Desmoplastic/nodular Medulloblastoma

Watchlist

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Retrieved

2021-01-23

Source

Orphanet

Trials

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Genes

SUFU, PTCH1, KDM4C, APC, IRS2, ATOH1, SCG5, SKP2, STAT3, VAV1, KAT6A, BRD3, PTCH2, SCML2, S100A4, RASSF1, KDM4B, BRD4, PRAME, EHMT1, L3MBTL2, L3MBTL3, STRADA, S100A6, S100A10, MPL, MYC, BRCA2, CCNE1, CDK6, CTNNB1, DNMT1, ERBB2, ESR2, FLI1, HIC1, BRD2, SMYD4, MYCL, MYCN, OTX2, PDGFRA, PIK3CG, MSH2, EFS, MSH6, GLI1, SOX11, SOX4, SMO, BCAS3, PAX5, SHH, RPS6KB1

Drugs

16-base single-stranded peptide nucleic acid oligonucleotide linked to a 7-amino acid peptide, Boswellia serrata resin dry extract, Humanised IgG1 monoclonal antibody against the receptor-binding site of human placental growth factor

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Desmoplastic/nodular medulloblastoma is a histological variant of medulloblastoma (see this term), an embryonic malignancy, often located in one of the cerebellar hemispheres, occurring most frequently in adults and manifesting with symptoms such as vomiting and headache.