, MIR30C1, MIR140, MIR130B, MIR130A, PGP, BEAN1, TRPM6, SLC25A21, P2RY12, DCLRE1C, PRDM16, RETN, HSPA14, ADIPOR1, REM1, IGHD1-14, ATXN10, ATF6, PPARGC1A, SHBG, ADIPOQ, CD163, MGAM, RAPGEF5, PTPN1, SELP, HSPA9, HNF4A, HFE, GIP, GCK, GAP43, FASN, EIF2S3, EIF2S1, EEF2, DPP4, DAG1, CYBA, CHI3L1, CD59, CAV1, CASR, BPI, AR, AQP7, APOB, APOA1, HSPA4, HSPD1, SELE, IFNA1, BRD2, RAN, RAD23B, PVR, ADRB3, MAPK3, PPP2R2B, PPARA, POU2F1, PLG, SERPINE1, ODC1, NEDD4, MYD88, MT1A, LEPR, IL15, IL10, IL6, IL4, IFNA13, MIR30C2
    • Myotonic Dystrophy Type 2 Gard
      Myotonic dystrophy type 2, one of the two types of myotonic dystrophy , is an inherited muscular dystrophy that affects the muscles and other body systems (e.g., heart, eyes, and pancreas). It is characterized by prolonged muscle tensing ( myotonia ) as well as muscle weakness, pain, and stiffness. Signs and symptoms usually develop during a person's twenties or thirties. Muscles in the neck, fingers, elbows, and hips are typically affected; facial and ankle muscles are less commonly involved. The severity of myotonic dystrophy type 2 varies widely among affected people, even among family members.
    • Proximal Myotonic Myopathy Orphanet
      A rare myotonic dystrophy of juvenile or adult-onset characterized by mild and fluctuating myotonia, muscle weakness, and rarely cardiac conduction disorders. Epidemiology Prevalence estimates of around 1/100,000 in Germany and 1/600,000 in the United Kingdom have been suggested. Most cases have been reported in ethnic Europeans (mainly in Eastern Europe with a founder effect). Clinical description The clinical presentation is marked by significant variability as is the age of onset (juvenile to late adulthood). The primary manifestations include muscle weakness (with early involvement of neck flexors or finger flexors, later involving hip girdle muscles), myotonia, and possibly severe fluctuating or episodic muscle pain, and stiffness.
    • Myotonic Dystrophy 2 Omim
      A number sign (#) is used with this entry because myotonic dystrophy-2 (DM2/PROMM) is caused by heterozygous expansion of a CCTG repeat in intron 1 of the zinc finger protein-9 gene (ZNF9; 116955). Normal ZNF9 alleles have up to 30 repeats; pathogenic alleles contain from 75 to 11,000 repeats (Todd and Paulson, 2010). Description Myotonic dystrophy (DM) is a multisystem disorder and the most common form of muscular dystrophy in adults. Individuals with DM2 have muscle pain and stiffness, progressive muscle weakness, myotonia, male hypogonadism, cardiac arrhythmias, diabetes, and early cataracts. Other features may include cognitive dysfunction, hypersomnia, tremor, and hearing loss (summary by Heatwole et al., 2011).
  • Alpha-Thalassemia Gene_reviews
    The terms " α-thalassemia 1 " and " α-thalassemia 2 " (referring to α-thalassemia silent carrier and α-thalassemia trait, respectively) are no longer in use [Weatherall et al 1988]. MCS-R2, a m ultispecies c onserved s equence previously known as HS-40, is a cis -acting regulatory element about 40 kb upstream of HBZ that is required for α-globin expression [reviewed by Farashi & Harteveld 2018] (see Figure 1).
    HBA1, HBA2, HBB, ATRX, SEA, HBG2, G6PD, HBZ, PMCH, UGT1A1, ATR, SCN8A, COL9A2, COL9A3, COMP, HBG1, COL9A1, MYB, HP, HBS1L, RN7SL263P, PSMA5, EPO, DAXX, AP5Z1, OR10A4, KLF1, TP53, DOCK11, BCL11A, UGT1A10, UGT1A6, UGT1A7, UGT1A8, F3, AHSP, FASTK, UGT1A4, SLCO1B1, CD19, LUC7L, RUNX1, HAMP, TSPYL2, NSD1, TMPRSS13, ATAD1, LMLN, FTMT, SCLT1, CDAN1, EPGN, LINC01194, MIR144, ZMPSTE24, NPRL3, RGS6, RNGTT, HBD, DAP, CR1, HFE, HMOX1, CEBPD, LMNA, MSMB, MST1, MTHFR, CD37, PDR, PGD, PKD1, CD36, RAG2, RASA1, CD34, ADCY9, SMARCA2, SMARCA4, TEK, TERC, TFRC, TGFBR3, VCAM1, HBFQTL2, ACTB
    • Alpha Thalassemia Medlineplus
      Alpha thalassemia is a blood disorder that reduces the production of hemoglobin . Hemoglobin is the protein in red blood cells that carries oxygen to cells throughout the body. In people with the characteristic features of alpha thalassemia, a reduction in the amount of hemoglobin prevents enough oxygen from reaching the body's tissues. Affected individuals also have a shortage of red blood cells (anemia ), which can cause pale skin, weakness, fatigue, and more serious complications. Two types of alpha thalassemia can cause health problems. The more severe type is known as hemoglobin Bart hydrops fetalis syndrome, which is also called Hb Bart syndrome or alpha thalassemia major.
    • Hemoglobin H Disease Orphanet
      Hemoglobin H (HbH) disease is a moderate to severe form of alpha-thalassemia (see this term) characterized by pronounced microcytic hypochromic hemolytic anemia. Epidemiology HbH disease is predominantly seen in Southeast Asia, the Middle East and the Mediterranean. Exact prevalence is not known but has been reported to be about 1/1,000,000 for severe forms of alpha-thalassemia in Northern Europe and North America. Clinical description Clinical features are highly variable and generally develop in the first years of life but may not develop until adulthood in some patients. Initial signs may be noticed only during routine hematologic analyses.
    • Alpha-Thalassemia Orphanet
      An inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture depending on the number of affected alleles. Epidemiology Like other globin gene disorders, alpha-thalassemia is highly prevalent in all tropical and subtropical regions (around 1/10,000), particularly in the African equatorial belt. Intermediate and severe forms of alpha-thalassemia are very rare in North America and Northern Europe (about 1/1,000,000), and are predominantly seen in immigrant populations from South-East Asia or Mediterranean countries. Clinical description The disease can be classified into clinical subtypes of increasing severity: silent alpha thalassemia, alpha thalassemia trait (or alpha thalassemia minor), hemoglobin H disease (HbH), and Hb Bart's hydrops fetalis. A rare form called alpha-thalassemia-intellectual deficit syndrome linked to chromosome 16 (16p13.3) has also been identified (see these terms).
    • Alpha-Thalassemia Omim
      A number sign (#) is used with this entry because of evidence that alpha-thalassemia is caused by mutations in the alpha-globin genes (HBA1, 141800; HBA2, 141850). Sequences 30 to 50 kb upstream from the alpha-globin gene cluster, referred to as the locus control region alpha (LCRA; 152422), have been found to be deleted in cases of alpha-thalassemia with structurally intact alpha-globin genes. The molecular and clinical aspects of the severe alpha-thalassemia syndromes were reviewed by Higgs (1993) and Chui and Waye (1998). Weatherall (2001) reviewed phenotype-genotype relationships in monogenic diseases based on studies of the thalassemias. The remarkable phenotypic diversity of the beta-thalassemias reflects the heterogeneity of mutations at the HBB locus, the action of many secondary and tertiary modifiers, and a wide range of environmental factors.
    • Alpha-Thalassemia Gard
      Alpha-thalassemia is a blood disorder that reduces the body's production of hemoglobin . Affected people have anemia, which can cause pale skin, weakness, fatigue, and more serious complications. Two types of alpha-thalassemia can cause health problems: the more severe type is known as Hb Bart syndrome; the milder form is called HbH disease. Hb Bart syndrome may be characterized by hydrops fetalis ; severe anemia; hepatosplenomegaly; heart defects; and abnormalities of the urinary system or genitalia. Most babies with this condition are stillborn or die soon after birth.
  • Epithelioid Sarcoma Wikipedia
    S2CID 30710443 . ^ Henderson, T. O.; Whitton, J.; Stovall, M.; Mertens, A. C.; Mitby, P.; Friedman, D.; Strong, L. ... M.; Guise, C. P.; Maroz, A.; Anderson, R. F.; Patterson, A. V.; Stachelek, G. C.; Glazer, P. M.; Matteucci, M. D.; Hart, C. P. (2012). ... PMID 25185097 . ^ a b c d Wilky, Breelyn; Goldberg, John M. (April 14, 2014). "Immunotherapy in sarcoma: A new frontier" . ... PMID 12528773 . ^ a b c Arora, Amit; Scholar, Eric M. (2005). "Role of Tyrosine Kinase Inhibitors in Cancer Therapy".
    TP53, PIK3CA, GSTP1, MAML3, PRAME, TNF, SOX2, SMARCA4, PAX3, NF1, MCL1, IFNG, ZNF667-AS1, CSF2, SMARCB1, CD34, CCND1, EZH2, SMARCA1, ERG, EGFR, EWSR1, FOSB, MIR206, CD109, ASS1, VIM, HMGA2, ARID1A, MIR765, MIR671, HDAC9, CIC, PLA2G15, MIR186, FXYD5, FASLG, ACSS2, TWIST1, MIB1, DHDDS, MIR193A, ACCS, CHPT1, BTK, BCL2, MKI67, FLI1, FLII, FN1, GPC3, GLI1, HGF, IL2, CD99, MMP2, TGFBR2, NT5E, CCK, ABCB1, FAS, PTEN, REN, CAPZB, TGFB1, ALDH1A1
    • Epithelioid Sarcoma Gard
      Epithelioid sarcoma (ES) is a rare cancerous tumor that most often occurs in the soft tissue of the fingers, hands and forearms of young adults. It can also occur elsewhere in the body. ES usually begins as a painless, firm growth or bump that may be accompanied by an open wound ( ulceration ) in the skin covering the growth. This type of tumor often comes back after treatment or spreads to other parts the body (metastasis). The cause of epithelioid sarcoma is unknown. It is diagnosed by a clinical examination and by testing a small sample of the tumor (biopsy) in a laboratory. Epithelioid sarcoma is treated with surgery to remove all the cancer cells ( wide local excision ) and sometimes with radiation therapy.
    • Epithelioid Sarcoma Orphanet
      Epithelioid sarcoma is a rare, soft tissue tumor characterized by high incidence of local recurrence, regional lymph node involvement and distant metastases. It commonly affects the soft tissue under the skin of a finger, hand, forearm, lower leg or foot, less often other areas of the body.
  • Alström Syndrome Gene_reviews
    Early childhood-onset obesity, primarily truncal with a body mass index (BMI: kg/m 2 ) greater than 25 (for adults) or greater than the 95th centile on age- and gender-appropriate charts Progressive bilateral sensorineural hearing impairment (initially in the high-frequency range), usually diagnosed between ages one and ten years, although onset can vary Acute infantile-onset cardiomyopathy and/or adolescent- or adult-onset restrictive cardiomyopathy Insulin resistance / type 2 diabetes mellitus (T2DM), the result of tissue resistance to the actions of insulin, usually present in childhood and manifest as elevated plasma insulin concentration and glucose intolerance.
    ALMS1, DCTN1, GH1, GHRH, PLXNA2, RHO, MKKS, DYSF, SLC4A5, CDH23, CEP290, LBX2
    • Alstrom Syndrome Omim
      A number sign (#) is used with this entry because of evidence that Alstrom syndrome (ALMS) is caused by homozygous or compound heterozygous mutation in the ALMS1 gene (606844) on chromosome 2p13. Description Alstrom syndrome is an autosomal recessive disorder characterized by progressive cone-rod dystrophy leading to blindness, sensorineural hearing loss, childhood obesity associated with hyperinsulinemia, and type 2 diabetes mellitus. Dilated cardiomyopathy occurs in approximately 70% of patients during infancy or adolescence. Renal failure, pulmonary, hepatic, and urologic dysfunction are often observed, and systemic fibrosis develops with age (summary by Collin et al., 2002; Marshall et al., 2007). Clinical Features Although this disorder bears many similarities (retinitis pigmentosa, deafness, obesity, and diabetes mellitus) to the Bardet-Biedl syndrome (209900), there is no mental defect, polydactyly, or hypogonadism (Alstrom et al., 1959).
    • Alström Syndrome Wikipedia
      Rare genetic disorder involving childhood obesity and multiple organ dysfunction Alström syndrome Other names Alström–Hallgren syndrome Transaxial image of the chest at the level of the heart illustrating the typical degree of subcutaneous and epicardial adipose tissue (shown in white) in a patient with Alström syndrome; hence the difficulty in imaging by echocardiography Specialty Medical genetics , ophthalmology , neurology Alström syndrome ( AS ), also called Alström–Hallgren syndrome , [1] is a very rare autosomal recessive genetic disorder characterised by childhood obesity and multiple organ dysfunction. Symptoms include early-onset type 2 diabetes , cone-rod dystrophy resulting in blindness, sensorineural hearing loss and dilated cardiomyopathy . Endocrine disorders typically also occur, such as hypergonadotrophic hypogonadism and hypothyroidism , as well as acanthosis nigricans resulting from hyperinsulinemia . Developmental delay is seen in almost half of people with Alström syndrome. [2] It is caused by mutations in the gene ALMS1 , which is involved in the formation of cellular cilia , making Alström syndrome a ciliopathy . At least 239 disease-causing mutations in ALMS1 have been described as of 2015 [update] . [3] Alström syndrome is sometimes confused with Bardet–Biedl syndrome , another ciliopathy which has similar symptoms, but Bardet–Biedl syndrome tends to have later onset in its symptoms, includes polydactyly and is caused by mutations in BBS genes. [4] There is no cure for Alström syndrome.
    • Alström Syndrome Medlineplus
      Alström syndrome is a rare condition that affects many body systems. Many of the signs and symptoms of this condition begin in infancy or early childhood, although some appear later in life. Alström syndrome is characterized by a progressive loss of vision and hearing, a form of heart disease that enlarges and weakens the heart muscle (dilated cardiomyopathy ), obesity, type 2 diabetes (the most common form of diabetes), and short stature. This disorder can also cause serious or life-threatening medical problems involving the liver , kidneys, bladder , and lungs . Some individuals with Alström syndrome have a skin condition called acanthosis nigricans, which causes the skin in body folds and creases to become thick, dark, and velvety. The signs and symptoms of Alström syndrome vary in severity, and not all affected individuals have all of the characteristic features of the disorder.
    • Alström Syndrome Gard
      Alström syndrome is a rare genetic disorder that affects many body systems. Symptoms develop gradually, beginning in infancy, and can be variable. In childhood, the disorder is generally characterized by vision and hearing abnormalities, childhood obesity, and heart disease (cardiomyopathy). Over time, diabetes mellitus, liver problems, and slowly progressive kidney dysfunction which can lead to kidney failure may develop. Alström syndrome is caused by mutations in the ALMS1 gene. It is inherited in an autosomal recessive manner.
    • Alström Syndrome Orphanet
      A rare multisystemic disorder characterized by cone-rod dystrophy, hearing loss, obesity, insulin resistance and hyperinsulinemia, type 2 diabetes mellitus, dilated cardiomyopathy (DCM), and progressive hepatic and renal dysfunction. Epidemiology Alström syndrome (AS) has a suggested prevalence of 1/1000,000 in Europe and North America. A much higher frequency was reported in some populations with a high level of consanguinity or those that are geographically isolated. More than 950 cases have been identified worldwide. Clinical description The clinical features, age of onset, and severity can vary greatly among and within families. Cone-rod retinal dystrophy usually develops within a few weeks after birth, with the first symptoms being nystagmus and extreme photodysphoria or light sensitivity.
  • 2016 Munich Shooting Wikipedia
    Retrieved 27 April 2017 . ^ a b c d e f g h i j k l m n o Investigations to the Munich killing spree completed .
  • Abortion In New York Wikipedia
    Retrieved 2019-05-26 . ^ a b Alford, Suzanne M. (2003). "Is Self-Abortion a Fundamental Right?"
  • Hiv/aids In Taiwan Wikipedia
    J Infect Dis (in press). ^ Su L, Graf M, Zhang Y, et al. Characterization of a virtually full-length human immunodeficiency virus type 1 genome of a prevalent intersubtype (C/B') recombinant strain in China.
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