Hepatic porphyria Specialty Endocrinology Hepatic porphyrias is a form of porphyria in which toxic porphyrin molecules build up in the liver . Hepatic porphyrias can result from a number of different enzyme defiencies. [1] Examples include (in order of synthesis pathway): Acute intermittent porphyria Porphyria cutanea tarda and Hepatoerythropoietic porphyria Hereditary coproporphyria Variegate porphyria See also [ edit ] Erythropoietic porphyria References [ edit ] ^ "OMIM - PORPHYRIA, CONGENITAL ERYTHROPOIETIC" . Retrieved 2008-12-04 . External links [ edit ] Classification D ICD - 10 : E80 ICD - 9-CM : 277.1 MeSH : D017094 Porphyrias,+Hepatic at the US National Library of Medicine Medical Subject Headings (MeSH) www.drugs-porphyria.com www.porphyria-europe.com v t e Heme metabolism disorders Porphyria , hepatic and erythropoietic ( porphyrin ) early mitochondrial: ALAD porphyria Acute intermittent porphyria cytoplasmic: Gunther disease/congenital erythropoietic porphyria Porphyria cutanea tarda / Hepatoerythropoietic porphyria late mitochondrial: Hereditary coproporphyria Harderoporphyria Variegate porphyria Erythropoietic protoporphyria Hereditary hyperbilirubinemia ( bilirubin ) unconjugated: Gilbert's syndrome Crigler–Najjar syndrome Lucey–Driscoll syndrome conjugated: Dubin–Johnson syndrome nd sheet Rotor syndrome This article about an endocrine, nutritional, or metabolic disease is a stub . You can help Wikipedia by expanding it . v t e
Caustic ingestions in adults usually involve larger amounts of ingested material during attempts of self harm. [1] Due to the greater amount of material usually ingested; injuries are often more severe in the intentional ingestions of adolescents and adults as compared to those of children. [1] Commonly ingested substances include ammonium hydroxide (found in general cleaner and grease remover), sodium hydroxide or potassium hydroxide (found in drain opener or oven cleaner), sodium hypochlorite (bleach), oxalic acid (metal polish) and hydrochloric acid (toilet bowl cleaner). [1] Storage of caustic substances in water or drink containers is a risk factor for accidental ingestion of these materials, particularly in children. [2] Boys of preschool age are at the greatest risk of accidental caustic ingestion. [3] Prevention [ edit ] Preventative measures have been recommended that are intended to decrease the risk of accidental ingestion of caustic substances including": [3] Keeping caustic substances in locked cabinets or on upper shelves Not storing chemical substances in food or drink containers Not keeping large amounts of detergent in the home Not mentioning a drug as "candy" when giving it as medication Keeping the phone number for poison control in the home Keeping caustic substances in labelled containers References [ edit ] ^ a b c d e f g h i j k l m n o p q r s Longo, Dan L.; Hoffman, Robert S.; Burns, Michele M.; Gosselin, Sophie (30 April 2020).
The Sistrunk procedure has a reoccurrence rate of less than 5%, proving it is extremely effective at removing the majority of traces of the persistent thyroglossal duct. [6] References [ edit ] ^ Kurt A, Ortug C, Aydar Y, Ortug G (April 2007). "An incidence study on thyroglossal duct cysts in adults".
A veterinarian must be contacted if there is a risk of misdiagnosis with other, more serious conditions. [1] See also [ edit ] Ecthyma List of cutaneous conditions List of immunofluorescence findings for autoimmune bullous conditions References [ edit ] ^ a b c d e f g Winter, Agnes; Charmley, Judith (1999).
. ^ a b Siedlecki, Jakob; Schworm, Benedikt; Priglinger, Siegfried G. (December 2019). "The Pachychoroid Disease Spectrum—and the Need for a Uniform Classification System".
This condition has several different names: 22q11.2 deletion syndrome, Velocardiofacial syndrome, DiGeorge syndrome, conotruncal anomaly face syndrome, Opitz G/BBB syndrome, and Cayler cardiofacial syndrome.
Trisomy 22 is a chromosome disorder in which an extra (third) copy of chromosome 22 is present in every cell of the body where there should normally only be two copies. This condition is commonly found in miscarriages, but only rarely in liveborn infants. Most affected individuals die shortly before or shortly after birth due to severe complications. Common features include an underdeveloped midface (midface hypoplasia) with flat/broad nasal bridge, malformed ears with pits or tags, cleft palate, hypertelorism (wide-spaced eyes), microcephaly and other cranial abnormalities, congenital heart disease , genital abnormalities, and intrauterine growth restriction (IUGR).
Sunburn, childbirth, weightlifting [3] Gua Sha , a Chinese treatment that scrapes the skin High-G training Hickey Asphyxiation Choking game Oral sex [4] Non-infectious conditions [ edit ] Vitamin C deficiency, scurvy [3] Vitamin K deficiency [3] Leukemia [3] Thrombocytopenia – Low platelet counts or diminished platelet function (e.g., as a side effect of medications or during certain infections) can give rise to petechial spots [1] clotting factor deficiencies – ( Von Willebrand disease ) Hypocalcemia Idiopathic thrombocytopenic purpura Coeliac disease Aplastic anaemia Lupus Kwashiorkor or Marasmus – Childhood protein-energy malnutrition Erythroblastosis fetalis Henoch–Schönlein purpura Kawasaki disease Schamberg disease Ehlers–Danlos syndrome Sjögren syndrome – Petechial spots could occur due to vasculitis , an inflammation of the blood vessels.
Identification criteria [ edit ] According to the World Health Organization, if a woman presents any of the conditions below during pregnancy, childbirth or within 42 days of termination of pregnancy and survives, she is considered as a maternal near miss case. [10] Cardiovascular dysfunction a) Shock b) Cardiac Arrest c) Severe hypoperfusion (lactate >5 mmol/L or >45 mg/dL) d) Severe acidosis (pH<7.1) e) Use of continuous vasoactive drugs f) Cardio-pulmonary resuscitation Respiratory dysfunction g) Acute cyanosis h) Gasping i) Severe tachypnea (respiratory rate>40 breaths per minute) j) Severe bradypnea (respiratory rate<6 breaths per minute) k) Severe hypoxemia (O2 saturation <90% for ≥60min or PAO2/FiO2<200) l) Intubation and ventilation not related to anaesthesia Renal dysfunction m) Oliguria non responsive to fluids or diuretics n) Severe acute azotemia (creatinine >300 μmol/ml or >3.5 mg/dL) o) Dialysis for acute renal failure Coagulation dysfunction p) Failure to form clots q) Severe acute thrombocytopenia (<50,000 platelets/ml) r) Massive transfusion of blood or red cells (≥ 5 units) Hepatic dysfunction s) Jaundice in the presence of pre-eclampsia t) Severe acute hyperbilirubinemia (bilirubin>100 μmol/L or >6.0 mg/dL) Neurologic dysfunction u) Prolonged unconsciousness or coma (lasting >12 hours) v) Stroke w) Uncontrollable fit / status epilepticus x) Global paralysis Uterine dysfunction y) Hysterectomy due to uterine infection or haemorrhage Sources [ edit ] Adisasmita, Asri; et al. (2008).