Linear Iga Bullous Dermatosis

Linear IgA bullous dermatosis is a rare immune-mediated blistering skin disease frequently associated with medication exposure, especially vancomycin, with men and women being equally affected.^:135 It was first described by Tadeusz Chorzelski in 1979 and may be divided into two types:^:587

• Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. This disease can often be difficult to treat even with usually effective medications such as rituximab.
• Childhood linear IgA disease (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13.

• 

  Micrograph: Subepidermal blister formation and neutrophils

• 

See also

• Skin lesion
• List of cutaneous conditions
• List of target antigens in pemphigoid
• List of immunofluorescence findings for autoimmune bullous conditions