Retinoschisis Of Fovea

Clinical Features

Lewis et al. (1977) reported 3 sisters (including a set of identical twins), of nonconsanguineous parents, with mild visual loss and bilateral foveal dystrophy closely resembling that of juvenile X-linked retinoschisis (312700). Electrophysiologic changes were less severe than in the X-linked disorder. Foveal retinoschisis occurs in almost all cases of X-linked retinoschisis.

Noble et al. (1978) described foveal retinoschisis in a brother and sister whose parents were distant cousins and who showed signs of associated rod-cone dystrophy: nyctalopia, hyperopia, paramacular tapetal sheen reflex, and abnormal electroretinogram.