Glycoproteinosis

Glycoproteinosis are lysosomal storage diseases affecting glycoproteins, resulting from defects in lysosomal function. The term is sometimes reserved for conditions involving degradation of glycoproteins.

Types

• (E77.0) Defects in post-translational modification of lysosomal enzymes
  • Mucolipidosis II (I-cell disease)
  • Mucolipidosis III (pseudo-Hurler polydystrophy)
• (E77.1) Defects in glycoprotein degradation
  • Aspartylglucosaminuria
  • Fucosidosis
  • Mannosidosis
  • Sialidosis (mucolipidosis I)

Another type, recently characterized, is galactosialidosis.