Primary Systemic Amyloidosis
Watchlist
Retrieved
2021-01-23
Source
Trials
—
Genes
CCND1,
LINC02343,
CBX7,
LINC00457,
SMARCD3,
TTR,
DNAH11,
CD38,
SCT,
GDF15,
NPPB,
SPP1,
IGKV2-29,
MIR34A,
SMN1,
SMN2,
ST2,
TNF,
BMS1P20,
KRT20,
IGKV1-8,
BABAM2,
GLIPR1,
WDHD1,
MAGEC2,
SLC1A4,
PLXNB2,
IGKV3D-15,
IGKV1D-8,
IGKV3-20
CCND1,
LINC02343,
CBX7,
LINC00457,
SMARCD3,
TTR,
DNAH11,
CD38,
SCT,
GDF15,
NPPB,
SPP1,
IGKV2-29,
MIR34A,
SMN1,
SMN2,
ST2,
TNF,
BMS1P20,
KRT20,
IGKV1-8,
BABAM2,
GLIPR1,
WDHD1,
MAGEC2,
SLC1A4,
PLXNB2,
IGKV3D-15,
IGKV1D-8,
IGKV3-20,
PRAME,
ALB,
SDC1,
FGA,
BCR,
PRDM1,
CAT,
MS4A1,
CDA,
CDH1,
CRP,
CSF3,
CYP1B1,
DDT,
ETFA,
GSN,
FAS,
IGKV@,
LGALS3,
LGALS4,
MDK,
MMP1,
MMP2,
MUC1,
MYD88,
NCAM1,
PFDN5,
RPS27A,
SAA1
Drugs
Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpesvirus-6, Epstein Barr virus and adenovirus,
Carboxy pyrrolidine hexanoyl pyrrolidine carboxylate,
Chimeric fibril-reactive IgG1k monoclonal antibody 11-1F4
Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpesvirus-6, Epstein Barr virus and adenovirus,
Carboxy pyrrolidine hexanoyl pyrrolidine carboxylate,
Chimeric fibril-reactive IgG1k monoclonal antibody 11-1F4,
Daratumumab
(
DARZALEX
),
Eprodisate,
Humanised IgG1 kappa antibody against serum amyloid A and AL amyloid,
Iodine (123I) Serum Amyloid P,
Ixazomib
(
NINLARO
),
N-(3,4-dihydroxyphenyl)-3,4-dihydroxybenzamide,
Recombinant monoclonal antibody to human serum amyloid P component,
florbetaben (18F),
haematopoietic stem cells and blood progenitors umbilical cord-derived expanded with (1R, 4R)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine dihydrobromide dihydrate
Registered!
Primary systemic amyloidosis (PSA) is a form of AL amyloidosis (see this term) caused by the aggregation and deposition of insoluble amyloid fibrils derived from misfolded monoclonal immunoglobulin light chains usually produced by a plasma cell tumor (see this term) and characterized by multiple organ involvement.